Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations [0]
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- Product number
- 250820 - Provider product page
- Provider
- Abbiotec
- Proper citation
- Abbiotec Cat#250820, RRID:AB_2174410
- Product name
- P-glycoprotein Antibody
- Antibody type
- Polyclonal
- Antigen
- KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human P-glycoprotein.
- Description
- P-glycoprotein 1 (multidrug resistance protein 1, MDR1) is an energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. MDR1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Genetic variation in MDR1 are the cause for patients who do not respond to drug treatment.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Storage
- Store at -20C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Submitted references P-glycoprotein trafficking at the blood-brain barrier altered by peripheral inflammatory hyperalgesia.
McCaffrey G, Staatz WD, Sanchez-Covarrubias L, Finch JD, Demarco K, Laracuente ML, Ronaldson PT, Davis TP
Journal of neurochemistry 2012 Sep;122(5):962-75
Journal of neurochemistry 2012 Sep;122(5):962-75
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