Antibody data
- Antibody Data
- Antigen structure
- References [380]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11064-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11064-1-AP, RRID:AB_2195801
- Product name
- SOX2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SOX2 antibody (Cat. #11064-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, zebrafish and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Zebrafish
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Co-targeting MRPS7-23 synergistically enhances cisplatin efficacy to suppress nasopharyngeal carcinoma growth and metastasis.
SHP2 improved Late-onset fetal growth restriction via modulating ROS/BRD4/PI3K/YAP/PIGF signaling induced angiogenesis.
Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation.
Brain-Targeted RVG-Liposomal Melatonin Ameliorates Manganese Neurotoxicity by Enhancing Neurogenesis and Modulating Systemic Amino Acid Profiles.
Schisantherin A promotes neural differentiation of stem cells from apical papilla to improve mandibular development via mental nerve repair.
Weiyan Tongluo Granules attenuate gastric intestinal metaplasia through PPARγ/NF-κB/CDX2 signaling pathway.
H3K9me2 is a determinant for the mitosis-to-meiosis transition in female germ cells.
Pseudoginsenoside F11 enhances YBX1-mediated transcriptional repression of PRPS2 to inhibit the stemness and pulmonary metastasis of triple- negative breast cancer.
Functional and metabolic dysbiosis of the gut microbiome in the tumoral immune microenvironment of hepatocellular carcinoma.
Adipose-derived stem cells (ADSCs)-derived DKK1 promotes cutaneous wound healing by inducing M2 macrophage polarization via PI3K/AKT and JNK activation.
CNOT3 resists ovarian aging by accelerating oocyte maturation and promoting ESCs differentiation.
Precise excision of expanded GGC repeats in NOTCH2NLC via CRISPR/Cas9 for treating neuronal intranuclear inclusion disease.
Wnt/β-Catenin Activation by iCRT3 Enhanced the Pluripotency of Bovine Expanded Pluripotent Stem Cells.
HSPA5 promotes YAP/TAZ stability independently of the Hippo pathway and induces proneural-to-mesenchymal transition in glioblastoma.
Integrated single-cell and spatial transcriptomic profiling decodes lineage plasticity and immune microenvironment remodeling in prostate cancer progression.
Taurine attenuates arsenic-induced neurotoxicity through modulation of gut microbiota structure.
The GOLM1-ACLY pathway regulates macrophage-secreted EFEMP1 via H3K27ac modifications to drive tumor progression.
Recombinant Filaggrin-2 microneedles reverse androgenetic alopecia by rescuing mitochondrial dysfunction in dermal papilla cells.
Microalgae-MOF integrated drug delivery system for cranial radiotherapy and chemotherapy-induced brain injury.
HSP90AB1-Mediated Ubiquitin-Proteasome Degradation of ITGBL1 Promotes Osteosarcoma Progression by Inhibiting Endoplasmic Reticulum Stress-Induced Autophagy.
OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17-Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC.
Discovery, Optimization, and Biological Evaluation of 2-Cyano-2-(9H-xanthen-9-ylidene)acetamide Derivatives as ZNF207 Inhibitors for Anti-Glioma Therapy.
Nuclear N-glycosylation maintains H3K9me3 heterochromatin and genomic stability.
KRT15 identified by scRNA-Seq and machine learning as stemness regulator and prognostic biomarker in ESCC.
Generating Microglia-Integrated Cortical Organoids from Human Embryonic Stem Cells.
Hyperthermia Inhibits Growth and Stemness of Esophageal Squamous Cell Carcinoma Cells Through Promoting Degradation of GLI1.
Comprehensive Bioinformatics Analysis and Validation of the Mechanism of Glutamic-pyruvic Transaminase 2 in Bladder Cancer.
Comprehensive analysis of IGFL1 in colorectal cancer and its promotion of tumour progression via inhibition of lipophagy.
A novel pathway for stemness propagation and chemoresistance in non-small cell lung cancer via phosphorylated PKM2-loaded small extracellular vesicles.
Establishment of an induced pluripotent stem cell (iPSC) line (INNDSUi011-A) from a patient with autosomal dominant spastic paraplegia 9A due to ALDH18A1 mutation.
Daughter Cells Budding From PGCCs and Their Clinicopathological Significances in Oral Squamous Cell Carcinoma.
Genipin stabilized fibrin microbeads: Carrying cytokines to form niches for stem cell differentiation.
Myogenic induced adipose-derived stem cells sheets combined with electrospun scaffolds of silk fibroin and poly(lactide-co-glycolide) for stress urinary incontinence treatment.
Transplanting neural stem cells overexpressing miRNA-21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28-let-7 signaling pathway.
CROT overactivation within peroxisomes confers chemoresistance to non-small cell lung cancer by targeting fatty acid oxidation-Nrf2-ferroptosis resistance axis.
Breaking the link between morphology and potency for mESCs.
PNO1 served as a potential biomarker to promote the stemness and progression of breast cancer via the NF-κB signaling pathway.
Histone Lactylation-Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells.
Investigating the impact of MCTP2 on immune suppression and drug resistance in glioblastoma.
Ethylene Glycol and Trehalose Cryopreservation of Cell-Laden Hydrogel Microspheres Enabled by Microfluidic Fabrication.
Ginsenoside Rh2 as a novel PIN1 inhibitor disrupting the cancer stem cell-like phenotype in non-small cell lung cancer.
A new protocol for the development of organoids based on molecular mechanisms in the developing newborn rat brain: Prospective applications in the study of Alzheimer's disease.
Neuroprotective Effects of Qi Jing Wan and Its Active Ingredient Diosgenin Against Cognitive Impairment in Plateau Hypoxia.
NSUN4 Facilitates the Activity of Oncogenic Protein CDC20 to Promote NSCLC Development by Mediating m5C Modification of CDC20 mRNA.
GNE-317 Reverses MSN-Mediated Proneural-to-Mesenchymal Transition and Suppresses Chemoradiotherapy Resistance in Glioblastoma via PI3K/mTOR.
RNA-binding protein SAMD4A targets FGF2 to regulate cardiomyocyte lineage specification from human embryonic stem cells.
Identification of a non-inhibitory aptameric ligand to CRL2(ZYG11B) E3 ligase for targeted protein degradation.
The asymmetric expression of HSPA2 in blastomeres governs the first embryonic cell-fate decision.
Generation of an induced pluripotent stem cell (iPSC) line (INNDSUi009-A) from a patient with amyotrophic lateral sclerosis due to SOD1 mutation.
Conjugated therapy with coaxially printed neural stem cell-laden microfibers and umbilical cord mesenchymal stem cell derived exosomes on complete transactional spinal cord defects.
Vegfr3 activation of Pkd2l1(+) CSF-cNs triggers the neural stem cell response in spinal cord injury.
Analysis of astrocyte progenitors derived from human induced pluripotent stem cells in vitro and following transplantation into the intact spinal cord.
Identification of the Oncogenic Role of MSH2 in the Stemness and Progression of Glioma Through Regulating Wnt Signaling Pathway.
Melatonin as an Alleviator in Decabromodiphenyl Ether-Induced Aberrant Hippocampal Neurogenesis and Synaptogenesis: The Role of Wnt7a.
NKD1 enhances colon cancer progression by inhibiting the autophagic degradation of MYC.
Wnt5a promotes VM formation by modulating the stemness and EMT progression of prostate cancer cell.
Tetramethylpyrazine attenuates the cancer stem cell like-properties and doxorubicin resistance by targeting HMGCR in breast cancer.
