Tissue expression
Cell line expression
Protein structure
RAMP1
Receptor activity modifying protein 1The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Top validated antibodies |
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Proteintech Group | 10327-1-AP | 3 references | Polyclonal |
WB
EL
IHC
FC |
|
Novus Biologicals | NBP1-20966 | 4 references | Polyclonal |
WB
EL |
|
Invitrogen Antibodies | 10327-1-AP | Polyclonal |
WB
IHC
FC
|
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NovoPro Bioscience Inc. | 114533 | Polyclonal |
WB
EL
IHC
FC |
||
Biorbyt | orb10480 | Polyclonal |
WB
EL
ICC
IHC |
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Enhanced validation
Supportive data in Antibodypedia
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Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider