Tissue expression
Cell line expression

SMG7

gene product
C1orf16, EST1C, KIAA0250, SGA56M, SMG-7 
This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011]
More gene data

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110 antibodies from 23 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Biorbyt
10 antibodies
LifeSpan BioSciences, Inc.
15 antibodies
antibodies-online
32 antibodies
Cusabio Biotech Co., Ltd
6 antibodies
Novus Biologicals
3 antibodies
Abnova Corporation
2 antibodies
GeneTex
3 antibodies
St John's Laboratory
2 antibodies
Affinity Biosciences
1 antibody
Aviva Systems Biology
1 antibody
Invitrogen Antibodies
8 antibodies
Atlas Antibodies
1 antibody
OriGene
1 antibody
Boster Biological Technology
2 antibodies
Bioworld Technology, Inc
1 antibody
Abbkine Scientific Co.Ltd.
1 antibody
Bethyl Laboratories
1 antibody
Abbexa
2 antibodies
Abgent
1 antibody
United States Biological
12 antibodies
MyBioSource
2 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Creative Diagnostics
1 antibody