Supervillin-Mediated ZO-1 Downregulation Facilitates Migration of Cisplatin-Resistant HCT116 Colorectal Cancer Cells.
TC2N maintains stem cell-like characteristics to accelerate lung carcinogenesis by blockade of dual specificity protein phosphatase 3.
Nitric Oxide-Releasing Mesoporous Hollow Cerium Oxide Nanozyme-Based Hydrogel Synergizes with Neural Stem Cell for Spinal Cord Injury Repair.
Dual-phase nanoscissors disrupt vasculature-breast cancer stem cell crosstalk for breast cancer treatment.
Generation of an induced pluripotent stem cell (iPSC) line (INNDSUi007-A) from a patient with Kennedy disease.
Long non-coding RNA MIR4435-2HG modulates pancreatic cancer stem cells and chemosensitivity to gemcitabine by targeting the miR-1252-5p/STAT1.
Mesenchymal stem cells overexpressing neuropeptide S promote the recovery of rats with spinal cord injury by activating the PI3K/AKT/GSK3β signaling pathway.
Enhanced or reversible RNA N6-methyladenosine editing by red/far-red light induction.
Effects of mesenchymal stem cells from different sources on the biological functions of multiple myeloma cells.
Low-intensity pulsed ultrasound promotes proliferation and differentiation of neural stem cells to enhance spinal cord injury recovery.
Rack1 promotes breast cancer stemness properties and tumorigenesis through the E2F1-SOX2 axis.
The PLEKHA1-TACC2 fusion gene drives tumorigenesis via vascular mimicry formation in esophageal squamous-cell carcinoma.
Lactate mitochondrial oxidation drives stemness potential in metastatic breast cancer.
Machine learning-based identification of kbhb-affected tumor cell subsets as prognostic and therapeutic targets in breast cancer.
Valproic acid boosts hair follicle stem cell resilience to oxygen-glucose deprivation through autophagy induction and AKT/mTOR suppression.
SETD5 facilitates stemness and represses ferroptosis via m6A-mediating PKM2 stabilization in non-small cell lung cancer.
The combination of FLI, ITS, pFF, and citrate improves the developmental potential of gilt oocytes during in vitro maturation.
Hydroxysafflor yellow A promotes the proliferation and differentiation of endogenous neural stem cells with neural regenerative effects in ischemic stroke.
NR2F2 and its contribution to lymph node metastasis in oral squamous cell carcinoma.
Mesenchymal stem cell-derived lncRNAs NKILA contributes to stemness and chemoresistance by fatty acid oxidation in gastric cancer via miR-485-5p/STAT3.
Generation of an induced pluripotent stem cell (iPSC) line (INNDSUi008-A) from a patient with Spinocerebellar Ataxia Type 3.
N4-Acetylcytidine-Mediated CD2BP2-DT Drives YBX1 Phase Separation to Stabilize CDK1 and Promote Breast Cancer Progression.
Lipopolysaccharide Induces Resistance to CAR-T Cell Therapy of Colorectal Cancer Cells through TGF-β-Mediated Stemness Enhancement.
Ara-C suppresses H3 K27-altered spinal cord diffuse midline glioma growth and enhances immune checkpoint blockade sensitivity.
3D mesenchymal stem cell exosome-functionalized hydrogels for corneal wound healing.
A Hybrid Manganese Nanoparticle Simultaneously Eliminates Cancer Stem Cells and Activates STING Pathway to Potentiate Cancer Immunotherapy.
ΔNp63α promotes cigarette smoke-induced renal cancer stem cell activity via the Sonic Hedgehog pathway.
VEGFA/NRP-1/GAPVD1 axis promotes progression and cancer stemness of triple-negative breast cancer by enhancing tumor cell-macrophage crosstalk.
KYNU Expression Promotes Cisplatin Resistance in Esophageal Cancer.
Identification of hub genes within the CCL18 signaling pathway in hepatocellular carcinoma through bioinformatics analysis.
Strategic targeting of miR-183 and β-catenin to enhance BMSC stemness in age-related osteoporosis therapy.
Integrated machine learning algorithms identify KIF15 as a potential prognostic biomarker and correlated with stemness in triple-negative breast cancer.
USP14 promotes the cancer stem-like cell properties of OSCC via promoting SOX2 deubiquitination.
METTL3 inhibitor suppresses the progression of prostate cancer via IGFBP3/AKT pathway and synergizes with PARP inhibitor.
The effects of BMP2 and the mechanisms involved in the invasion and angiogenesis of IDH1 mutant glioma cells.
Chronic lung inflammation and CK14+ basal cell proliferation induce persistent alveolar-bronchiolization in SARS-CoV-2-infected hamsters.
Construction of a lung cancer 3D culture model based on alginate/gelatin micro-beads for drug evaluation.
TRIB3 inhibition by palbociclib sensitizes prostate cancer to ferroptosis via downregulating SOX2/SLC7A11 expression.
The role and mechanism of NRG1/ErbB4 in inducing the differentiation of induced pluripotent stem cells into cardiomyocytes.
Combining single-cell profiling and functional analysis explores the role of pseudogenes in human early embryonic development.
Anti-Stress and Anti-ROS Effects of MnOx-Functionalized Thermosensitive Nanohydrogel Protect BMSCs for Intervertebral Disc Degeneration Repair.
iPSC-derived NK cells with site-specific integration of CAR19 and IL24 at the multi-copy rDNA locus enhanced antitumor activity and proliferation.
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages.
α5-nAChR/ADAM10 signaling mediates nicotine-related cutaneous melanoma progression via STAT3 activation.
GFP-labeled Schwann cell-like cells derived from hair follicle epidermal neural crest stem cells promote the acellular nerve allografts to repair facial nerve defects in rats.
1-Benzylimidazole attenuates the stemness of breast cancer cells through partially targeting CYP4Z1.
LncRNA linc01194 promotes the progress of endometrial carcinoma by up-regulating SOX2 through binding to IGF2BP1.
OTUD7B knockdown inhibits the proliferation and stemness of breast cancer cells by destabilizing FOXM1.
Hapln1 promotes dedifferentiation and proliferation of iPSC-derived cardiomyocytes by promoting versican-based GDF11 trapping.
Hinokitiol Inhibits Breast Cancer Cells In Vitro Stemness-Progression and Self-Renewal with Apoptosis and Autophagy Modulation via the CD44/Nanog/SOX2/Oct4 Pathway.
Establishment of an induced pluripotent stem cell (iPSC) line (INNDSUi004-A) from a patient with Congenital Nemaline Myopathy.
Generation of a control induced pluripotent stem cell line (SDUCHi001-A) from a healthy male donor.
Establishment of an induced pluripotent stem cell (iPSC) line (INNDSUi005-A) from a healthy female Chinese Han.
The small nucleolar RNA SNORA51 enhances breast cancer stem cell-like properties via the RPL3/NPM1/c-MYC pathway.
Cysteine and glycine-rich protein 2 is crucial for maintaining the malignant phenotypes of gliomas through its action on Notch signalling cascade.
Clinicopathological significance of cancer stem cell marker CD44/SOX2 in esophageal squamous cell carcinoma (ESCC) patients and construction of a nomogram to predict overall survival.
GD2 and its biosynthetic enzyme GD3 synthase promote tumorigenesis in prostate cancer by regulating cancer stem cell behavior.
Superb Silk Hydrogels with High Adaptability, Bioactivity, and Versatility Enabled by Photo-Cross-Linking.
