AMM03738G

antibody from Leading Biology

Targeting: LILRB1 CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7, PIR-B, PIRB

Western blot (Recommended by provider)

Antibody Data

Product number

AMM03738G

Provider

Leading Biology

Product name

LILRB1 Antibody (monoclonal) (M01)

Antibody type

Monoclonal

Description

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

3D3-1D12

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.