Tissue expression
Cell line expression
Protein structure
ASPM
Assembly factor for spindle microtubulesASP, Calmbp1, FLJ10517, FLJ10549, MCPH5
This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Top validated antibodies |
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Proteintech Group | ![]() |
14 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
7 references | Polyclonal |
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antibodies-online | ![]() |
4 references | Polyclonal |
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Cusabio Biotech Co., Ltd | ![]() |
Polyclonal |
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