PIK3C2B

gene product
C2-PI3K, PI3K-C2beta
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq, Jul 2008]
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antibodies-online
42 antibodies
Novus Biologicals
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Abnova Corporation
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OriGene
14 antibodies
NovoPro Bioscience Inc.
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LifeSpan BioSciences, Inc.
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Invitrogen Antibodies
7 antibodies
Abgent
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Affinity Biosciences
1 antibody
Acris Antibodies GmbH
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R&D Systems
1 antibody
Proteintech Group
1 antibody
Abbkine Scientific Co.Ltd.
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MyBioSource
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Arigo
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Aviva Systems Biology
1 antibody
Creative Biolabs
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Creative Diagnostics
3 antibodies
St John's Laboratory
2 antibodies
United States Biological
39 antibodies
Sigma-Aldrich
2 antibodies
EMD Millipore
1 antibody
ProSci
1 antibody