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antibody from Boster Biological Technology
Targeting: ABCB1
ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- RP1034 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-P Glycoprotein/ABCB1 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for 1853 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. 1853 information: Molecular Weight: 141479 MW; Subcellular Localization: Cell membrane ; Multi-pass membrane protein ; Tissue Specificity: Expressed in liver, kidney, small intestine and brain.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Combined effects of low-dose gambogic acid and NaI(131) in drug-resistant non-small cell lung cancer cells.
Downregulation of cytokeratin 18 enhances BCRP-mediated multidrug resistance through induction of epithelial-mesenchymal transition and predicts poor prognosis in breast cancer.
Overexpression of ILK promotes temozolomide resistance in glioma cells.
Gambogic acid as a non-competitive inhibitor of ATP-binding cassette transporter B1 reverses the multidrug resistance of human epithelial cancers by promoting ATP-binding cassette transporter B1 protein degradation.
Indole-3-carbinol alters placental cytochrome P450 1A1 and P-glycoprotein levels in rats: a potential role in intensifying fetal intrauterine growth-retardation produced by tobacco smoke.
Huang J, Zhu XL, Wu Y, Han SH, Xie Y, Yang SF, Ding M, Chen PS
Oncology letters 2021 Aug;22(2):588
Oncology letters 2021 Aug;22(2):588
Downregulation of cytokeratin 18 enhances BCRP-mediated multidrug resistance through induction of epithelial-mesenchymal transition and predicts poor prognosis in breast cancer.
Shi R, Wang C, Fu N, Liu L, Zhu D, Wei Z, Zhang H, Xing J, Wang Y
Oncology reports 2019 May;41(5):3015-3026
Oncology reports 2019 May;41(5):3015-3026
Overexpression of ILK promotes temozolomide resistance in glioma cells.
Liang F, Wang B, Bao L, Zhao YS, Zhang SM, Zhang SQ
Molecular medicine reports 2017 Mar;15(3):1297-1304
Molecular medicine reports 2017 Mar;15(3):1297-1304
Gambogic acid as a non-competitive inhibitor of ATP-binding cassette transporter B1 reverses the multidrug resistance of human epithelial cancers by promoting ATP-binding cassette transporter B1 protein degradation.
Wang X, Deng R, Lu Y, Xu Q, Yan M, Ye D, Chen W
Basic & clinical pharmacology & toxicology 2013 Jan;112(1):25-33
Basic & clinical pharmacology & toxicology 2013 Jan;112(1):25-33
Indole-3-carbinol alters placental cytochrome P450 1A1 and P-glycoprotein levels in rats: a potential role in intensifying fetal intrauterine growth-retardation produced by tobacco smoke.
Yan YE, Wang H, Wang T, Zeng HG
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 2006 Aug;58(1):39-47
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 2006 Aug;58(1):39-47
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-P Glycoprotein Picoband antibody, RP1034-1.JPGIHC(F): Mouse Intestine Tissue
- Additional image