Huaier enhances the tumor-killing effect and reverses gemcitabine-induced stemness by suppressing FoxM1.
Identification of signaling pathways that specify a subset of migrating enteric neural crest cells at the wavefront in mouse embryos.
TAX1BP1 and FIP200 orchestrate non-canonical autophagy of p62 aggregates for mouse neural stem cell maintenance.
The demethylase ALKBH5 mediates ZKSCAN3 expression through the m(6)A modification to activate VEGFA transcription and thus participates in MNNG-induced gastric cancer progression.
TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis.
PKCiota Inhibits the Ferroptosis of Esophageal Cancer Cells via Suppressing USP14-Mediated Autophagic Degradation of GPX4.
Prolonged exposure of environmental concentration benzo[a]pyrene promoted cancer stemness through AhR/PKA/SOX2 dependent pathway in small cell lung cancer.
Epigenetic inhibition of CTCF by HN1 promotes dedifferentiation and stemness of anaplastic thyroid cancer.
Exosomal circ_0037104 derived from Hu-MSCs inhibits cholangiocarcinoma progression by sponging miR-620 and targeting AFAP1.
Tumor suppressor miR-361-3p inhibits prostate cancer progression through Gli1 and AKT/mTOR signaling pathway.
EBF1 Limits the Numbers of Cochlear Hair and Supporting Cells and Forms the Scala Tympani and Spiral Limbus during Inner Ear Development.
Generation of the TSHSUi002-A induced pluripotent stem cell line from a patient with Peutz-Jeghers syndrome carring STK11 gene mutation.
Six induced pluripotent stem cell lines from fibroblasts of individuals with CLN3-related conditions.
Fibroblast growth factor 2 enhances BMSC stemness through ITGA2-dependent PI3K/AKT pathway activation.
Comprehensive gene set enrichment and variation analyses identify SUV39H1 as a potential prognostic biomarker for glioblastoma immunorelevance.
Phytosesquiterpene lactones deregulate mitochondrial activity and phenotypes associated with triple-negative breast cancer metastasis.
CENPA facilitates glioma stem cell stemness and suppress ferroptosis to accelerate glioblastoma multiforme progression by promoting GBP2 transcription.
Digirseophene A promotes recovery in injured developing cerebellum via AMPK/AKT/GSK3β pathway-mediated neural stem cell proliferation.
Microbial reconstitution reverses prenatal stress-induced cognitive impairment and synaptic deficits in rat offspring.
Identifying polyamine related biomarkers in diagnosis and treatment of ulcerative colitis by integrating bulk and single-cell sequencing data.
OTU deubiquitinase, ubiquitin aldehyde binding 2 (OTUB2) modulates the stemness feature, chemoresistance, and epithelial-mesenchymal transition of colon cancer via regulating GINS complex subunit 1 (GINS1) expression.
Unveiling the role of TAGLN2 in glioblastoma: From proneural-mesenchymal transition to Temozolomide resistance.
Biomineralization-Tuned Nanounits Reprogram the Signal Transducer and Activator of Transcription 3 Signaling for Ferroptosis-Immunotherapy in Cancer Stem Cells.
M6A-methylated circPOLR2B forms an R-loop and regulates the biological behavior of glioma stem cells through positive feedback loops.
N-linked α2,6-sialylation of integrin β1 by the sialyltransferase ST6Gal1 promotes cell proliferation and stemness in gestational trophoblastic disease.
The Natural Product Secoemestrin C Inhibits Colorectal Cancer Stem Cells via p38-S100A8 Feed-Forward Regulatory Loop.
GD2 and its biosynthetic enzyme GD3 synthase promote tumorigenesis in prostate cancer by regulating cancer stem cell behavior.
The Role of Purine Metabolism-Related Genes PPAT and IMPDH1 in the Carcinogenesis of Intrahepatic Cholangiocarcinoma Based on Metabonomic and Bioinformatic Analyses.
Extracellular vesicles carrying miR-6836 derived from resistant tumor cells transfer cisplatin resistance of epithelial ovarian cancer via DLG2-YAP1 signaling pathway.
Characterization of immature ovarian teratomas through single-cell transcriptome.
Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study.
NPM1 promotes nasopharyngeal carcinoma metastasis and stemness by recruiting Mdm2 to induce the ubiquitination-mediated degradation of p53.
MOGS promotes stemness acquisition and invasion via enhancing NOTCH1-glycosylation dependent NOTCH pathway in colorectal cancer.
YAP1 affects the prognosis through the regulation of stemness in endometrial cancer.
Generation of an iPSC line (TSHSUi001-A) from a patient with Peutz-Jeghers syndrome due to STK11 mutation.
LncRNA PVT1 promotes strong stemness and endothelial progenitor cell characteristics in renal carcinoma stem cells.
A novel TOX3-WDR5-ABCG2 signaling axis regulates the progression of colorectal cancer by accelerating stem-like traits and chemoresistance.
METTL3-stabilized super enhancers-lncRNA SUCLG2-AS1 mediates the formation of a long-range chromatin loop between enhancers and promoters of SOX2 in metastasis and radiosensitivity of nasopharyngeal carcinoma.
Glioma-derived small extracellular vesicles induce pericyte-phenotype transition of glioma stem cells under hypoxic conditions.
DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress.
Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice.
Biomimetic Microenvironmental Stiffness Boosts Stemness of Pancreatic Ductal Adenocarcinoma via Augmented Autophagy.
Generation of an induced pluripotent stem cell line (SDASi001-A) from a Schimke immune-osseous dysplasia patient with SMARCAL1 mutations.
Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer.
IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification.
Fabrication of a Three-Dimensional Spheroid Culture System for Oral Squamous Cell Carcinomas Using a Microfabricated Device.
ADP Ribosylation Factor 4 (Arf4) Regulates Radial Migration through N-Cadherin Trafficking during Cerebral Cortical Development.
Histone lactylation-derived LINC01127 promotes the self-renewal of glioblastoma stem cells via the cis-regulating the MAP4K4 to activate JNK pathway.
m6A modified BACE1-AS contributes to liver metastasis and stemness-like properties in colorectal cancer through TUFT1 dependent activation of Wnt signaling.
Inhibiting MEK1 R189 citrullination enhances the chemosensitivity of docetaxel to multiple tumour cells.
From Hair to the Brain: The Short-Term Therapeutic Potential of Human Hair Follicle-Derived Stem Cells and Their Conditioned Medium in a Rat Model of Stroke.
Nobiletin Mitigates D-Galactose-Induced Memory Impairment via Improving Hippocampal Neurogenesis in Mice.
CircNFIX stimulates the proliferation, invasion, and stemness properties of ovarian cancer cells by enhancing SH3RF3 mRNA stability via binding LIN28B.
Neuroprotective effects of neural stem cells pretreated with neuregulin1β on PC12 cells exposed to oxygen-glucose deprivation/reoxygenation.
EGFRvIII Promotes the Proneural-Mesenchymal Transition of Glioblastoma Multiforme and Reduces Its Sensitivity to Temozolomide by Regulating the NF-κB/ALDH1A3 Axis.
Transgelin promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release.
Generation of an induced pluripotent stem cell (iPSC) line (INNDSUi002-A) from a patient with riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency.
MicroRNA26a Overexpression Hastens Osteoblast Differentiation Capacity in Dental Stem Cells.
MED27 plays a tumor-promoting role in breast cancer progression by targeting KLF4.
