LILRB1

gene product
CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7, PIR-B, PIRB
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Novus Biologicals
97 antibodies
R&D Systems
22 antibodies
OriGene
9 antibodies
Biorbyt
16 antibodies
Proteintech Group
1 antibody
Invitrogen Antibodies
34 antibodies
antibodies-online
195 antibodies
LifeSpan BioSciences, Inc.
77 antibodies
Abnova Corporation
6 antibodies
Abgent
1 antibody
BioLegend
23 antibodies
Creative Biolabs
29 antibodies
Acris Antibodies GmbH
9 antibodies
Aviva Systems Biology
1 antibody
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1 antibody
Miltenyi Biotec
16 antibodies
Abbexa
4 antibodies
St John's Laboratory
2 antibodies
MyBioSource
5 antibodies
RabMAbs
1 antibody
Creative Diagnostics
10 antibodies
eBioscience, An Affymetrix Company
9 antibodies
United States Biological
20 antibodies
Leading Biology
2 antibodies
MilliporeSigma / Merck KGaA
1 antibody