CDC42BPA

The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008]

Description

CDC42 binding protein kinase alpha

Protein family

Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

1:q42.13 (226989865 - 227318474)

Ensembl ID

ENSG00000143776  (ver. 98.38)

Orthologs

Mouse Cdc42bpa: ENSMUSG00000026490

UniProt

Q5VT25

neXtProt

NX_Q5VT25

Human splice variants
Mouse splice variants