SLC1A5 regulates cell proliferation and self-renewal through β-catenin pathway mediated by redox signaling in arsenic-treated uroepithelial cells.
HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.
Plasmalogen Improves Memory Function by Regulating Neurogenesis in a Mouse Model of Alzheimer's Diseases.
Induced neural stem cells suppressed neuroinflammation by inhibiting the microglial pyroptotic pathway in intracerebral hemorrhage rats.
Ginsenoside Rg1 promotes astrocyte-to-neuron transdifferentiation in rat and its possible mechanism.
Isolation of Swine Bone Marrow Lin-/CD45-/CD133 + Cells and Cardio-protective Effects of its Exosomes.
The Adipokine Visfatin Modulates Cancer Stem Cell Properties in Triple-Negative Breast Cancer.
Core-shell SERS nanotags-based western blot.
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
USP10 promotes intrahepatic cholangiocarcinoma cell survival and stemness via SNAI1 deubiquitination.
Astragaloside IV enhances the sensitivity of breast cancer stem cells to paclitaxel by inhibiting stemness.
α5-nAChR/STAT3/CD47 axis contributed to nicotine-related lung adenocarcinoma progression and immune escape.
IL20RB signaling enhances stemness and chemotherapy resistance in pancreatic cancer.
Metformin promotes cGAS/STING signaling pathway activation by blocking AKT phosphorylation in gastric cancer.
USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.
KIF15 knockdown inhibits the development of endometrial cancer by suppressing epithelial-mesenchymal transition and stemness through Wnt/β-catenin signaling.
B7-H3 confers stemness characteristics to gastric cancer cells by promoting glutathione metabolism through AKT/pAKT/Nrf2 pathway.
NeuroD4 converts glioblastoma cells into neuron-like cells through the SLC7A11-GSH-GPX4 antioxidant axis.
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Palmitoyl transferases act as novel drug targets for pancreatic cancer.
Metformin Promotes the Hair-Inductive Activity of Three-Dimensional Aggregates of Epidermal and Dermal Cells Self-Assembled in vitro.
Antitumor Effect of Si-Jun-Zi Decoction on SGC7901 Gastric Cancer Cells by CMTM2 Activation.
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.
Selected Histone Deacetylase Inhibitors Reverse the Frataxin Transcriptional Defect in a Novel Friedreich's Ataxia Induced Pluripotent Stem Cell-Derived Neuronal Reporter System.
Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model.
LASS2 impairs proliferation of glioma stem cells and migration and invasion of glioma cells mainly via inhibition of EMT and apoptosis promotion.
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling.
Prrx1 promotes resistance to temozolomide by upregulating ABCC1 and inducing vasculogenic mimicry in glioma.
hsa_circ_0001741 promotes esophageal squamous cell carcinoma stemness, invasion and migration by sponging miR-491-5p to upregulate NOTCH3 expression.
Lgr5(+) cells are required and dynamically participate in olfactory epithelium regeneration: a revisiting shows Lgr5 expression in multiple cell lineages.
ISG15 enhances glioma cell stemness by promoting Oct4 protein stability.
ΔNp63α mediates sulforaphane suppressed colorectal cancer stem cell properties through transcriptional regulation of Nanog/Oct4/Sox2.
High-efficiency brain-targeted intranasal delivery of BDNF mediated by engineered exosomes to promote remyelination.
miR-124- and let-7-Mediated Reprogram of Human Fibroblasts into SST Interneurons.
GDF15 Contributes to Radioresistance by Mediating the EMT and Stemness of Breast Cancer Cells.
CAFs-secreted exosomal cricN4BP2L2 promoted colorectal cancer stemness and chemoresistance by interacting with EIF4A3.
Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer.
PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop.
Long non-coding RNA NRSN2-AS1, transcribed by SOX2, promotes progression of esophageal squamous cell carcinoma by regulating the ubiquitin-degradation of PGK1.
Rspondin-1 contributes to the progression and stemness of gastric cancer by LGR5.
Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer.
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
A three-dimensional matrix system containing melatonin and neural stem cells repairs damage from traumatic brain injury in rats.
FAM64A promotes HNSCC tumorigenesis by mediating transcriptional autoregulation of FOXM1.
Claudin1 decrease induced by 1,25-dihydroxy-vitamin D3 potentiates gefitinib resistance therapy through inhibiting AKT activation-mediated cancer stem-like properties in NSCLC cells.
Transplantation of Human Umbilical Cord Mesenchymal Stem Cells-Derived Neural Stem Cells Pretreated with Neuregulin1β Ameliorate Cerebral Ischemic Reperfusion Injury in Rats.
Poly(I:C) exposure during in vitro fertilization disrupts first cleavage of mouse embryos and subsequent blastocyst development.
A novel ALG10/TGF-β positive regulatory loop contributes to the stemness of colorectal cancer.
SNAT2/SLC38A2 Confers the Stemness of Gastric Cancer Cells via Regulating Glutamine Level.
Generation of human induced pluripotent stem cell line from peripheral blood mononuclear cells from an activated phosphoinositide 3-kinase δ syndrome patient.
Establishment of an induced pluripotent stem cell (iPSC) line (INNDSUi001-A) from a healthy female Chinese Han.
Generation of a human induced pluripotent stem cell line (INNDSUi003-A) derived from patient with Becker muscular dystrophy (BMD).
miR-3682-3p directly targets FOXO3 and stimulates tumor stemness in hepatocellular carcinoma via a positive feedback loop involving FOXO3/PI3K/AKT/c-Myc.
Expansion of mouse castration-resistant intermediate prostate stem cells in vitro.
tRF-19-W4PU732S promotes breast cancer cell malignant activity by targeting inhibition of RPL27A (ribosomal protein-L27A).
Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer.
Endothelial cell-derived S1P promotes migration and stemness by binding with GPR63 in colorectal cancer.
ALG2 inhibits the epithelial-to-mesenchymal transition and stemness of ovarian granulosa cells through the Wnt/β-catenin signaling pathway in polycystic ovary syndrome.
Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization.
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
CRISPR/Cas9-mediated genetic correction reverses spinocerebellar ataxia 3 disease-associated phenotypes in differentiated cerebellar neurons.
Inhibitory effect of the novel tyrosine kinase inhibitor DCC-2036 on triple-negative breast cancer stem cells through AXL-KLF5 positive feedback loop.
Neural, adipocyte and hepatic differentiation potential of primary and secondary hair follicle stem cells isolated from Arbas Cashmere goats.
CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma.
Establishment of iPS cell line (KLRMMEi002-A) by reprogramming peripheral blood mononuclear cells from a patient with USH2A-associated Usher syndrome.
MicroRNA-18 facilitates the stemness of gastric cancer by downregulating HMGB3 though targeting Meis2.
SNORD1C maintains stemness and 5-FU resistance by activation of Wnt signaling pathway in colorectal cancer.
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis.
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.
Blockade of deubiquitinating enzyme PSMD14 overcomes chemoresistance in head and neck squamous cell carcinoma by antagonizing E2F1/Akt/SOX2-mediated stemness.
IL20RA signaling enhances stemness and promotes the formation of an immunosuppressive microenvironment in breast cancer.
Regulatory T cells promote glioma cell stemness through TGF-β-NF-κB-IL6-STAT3 signaling.
TAZ inhibits acinar cell differentiation but promotes immature ductal cell proliferation in adult mouse salivary glands.
Activation of bivalent factor DLX5 cooperates with master regulator TP63 to promote squamous cell carcinoma.
