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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Immunohistochemistry [1]
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- Product number
- R1041X - Provider product page
- Provider
- Acris Antibodies GmbH
- Proper citation
- Acris Antibodies GmbH Cat#R1041X, RRID:AB_978642
- Product name
- anti Collagen type IV
- Antibody type
- Polyclonal
- Antigen
- Collagen type IV purified from Human and Bovine placenta.
- Reactivity
- Human, Bovine
- Host
- Rabbit
- Vial size
- 0.5 mg
- Concentration
- 1.0 mg/ml (by UV absorbance at 280 nm)
Submitted references AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.
The epidermal basement membrane is a composite of separate laminin- or collagen IV-containing networks connected by aggregated perlecan, but not by nidogens.
Perlecan is critical for heart stability.
Rodriguez-Teja M, Gronau JH, Breit C, Zhang YZ, Minamidate A, Caley MP, McCarthy A, Cox TR, Erler JT, Gaughan L, Darby S, Robson C, Mauri F, Waxman J, Sturge J
The Journal of pathology 2015 Mar;235(4):581-92
The Journal of pathology 2015 Mar;235(4):581-92
The epidermal basement membrane is a composite of separate laminin- or collagen IV-containing networks connected by aggregated perlecan, but not by nidogens.
Behrens DT, Villone D, Koch M, Brunner G, Sorokin L, Robenek H, Bruckner-Tuderman L, Bruckner P, Hansen U
The Journal of biological chemistry 2012 May 25;287(22):18700-9
The Journal of biological chemistry 2012 May 25;287(22):18700-9
Perlecan is critical for heart stability.
Sasse P, Malan D, Fleischmann M, Roell W, Gustafsson E, Bostani T, Fan Y, Kolbe T, Breitbach M, Addicks K, Welz A, Brem G, Hescheler J, Aszodi A, Costell M, Bloch W, Fleischmann BK
Cardiovascular research 2008 Dec 1;80(3):435-44
Cardiovascular research 2008 Dec 1;80(3):435-44
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Supportive validation
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- R1041 Collagen IV antibody (Lot 25440, 1/400, 45 min RT) showed strong staining in FFPE sections of Human kidney (Left) with strong Red staining observed in glomeruli and liver (Right) with strong staining in sinusoids. Staining for both tissues was consistent with a basement membrane distribution. Slides were steamed in 0.01 M sodium citrate buffer, pH 6.0 at 99-100°C - 20 minutes for antigen retrieval. Images provided courtesy of LifeSpan Biosciences, Seattle, WA
