ABIN121548

antibody from antibodies-online

Targeting: PSEN1 AD3, FAD, PS1, S182

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN121548

Provider

antibodies-online

Product name

anti-Presenilin 1 (PSEN1) antibody

Antibody type

Polyclonal

Antigen

N-terminus peptide (amino acids 14-33) of presenilin-1

Reactivity

Human

Host

Goat

Vial size

0.1 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.

References

Submitted references

Widespread immunoreactivity of presenilin in neurons of normal and Alzheimer's disease brains: double-labeling immunohistochemical study.

Uchihara T, el Hachimi HK, Duyckaerts C, Foncin JF, Fraser PE, Levesque L, St George-Hyslop PH, Hauw JJ
Acta neuropathologica 1996 Oct;92(4):325-30

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Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

Kovacs DM, Fausett HJ, Page KJ, Kim TW, Moir RD, Merriam DE, Hollister RD, Hallmark OG, Mancini R, Felsenstein KM, Hyman BT, Tanzi RE, Wasco W
Nature medicine 1996 Feb;2(2):224-9

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Antibodies to presenilin proteins detect neurofibrillary tangles in Alzheimer's disease.

Murphy GM Jr, Forno LS, Ellis WG, Nochlin D, Levy-Lahad E, Poorkaj P, Bird TD, Jiang Z, Cordell B
The American journal of pathology 1996 Dec;149(6):1839-46

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.

Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, Tsuda T, Mar L, Foncin JF, Bruni AC, Montesi MP, Sorbi S, Rainero I, Pinessi L, Nee L, Chumakov I, Pollen D, Brookes A, Sanseau P, Polinsky RJ, Wasco W, Da Silva HA, Haines JL, Perkicak-Vance MA, Tanzi RE, Roses AD, Fraser PE, Rommens JM, St George-Hyslop PH
Nature 1995 Jun 29;375(6534):754-60