An SETD1A/Wnt/β-catenin feedback loop promotes NSCLC development.
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Immunohistochemical evidence for adult human neurogenesis in health and disease.
MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal.
An iPS cell line SDUBMSi0011-A from a multiple epiphyseal dysplasia patient carrying c. 1076T > G mutation in the SMOC2 gene.
Generation of an induced pluripotent stem cell line SDUBMSi005-A from a patient with double primary gastric and colon carcinoma.
Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability.
CDR1as regulated by hnRNPM maintains stemness of periodontal ligament stem cells via miR-7/KLF4.
Apatinib suppresses lung cancer stem-like cells by complex interplay between β-catenin signaling and mitochondrial ROS accumulation.
Establishment of patient-specific induced pluripotent stem cell line SDUBMSi009-A from a patient with X-linked Lowe syndrome.
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation.
NRF2 is required for structural and metabolic maturation of human induced pluripotent stem cell-derived ardiomyocytes.
p97/VCP is highly expressed in the stem-like cells of breast cancer and controls cancer stemness partly through the unfolded protein response.
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
SMAR1 attenuates the stemness of osteosarcoma cells via through suppressing ABCG2 transcriptional activity.
Chitinase-Like Protein Ym2 (Chil4) Regulates Regeneration of the Olfactory Epithelium via Interaction with Inflammation.
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
The stemness of hepatocytes is maintained by high levels of lipopolysaccharide via YAP1 activation.
The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis.
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Polychlorinated biphenyl quinone induced the acquisition of cancer stem cells properties and epithelial-mesenchymal transition through Wnt/β-catenin.
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
A novel regulatory loop miR-101/ANXA2/EGR1 mediates malignant characteristics of liver cancer stem cells.
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
SETD8 induces stemness and epithelial-mesenchymal transition of pancreatic cancer cells by regulating ROR1 expression.
Alterations of DNA methylation were associated with the rapid growth of cortisol-producing adrenocortical adenoma during pregnancy.
Lysosome Fe(2+) release is responsible for etoposide- and cisplatin-induced stemness of small cell lung cancer cells.
DEAD-box helicase 27 enhances stem cell-like properties with poor prognosis in breast cancer.
Generation and characterization of an integration-free iPSC line SDUBMSi006-A from a patient with Alport syndrome caused by COL4A3 gene mutations.
5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells.
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.
Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features.
Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development.
The F-box protein FBXO11 restrains hepatocellular carcinoma stemness via promotion of ubiquitin-mediated degradation of Snail.
SULT4A1 Modulates Synaptic Development and Function by Promoting the Formation of PSD-95/NMDAR Complex.
Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target.
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Bufalin attenuates triple-negative breast cancer cell stemness by inhibiting the expression of SOX2/OCT4.
Nucleotide de novo synthesis increases breast cancer stemness and metastasis via cGMP-PKG-MAPK signaling pathway.
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
The miRNA-149-5p/MyD88 axis is responsible for ursolic acid-mediated attenuation of the stemness and chemoresistance of non-small cell lung cancer cells.
Bisphenol A and polychlorinated biphenyls enhance the cancer stem cell properties of human ovarian cancer cells by activating the WNT signaling pathway.
Generation of a human induced pluripotent stem cell line (SDUBMSi001-A) from a hereditary spastic paraplegia patient carrying kif1a c.773C>T missense mutation.
Generation of patient-specific pluripotent induced stem cell line SDUBMSI002-A from a patient with X-linked mental retardation syndrome.
LncRNA-cCSC1 modulates cancer stem cell properties in colorectal cancer via activation of the Hedgehog signaling pathway.
Inhibition of PIM1 attenuates the stem cell-like traits of breast cancer cells by promoting RUNX3 nuclear retention.
MCF7 Spheroid Development: New Insight about Spatio/Temporal Arrangements of TNTs, Amyloid Fibrils, Cell Connections, and Cellular Bridges.
Zinc Promotes Patient-Derived Induced Pluripotent Stem Cell Neural Differentiation via ERK-STAT Signaling.
Generation of an iPSC line (HUSTi002-A) from fibroblasts of a patient with Sertoli cell-only syndrome carrying c.731_732delAT in PIWIL2 gene.
Chlorogenic acid inhibits esophageal squamous cell carcinoma growth in vitro and in vivo by downregulating the expression of BMI1 and SOX2.
Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer.
Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells.
CMIP promotes Herceptin resistance of HER2 positive gastric cancer cells.
MicroRNA‑487b‑3p inhibits osteosarcoma chemoresistance and metastasis by targeting ALDH1A3.
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis.
LIPH promotes metastasis by enriching stem-like cells in triple-negative breast cancer.
The Effects of Daxx Knockout on Pluripotency and Differentiation of Mouse Induced Pluripotent Stem Cells.
WIP1 promotes cancer stem cell properties by inhibiting p38 MAPK in NSCLC.
Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat.
Microenvironment Can Induce Development of Auditory Progenitor Cells from Human Gingival Mesenchymal Stem Cells.
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
COL4A2 in the tissue-specific extracellular matrix plays important role on osteogenic differentiation of periodontal ligament stem cells.
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Limbal niche cells can reduce the angiogenic potential of cultivated oral mucosal epithelial cells.
Modeling Retinitis Pigmentosa: Retinal Organoids Generated From the iPSCs of a Patient With the USH2A Mutation Show Early Developmental Abnormalities.
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma.
Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway.
Six1 is negatively correlated with poor prognosis and reduces 5-fluorouracil sensitivity via attenuating the stemness of hepatocellular carcinoma cells.
N-acetylcysteine alleviated paraquat-induced mitochondrial fragmentation and autophagy in primary murine neural progenitor cells.
Pre-metastatic niche triggers SDF-1/CXCR4 axis and promotes organ colonisation by hepatocellular circulating tumour cells via downregulation of Prrx1.
A small molecule Hedgehog agonist HhAg1.5 mediated reprogramming breaks the quiescence of noninjured liver stem cells for rescuing liver failure.
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.
Chondroitin sulfate proteoglycan represses neural stem/progenitor cells migration via PTPσ/α-actinin4 signaling pathway.
In vivo tracking on longer retention of transplanted myocardin gene-modified adipose-derived stem cells to improve erectile dysfunction in diabetic rats.
G protein-coupled estrogen receptor 1 negatively regulates the proliferation of mouse-derived neural stem/progenitor cells via extracellular signal-regulated kinase pathway.
Downregulation of DAPK1 promotes the stemness of cancer stem cells and EMT process by activating ZEB1 in colorectal cancer.
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
Bruceine D inhibits tumor growth and stem cell-like traits of osteosarcoma through inhibition of STAT3 signaling pathway.
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Targeting Hyaluronan Interactions for Glioblastoma Stem Cell Therapy.
Stabilized Peptide HDAC Inhibitors Derived from HDAC1 Substrate H3K56 for the Treatment of Cancer Stem-Like Cells In Vivo.
Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation.
Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma.
Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19.
The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway.
FBXW7 suppresses epithelial-mesenchymal transition and chemo-resistance of non-small-cell lung cancer cells by targeting snai1 for ubiquitin-dependent degradation.
Expression patterns of Rbm24 in lens, nasal epithelium, and inner ear during mouse embryonic development.
Knockdown of Sox2 Inhibits OS Cells Invasion and Migration via Modulating Wnt/β-Catenin Signaling Pathway.
Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury.
TRPV4 Activation Contributes Functional Recovery from Ischemic Stroke via Angiogenesis and Neurogenesis.
