ABIN117993

antibody from antibodies-online

Targeting: HTT HD, IT15

Western blot (Data presented on provider website)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN117993

Provider

antibodies-online

Product name

anti-Huntingtin (HTT) (pSer421) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide corresponding aa 416-424 of Human huntingtin protein. AA Sequence: Human Huntingtin protein, 3144 aa, predicted MW347. 7 kDa

Reactivity

Human

Host

Rabbit

Vial size

0.1 mg

Concentration

0.8 mg/ml

Storage

Store vial at -20°C prior to opening. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Shelf life: one year from despatch.

References

Submitted references

Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease.

Lee WC, Yoshihara M, Littleton JT
Proceedings of the National Academy of Sciences of the United States of America 2004 Mar 2;101(9):3224-9

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Calmodulin regulates transglutaminase 2 cross-linking of huntingtin.

Zainelli GM, Ross CA, Troncoso JC, Fitzgerald JK, Muma NA
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 Feb 25;24(8):1954-61