COL4A1

gene product
This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
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695 antibodies from 34 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
31 antibodies
GeneTex
7 antibodies
antibodies-online
249 antibodies
Invitrogen Antibodies
16 antibodies
Biorbyt
58 antibodies
Abnova Corporation
3 antibodies
Affinity Biosciences
1 antibody
Acris Antibodies GmbH
31 antibodies
NovoPro Bioscience Inc.
2 antibodies
Aviva Systems Biology
10 antibodies
LifeSpan BioSciences, Inc.
47 antibodies
OriGene
30 antibodies
NSJ Bioreagents
5 antibodies
Arigo
2 antibodies
Abgent
1 antibody
Rockland Immunochemicals, Inc.
6 antibodies
Boster Biological Technology
5 antibodies
Bioworld Technology, Inc
1 antibody
St John's Laboratory
10 antibodies
ProSci
2 antibodies
GenWay
16 antibodies
Creative Biolabs
39 antibodies
Abbkine Scientific Co.Ltd.
9 antibodies
Proteintech Group
1 antibody
Creative Diagnostics
17 antibodies
RabMAbs
1 antibody
MyBioSource
10 antibodies
R&D Systems
2 antibodies
EMD Millipore
6 antibodies
United States Biological
28 antibodies
Abbexa
6 antibodies
YO Proteins AB
3 antibodies
eBioscience, An Affymetrix Company
4 antibodies