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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Product number
- ABIN493376 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Presenilin 1 (PSEN1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide corresponding to C-terminal of the Presenelin 1 protien. Remarks: The PSEN1-selective antibodies were generated against unique antigenicsequences form near N- and C-terminal peptides for the presenilin gene.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1-1.25 mg/ml (lot. specific)
- Storage
- Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Submitted references Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation.
Caspase cleaved presenilin-1 is part of active gamma-secretase complexes.
Cai D, Netzer WJ, Zhong M, Lin Y, Du G, Frohman M, Foster DA, Sisodia SS, Xu H, Gorelick FS, Greengard P
Proceedings of the National Academy of Sciences of the United States of America 2006 Feb 7;103(6):1941-6
Proceedings of the National Academy of Sciences of the United States of America 2006 Feb 7;103(6):1941-6
Caspase cleaved presenilin-1 is part of active gamma-secretase complexes.
Hansson CA, Popescu BO, Laudon H, Cedazo-Minguez A, Popescu LM, Winblad B, Ankarcrona M
Journal of neurochemistry 2006 Apr;97(2):356-64
Journal of neurochemistry 2006 Apr;97(2):356-64
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