Generation of an iPS cell line via a non-integrative method using urine-derived cells from a patient with USH2A-associated retinitis pigmentosa.
Directing Induced Pluripotent Stem Cell Derived Neural Stem Cell Fate with a Three-Dimensional Biomimetic Hydrogel for Spinal Cord Injury Repair.
The ubiquitin ligase SCF(FBXW7α) promotes GATA3 degradation.
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
The three branches of the unfolded protein response exhibit differential significance in breast cancer growth and stemness.
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
[Impact of Cystic Fibrosis Transmembrane Conductance Regulator on Malignant Properties of KRAS Mutant Lung Adenocarcinoma A549 Cells].
Neuralized1a regulates asymmetric division in mouse Lewis lung carcinoma cells.
Characterization of 3D embryonic C57BL/6 and A/J mouse midbrain micromass in vitro culture systems for developmental neurotoxicity testing.
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
miR34a/GOLPH3 Axis abrogates Urothelial Bladder Cancer Chemoresistance via Reduced Cancer Stemness.
Soluble expression of recomb inant cMyc, Klf4, Oct4, and Sox2 proteins in bacteria and transduction into living cells.
Bufalin reverses acquired drug resistance by inhibiting stemness in colorectal cancer cells.
Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice.
Silencing of Btbd7 Inhibited Epithelial-Mesenchymal Transition and Chemoresistance in CD133(+) Lung Carcinoma A549 Cells.
Overexpression of PER3 Inhibits Self-Renewal Capability and Chemoresistance of Colorectal Cancer Stem-Like Cells via Inhibition of Notch and β-Catenin Signaling.
Generation and characterization of induced pluripotent stem cells from guinea pig fetal fibroblasts.
The X-Linked Intellectual Disability Protein IL1RAPL1 Regulates Dendrite Complexity.
Transcriptional suppression of microRNA-27a contributes to laryngeal cancer differentiation via GSK-3β-involved Wnt/β-catenin pathway.
Injury Induces Endogenous Reprogramming and Dedifferentiation of Neuronal Progenitors to Multipotency.
Expression of Stem Cell Markers and Dopamine D2 Receptors in Human and Rat Prolactinomas.
Sox2 and Pax6 Play Counteracting Roles in Regulating Neurogenesis within the Murine Olfactory Epithelium.
miR-612 suppresses stem cell-like property of hepatocellular carcinoma cells by modulating Sp1/Nanog signaling.
Differential epigenetic effects of chlorpyrifos and arsenic in proliferating and differentiating human neural progenitor cells.
Persistent Cytomegalovirus Infection in Amniotic Membranes of the Human Placenta.
Combinatorial enzymatic digestion with thermolysin and collagenase type I improved the isolation and culture effects of hair cell progenitors from rat cochleae.
ROCK inhibitor Y27632 promotes proliferation and diminishes apoptosis of marmoset induced pluripotent stem cells by suppressing expression and activity of caspase 3.
Hyperglycemic Stress Impairs the Stemness Capacity of Kidney Stem Cells in Rats.
The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signaling.
Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells.
Low concentration of serum helps to maintain the characteristics of NSCs/NPCs on alkali-treated PHBHHx film in vitro.
Correlation of ALDH1, CD44, OCT4 and SOX2 in tongue squamous cell carcinoma and their association with disease progression and prognosis.
Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle.
In vitro neurogenesis from neural progenitor cells isolated from the hippocampus region of the brain of adult rats exposed to ethanol during early development through their alcohol-drinking mothers.
Cao Z, Pan C, Liu Z, Quan Q, Li M, Huang Y, Liang C, Chen Y, Fan T, Chen P, Kai F, Zhu S, Li S, Su X, Wang F, Fu L, Zhang B
International journal of biological sciences 2026;22(2):970-994
International journal of biological sciences 2026;22(2):970-994
SHP2 improved Late-onset fetal growth restriction via modulating ROS/BRD4/PI3K/YAP/PIGF signaling induced angiogenesis.
Li F, Li Y, Hao W, Zhang X, Shen X, Yang B, Zhang W, Fu L, Gu S
PloS one 2026;21(2):e0342649
PloS one 2026;21(2):e0342649
Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation.
Li C, Yang L, Zhang Y, Zhao B, Qu H
Oncology reports 2026 May;55(5)
Oncology reports 2026 May;55(5)
Brain-Targeted RVG-Liposomal Melatonin Ameliorates Manganese Neurotoxicity by Enhancing Neurogenesis and Modulating Systemic Amino Acid Profiles.
Wang X, Chen J, Xia J, Ma T, Yang W, Shan T, He W, Zhang G, Xia Z, Wang W, Liu Z, Zheng Y, Nong K, Niu P, Chen T
Journal of pineal research 2026 Mar;78(2):e70137
Journal of pineal research 2026 Mar;78(2):e70137
Schisantherin A promotes neural differentiation of stem cells from apical papilla to improve mandibular development via mental nerve repair.
Du L, Li A, Tang Z, Yang H, Shi X, Wang S, Qiu Z, Yang X, Huang Y
Stem cell research & therapy 2026 Mar 6;17(1)
Stem cell research & therapy 2026 Mar 6;17(1)
Weiyan Tongluo Granules attenuate gastric intestinal metaplasia through PPARγ/NF-κB/CDX2 signaling pathway.
Liang Y, Su S, Jin T, Mou J, Wu H, Yan N, Li X, Yao S, Wen Y, Liu F, Li P
Chinese medicine 2026 Mar 4;21(1)
Chinese medicine 2026 Mar 4;21(1)
H3K9me2 is a determinant for the mitosis-to-meiosis transition in female germ cells.
Hu Y, Zhou H, Shi L, Liu K, Meng X, Guo X, Shan L, Hu F, Liu Y, Zhang T, Zhou Y
Cell death & disease 2026 Mar 2;17(1)
Cell death & disease 2026 Mar 2;17(1)
Pseudoginsenoside F11 enhances YBX1-mediated transcriptional repression of PRPS2 to inhibit the stemness and pulmonary metastasis of triple- negative breast cancer.
Xu K, Bai Y, Chen H, Liu Y, Liu H, Liu Y, Wan X, Liu Y, Chen Y, Shi Y, Xiang R, Zeng B, Cui Y, Fan Y, Li J, Wang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158064
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158064
Functional and metabolic dysbiosis of the gut microbiome in the tumoral immune microenvironment of hepatocellular carcinoma.
He Q, Wu H, Guo M, Ye R, Li H, Zhang Q
Cellular signalling 2026 Jul;143:112455
Cellular signalling 2026 Jul;143:112455
Adipose-derived stem cells (ADSCs)-derived DKK1 promotes cutaneous wound healing by inducing M2 macrophage polarization via PI3K/AKT and JNK activation.
Liu D, Liu N, Liu X, Liu Y, Zhang H, Zhou Z, Zheng J, Tian Y
Biochimica et biophysica acta. Molecular cell research 2026 Jan;1873(1):120077
Biochimica et biophysica acta. Molecular cell research 2026 Jan;1873(1):120077
CNOT3 resists ovarian aging by accelerating oocyte maturation and promoting ESCs differentiation.
Li N, Huang E, Wang R, Li J, Yuan X
Stem cell research & therapy 2026 Jan 17;17(1):83
Stem cell research & therapy 2026 Jan 17;17(1):83
Precise excision of expanded GGC repeats in NOTCH2NLC via CRISPR/Cas9 for treating neuronal intranuclear inclusion disease.
