Tissue expression
Cell line expression
Protein structure
CDRT1
CMT1A duplicated region transcript 1FBXW10B, FBXW10P1, HREP, SM25H2
Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]). [supplied by OMIM, Mar 2008]
Top validated antibodies |
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Abnova Corporation | ![]() |
Polyclonal |
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St John's Laboratory | ![]() |
Polyclonal |
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MilliporeSigma / Merck KGaA | ![]() |
Polyclonal |
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