MA1-752

antibody from Invitrogen Antibodies
Targeting: PSEN1 AD3, FAD, PS1, S182
Provider product page for MA1-752

Antibody data

Product number
MA1-752 - Provider product page
Provider
Invitrogen Antibodies
Product name
Presenilin 1 Monoclonal Antibody (APS 18)
Antibody type
Monoclonal
Antigen
Synthetic peptide
Description
MA1-752 detects presenilin 1 protein (PS1) from mouse, rat, human, and nonhuman primate samples. No cross-reactivity is seen with presenilin 2. MA1-752 has successfully been used in immuno-fluorescence, immunocytochemistry, Western blot, immunoprecipitation, and ELISA procedures. By Western blot, this antibody detects an ~18 kDa protein representing PS1 CT (C-terminus fragment) and the ~46 kDa full-length PS1 from transfected SH-SY5Y cells. In 4% paraformaldehyde fixed N2a cells, MA1-752 showed endogenous PS1 staining in the Golgi and cellular vesicles. The MA1-752 immunogen is a synthetic peptide corresponding to residues C S(313) K Y N A E S T E R E S Q D T V A E N D D G(334) of humen PS1.
Reactivity
Human, Mouse, Rat
Host
Mouse
Isotype
IgG
Antibody clone number
APS 18
Vial size
200 µg
Concentration
1 mg/mL
Storage
-20°C, Avoid Freeze/Thaw Cycles
PSEN1 protein structure - MA1-752 shown in red.