ABIN187226

antibody from antibodies-online

Targeting: ABCB1 ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1

Functional assay (Recommended by provider)

Antibody Data

Product number

ABIN187226

Provider

antibodies-online

Product name

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) antibody

Antibody type

Monoclonal

Antigen

Adriamycin-resistant human myelogenous leukemia K-562/ADM cellsMouse myeloma (P3/X63-Ag8) x immunized mouse (Balb/c) spleen cells Page 1 of 2

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

MRK16

Vial size

0.15 mg

Storage

Store at -20 °C. Aliquot to avoid freeze/thaws. Maintain sterility. Product does not contain a preservative.

References

Submitted references

Detection of multidrug-resistant protein, P-glycoprotein in childhood leukaemia and lymphoma.

Mizuno Y, Hara T, Nagata M, Tawa A, Tsuruo T, Ueda K
European journal of pediatrics 1991 Apr;150(6):416-8

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Immunohistochemical detection of multidrug resistance associated P-glycoprotein in tumour and stromal cells of human cancers.

Schlaifer D, Laurent G, Chittal S, Tsuruo T, Soues S, Muller C, Charcosset JY, Alard C, Brousset P, Mazerrolles C
British journal of cancer 1990 Aug;62(2):177-82

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Further characterization of the human adrenal-derived P-glycoprotein recognized by monoclonal antibody MRK 16 reacting with only human P-glycoprotein.

Sugawara I, Hamada H, Nakahama M, Okamoto S, Tsuruo T, Mori S
Japanese journal of cancer research : Gann 1989 Dec;80(12):1199-205

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A monoclonal antibody-Pseudomonas toxin conjugate that specifically kills multidrug-resistant cells.

FitzGerald DJ, Willingham MC, Cardarelli CO, Hamada H, Tsuruo T, Gottesman MM, Pastan I
Proceedings of the National Academy of Sciences of the United States of America 1987 Jun;84(12):4288-92