BS9192
antibody from Bioworld Technology, Inc
Targeting: CDC42BPA
FLJ23347, KIAA0451, MRCK, MRCKA, PK428
Antibody data
- Antibody Data
- Antigen structure
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- Validations [0]
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- Product number
- BS9192 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- MRCKÏ« (L663) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 634-687 of Human MRCKÏ«.
- Description
- Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Myotonic dystrophy kinase-related Cdc42-binding (DMPK-like) kinases-a and b (MRCK-a, b) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle myosin light chain and influences actin-myosin contractility (3,4). MRCK-a can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/cofilin and to Actin cytoskeletal reorganization. MRCK-a can also influence neurite outgrowth promoted by Cdc42 and Rac.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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