333704

antibody from BioLegend

Targeting: LILRB1 CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7, PIR-B, PIRB

Functional assay

Antibody data

Submit

Validation data

Product number: 333704 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#333704, RRID:AB_1089088
Product name: LEAF™ purified anti-human CD85j (ILT2) [GHI/75]
Antibody type: Monoclonal
Antigen: CD85j (ILT2)
Description: CD85 is a group of Ig superfamily tansmembrane glycoproteins called Ig-Like Transcripts (ILTs) or Leukocyte Immunoglobulin-like Receptors (LIRs). CD85j is the 110kD member, known as ILT2, LIR1, or LILRB1, and MIR7. ILT2 structurally has four Ig domains and contains ITIMs in its cytoplasmic tail that provide inhibitory signals by recruiting SHP-1. ILT2 is found on the surface of B cells, plasma cells, dendritic cells, monocytes, subsets of NK and T cells. The ligands of ILT2 include a broad range of HLA-A, -B molecules, some HLA-C and HLA-G molecules, and the human cytomegalovirus UL18 protein.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 500 µg
Concentration: 1 mg/ml
Storage: he antibody solution should be stored undiluted at 4 °C. This LEAF™ solution contains no preservative; handle under aseptic conditions.

LILRB1 protein structure - 333704 shown in red.