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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 333711 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#333711, RRID:AB_2564605
- Product name
- PE/Cy7 anti-human CD85j (ILT2)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- CD85 is a group of Ig superfamily tansmembrane glycoproteins called Ig-Like Transcripts (ILTs) or Leukocyte Immunoglobulin-like Receptors (LIRs). CD85j is the 110kD member, known as ILT2, LIR1, or LILRB1, and MIR7. ILT2 structurally has four Ig domains and contains ITIMs in its cytoplasmic tail that provide inhibitory signals by recruiting SHP-1. ILT2 is found on the surface of B cells, plasma cells, dendritic cells, monocytes, subsets of NK and T cells. The ligands of ILT2 include a broad range of HLA-A, -B molecules, some HLA-C and HLA-G molecules, and the human cytomegalovirus UL18 protein.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Near infrared dye
- Antibody clone number
- GHI/75
- Vial size
- 25 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human peripheral blood lymphocytes were stained with CD85j (clone GHI/75) PE/Cy7 (filled histogram) or mouse IgG2b, κ PE/Cy7 isotype control (open histogram).
- Conjugate
- Near infrared dye