Xie N, Pan Y, Tong H, Lin Y, Jiang Y, Wang Z, Wan J, Zhang W, Wang X, Sun X, Yan S, Yin P, Sun Q, Qi C, Tian Y, Shen L, Jiang H, Liang D, Tang B, Li S, Li XJ, Liu Q
Nature communications 2026 Jan 13;17(1):1683
Nature communications 2026 Jan 13;17(1):1683
Wnt/β-Catenin Activation by iCRT3 Enhanced the Pluripotency of Bovine Expanded Pluripotent Stem Cells.
Liu D, Qu B, Wang J, Han X, Su M, Li X, Li Y, Li X
Animals : an open access journal from MDPI 2026 Feb 9;16(4)
Animals : an open access journal from MDPI 2026 Feb 9;16(4)
HSPA5 promotes YAP/TAZ stability independently of the Hippo pathway and induces proneural-to-mesenchymal transition in glioblastoma.
Gui S, Yu W, Song Z, Peng L, Luo H, Huang K, Xiao J, Xie J, Cai S, Yuan S, Tao Z, Cheng Z
Cell death & disease 2026 Feb 7;17(1):208
Cell death & disease 2026 Feb 7;17(1):208
Integrated single-cell and spatial transcriptomic profiling decodes lineage plasticity and immune microenvironment remodeling in prostate cancer progression.
Yu H, Wang Y, He M, Chen Y, Bi J, Lin X, Cui X
Molecular cancer 2026 Feb 28;25(1)
Molecular cancer 2026 Feb 28;25(1)
Taurine attenuates arsenic-induced neurotoxicity through modulation of gut microbiota structure.
Zhang H, Qiao W, Tai D, Lv Y, Qi H
Psychopharmacology 2026 Feb 19;
Psychopharmacology 2026 Feb 19;
The GOLM1-ACLY pathway regulates macrophage-secreted EFEMP1 via H3K27ac modifications to drive tumor progression.
Zhen L, Min M, Mo X, Zhao G, Li H, Liu M, Wan L, Yang X, Huang L, Zhang Y, Gao Q, Zhong H, Qiang G, Wu F, Xie Q, Wei C, Zhao R
Journal of advanced research 2026 Apr;82:765-783
Journal of advanced research 2026 Apr;82:765-783
Recombinant Filaggrin-2 microneedles reverse androgenetic alopecia by rescuing mitochondrial dysfunction in dermal papilla cells.
Chang R, Hao J, Huang Z, Zhang X, Li Z, Wu Q, Tang X, Li Y, Xia H, Deng J, Yang Y, Huang Y
International journal of biological macromolecules 2026 Apr;357:151522
International journal of biological macromolecules 2026 Apr;357:151522
Microalgae-MOF integrated drug delivery system for cranial radiotherapy and chemotherapy-induced brain injury.
Li X, Ye J, Zhong D, Xie J, Ding Z, Zhou M
Biomaterials 2026 Apr;327:123767
Biomaterials 2026 Apr;327:123767
HSP90AB1-Mediated Ubiquitin-Proteasome Degradation of ITGBL1 Promotes Osteosarcoma Progression by Inhibiting Endoplasmic Reticulum Stress-Induced Autophagy.
Wang Z, Guo Z, Cao C, Wang Z, Huang Z, Zhang X, Zheng Y, She D, Zhu H, Yu L, Zhao X, Xiang D, Liao S, He X, Ji X, Wu C, Xu CX, Xu M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e15651
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e15651
OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17-Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC.
Cui L, Si S, Ye M, Lin P, Zou M, Lin Y, Chen X, Guo B, Sun W, Zhao X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e15452
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e15452
Discovery, Optimization, and Biological Evaluation of 2-Cyano-2-(9H-xanthen-9-ylidene)acetamide Derivatives as ZNF207 Inhibitors for Anti-Glioma Therapy.
Gao M, Wang J, Wang Y, Li J, Feng J, Gu C, Wang Z, Gong X, Zhou W, Chen S, Xia X, Tang X, Yang Y, Zhang D, Ding Y, Zhang M
Journal of medicinal chemistry 2026 Apr 9;69(7):7594-7641
Journal of medicinal chemistry 2026 Apr 9;69(7):7594-7641
Nuclear N-glycosylation maintains H3K9me3 heterochromatin and genomic stability.
Tang X, Dai R, Qing L, Zhang Z, Li H, Lu L, Lin H, Ji D, Dan W, He Y, Liu X, Yang T, Chang W, Mao Y, Sun S, Ding J
Nature cell biology 2026 Apr 28;
Nature cell biology 2026 Apr 28;
KRT15 identified by scRNA-Seq and machine learning as stemness regulator and prognostic biomarker in ESCC.
Xiong K, Zhu Y, Fang H, Sun X, Li Z, Tuerxun D, Zhang P
iScience 2026 Apr 17;29(4):115020
iScience 2026 Apr 17;29(4):115020
Generating Microglia-Integrated Cortical Organoids from Human Embryonic Stem Cells.
Quan H, Liu X, Yan M, Ai Z, Niu B, Jiang J, Chang H, Fu W, Zhang R
Stem cell reviews and reports 2026 Apr 16;
Stem cell reviews and reports 2026 Apr 16;
Hyperthermia Inhibits Growth and Stemness of Esophageal Squamous Cell Carcinoma Cells Through Promoting Degradation of GLI1.
Qin H, Li X, Duan S, Li S, Ren M
Stem cells international 2025;2025:7249890
Stem cells international 2025;2025:7249890
Comprehensive Bioinformatics Analysis and Validation of the Mechanism of Glutamic-pyruvic Transaminase 2 in Bladder Cancer.
Dong H, Li H, Chen S, Wang Q, Zhang Y, Shi H, Zuo J, Chen J, Wang J, Wang H
Journal of Cancer 2025;16(15):4357-4370
Journal of Cancer 2025;16(15):4357-4370
Comprehensive analysis of IGFL1 in colorectal cancer and its promotion of tumour progression via inhibition of lipophagy.
Wang A, Zhou Y, Deng Z, Duan Y, Dai Z, Jiang D
Frontiers in immunology 2025;16:1719525
Frontiers in immunology 2025;16:1719525
A novel pathway for stemness propagation and chemoresistance in non-small cell lung cancer via phosphorylated PKM2-loaded small extracellular vesicles.
Wang J, Liu L, Gao X, Liu X, Dai Y, Mao Z, Huang S, Li J, Wang D, Qi Y, Han Y, Xu Y, Chua CYX, Grattoni A, Xie W, Yang H, Huang G
Theranostics 2025;15(8):3439-3461
Theranostics 2025;15(8):3439-3461
Establishment of an induced pluripotent stem cell (iPSC) line (INNDSUi011-A) from a patient with autosomal dominant spastic paraplegia 9A due to ALDH18A1 mutation.
Shan D, Wang H, Li J, Wang Y, Liu F
Stem cell research 2025 Sep;87:103807
Stem cell research 2025 Sep;87:103807
Daughter Cells Budding From PGCCs and Their Clinicopathological Significances in Oral Squamous Cell Carcinoma.
Zhuo S, Jing C, Liu X, Yue J, Zhang W, Zhang S
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2025 Sep;54(8):687-693
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2025 Sep;54(8):687-693
Genipin stabilized fibrin microbeads: Carrying cytokines to form niches for stem cell differentiation.
