Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- GTX108354 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX108354, RRID:AB_2036137
- Product name
- P Glycoprotein antibody
- Antibody type
- Polyclonal
- Reactivity
- Human
- Host
- Rabbit
Submitted references Increase in resistance to anticancer drugs involves occludin in spheroid culture model of lung adenocarcinoma A549 cells.
MEK inhibitor enhances sensitivity to chemotherapeutic drugs in multidrug resistant hepatocellular carcinoma cells.
A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrier.
Eguchi H, Akizuki R, Maruhashi R, Tsukimoto M, Furuta T, Matsunaga T, Endo S, Ikari A
Scientific reports 2018 Oct 11;8(1):15157
Scientific reports 2018 Oct 11;8(1):15157
MEK inhibitor enhances sensitivity to chemotherapeutic drugs in multidrug resistant hepatocellular carcinoma cells.
Meng Q, He X, Xie G, Tian Q, Shu X, Li J, Xiao Y
Oncology letters 2017 Sep;14(3):3089-3095
Oncology letters 2017 Sep;14(3):3089-3095
A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrier.
Kim DG, Bynoe MS
The Journal of clinical investigation 2016 May 2;126(5):1717-33
The Journal of clinical investigation 2016 May 2;126(5):1717-33
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (20 ?g of whole cell lysate) A: Hep3B 8% SDS PAGE GTX108354 diluted at 1:2500 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Boiled and unboiled HepG2 whole cell and membrane extracts (30 ?g) were separated by 5% SDS-PAGE, and the membrane was blotted with P Glycoprotein antibody (GTX108354) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. (WCE: whole cell extract; ME: membrane extract)