Chen Q, Hu P, Yang W, Xu X, Shao G
Journal of biomaterials applications 2025 Sep;40(3):345-358
Journal of biomaterials applications 2025 Sep;40(3):345-358
Myogenic induced adipose-derived stem cells sheets combined with electrospun scaffolds of silk fibroin and poly(lactide-co-glycolide) for stress urinary incontinence treatment.
Liu M, Li Y, Zhao Y, Sun F, Lu Y, Wu J, Zou Q
Journal of molecular histology 2025 Sep 10;56(5):306
Journal of molecular histology 2025 Sep 10;56(5):306
Transplanting neural stem cells overexpressing miRNA-21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28-let-7 signaling pathway.
Dai W, Li Y, Du J, Shen G, Fan M, Su Z, Xu F, Yuan F
Animal models and experimental medicine 2025 Oct;8(10):1760-1774
Animal models and experimental medicine 2025 Oct;8(10):1760-1774
CROT overactivation within peroxisomes confers chemoresistance to non-small cell lung cancer by targeting fatty acid oxidation-Nrf2-ferroptosis resistance axis.
Hua C, Zhang G, Yu W, Zhou J, Ru L, Xue G, Zheng L, Wang M, Wang Y, Yu D, Wang Q, Liu J, Wang R, Deng W, Tang R, Guo W
Pharmacological research 2025 Oct;220:107911
Pharmacological research 2025 Oct;220:107911
Breaking the link between morphology and potency for mESCs.
Fan Y, Wang X, Zhai Z, Huang T, Li W, Liang Z, Ma Z, Fu Y, Li P, Kuang J, Pei D
Cell & bioscience 2025 Oct 23;15(1):146
Cell & bioscience 2025 Oct 23;15(1):146
PNO1 served as a potential biomarker to promote the stemness and progression of breast cancer via the NF-κB signaling pathway.
Wang X, Yue P, Liu D, Wen X, Zhang X, Sun B, Luo Y, Chen L, Li W, Liu H, He Y, Tong Z, Guo H
Stem cells (Dayton, Ohio) 2025 Oct 16;43(11)
Stem cells (Dayton, Ohio) 2025 Oct 16;43(11)
Histone Lactylation-Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells.
Li J, Tang C, Zhang X, Xing R, Guo Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e03897
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e03897
Investigating the impact of MCTP2 on immune suppression and drug resistance in glioblastoma.
Chen Y, Yan X, Huang Q, Pang H, Li C, Su X, Ye Y, Wang Z, Chen Y, Zhou Y
Functional & integrative genomics 2025 Nov 26;25(1):255
Functional & integrative genomics 2025 Nov 26;25(1):255
Ethylene Glycol and Trehalose Cryopreservation of Cell-Laden Hydrogel Microspheres Enabled by Microfluidic Fabrication.
Yu J, Pan P, Li X, Zhang J, Dingzhang X, Jiang X, Wang X, Berdiyar J, Wang Q, Xu X, Cao X
Biomacromolecules 2025 Nov 10;26(11):7289-7299
Biomacromolecules 2025 Nov 10;26(11):7289-7299
Ginsenoside Rh2 as a novel PIN1 inhibitor disrupting the cancer stem cell-like phenotype in non-small cell lung cancer.
Liu X, Mao Z, Yang J, Zhu Q, Dong X, Huang G, Shen X, Zhang L, Yang H
Journal of translational medicine 2025 Nov 10;23(1):1256
Journal of translational medicine 2025 Nov 10;23(1):1256
A new protocol for the development of organoids based on molecular mechanisms in the developing newborn rat brain: Prospective applications in the study of Alzheimer's disease.
Tzekaki E, Bekiari C, Pantazaki A, Tsantarliotou M, Tsolaki M, Lavrentiadou SN
Journal of neuroscience methods 2025 May;417:110404
Journal of neuroscience methods 2025 May;417:110404
Neuroprotective Effects of Qi Jing Wan and Its Active Ingredient Diosgenin Against Cognitive Impairment in Plateau Hypoxia.
Xia T, Yan Z, Shen P, Chang M, Zhang N, Zhang Y, Chen Q, Wang R, Tong L, Zhou W, Ni Z, Gao Y
Pharmaceuticals (Basel, Switzerland) 2025 May 17;18(5)
Pharmaceuticals (Basel, Switzerland) 2025 May 17;18(5)
NSUN4 Facilitates the Activity of Oncogenic Protein CDC20 to Promote NSCLC Development by Mediating m5C Modification of CDC20 mRNA.
Li Z, Wu X
Thoracic cancer 2025 Mar;16(5):e70023
Thoracic cancer 2025 Mar;16(5):e70023
GNE-317 Reverses MSN-Mediated Proneural-to-Mesenchymal Transition and Suppresses Chemoradiotherapy Resistance in Glioblastoma via PI3K/mTOR.
Yang YC, Jin XY, Yang LL, Xu X, Xie Y, Ai YD, Li XC, Ma YC, Xu CL, Li Q, Ge XL, Yi TL, Jiang T, Wang XG, Piao YZ, Jin X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2412517
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2412517
RNA-binding protein SAMD4A targets FGF2 to regulate cardiomyocyte lineage specification from human embryonic stem cells.
Yi N, Wang HR, Zhu YP, Xiao T, Lin Q, Liu H, Meng YL, Sun YZ, Lin F, Hu SY, Cao HM, Zhang JF, Peng LY, Li L
Stem cell research & therapy 2025 Mar 18;16(1):144
Stem cell research & therapy 2025 Mar 18;16(1):144
Identification of a non-inhibitory aptameric ligand to CRL2(ZYG11B) E3 ligase for targeted protein degradation.
Yang Z, Chen M, Ge R, Zhou P, Pan W, Song J, Ma S, Chen S, Xu C, Zhou M, Mi W, Ni H, Chen H, Yao X, Dong X, Chen Y, Zhou J, Xuan C, Dong C, Yan H, Xie S
Nature communications 2025 Mar 13;16(1):2494
Nature communications 2025 Mar 13;16(1):2494
The asymmetric expression of HSPA2 in blastomeres governs the first embryonic cell-fate decision.
Gao J, Wang J, Liu S, Song J, Zhang C, Liu B, Wu K
eLife 2025 Mar 10;13
eLife 2025 Mar 10;13
Generation of an induced pluripotent stem cell (iPSC) line (INNDSUi009-A) from a patient with amyotrophic lateral sclerosis due to SOD1 mutation.
Li B, Mu H, Shan D, Yang Y, Wang Y, Li J, Wang H, Sun X, Ji X, Zhan Z, Jiao Y, Tang Y, Kong B, Gao B, Wang Y, Sun P, Liu F
Stem cell research 2025 Jun;85:103704
Stem cell research 2025 Jun;85:103704
Conjugated therapy with coaxially printed neural stem cell-laden microfibers and umbilical cord mesenchymal stem cell derived exosomes on complete transactional spinal cord defects.
Li X, Zhang J, Zhang Y, Guo L, Gao M, Wang Y, Qiu W, Yuan Y, Zhu J, Liu B, Xiong H, Xu T, Xu R
Materials today. Bio 2025 Jun;32:101639
Materials today. Bio 2025 Jun;32:101639
Vegfr3 activation of Pkd2l1(+) CSF-cNs triggers the neural stem cell response in spinal cord injury.
Cao L, Shangguan Z, Zhang Y, Luo Z, Chen C, Yan H, Fu X, Tan W, Wang C, Dou X, Zheng C, Li Q
Cellular signalling 2025 Jun;130:111675
Cellular signalling 2025 Jun;130:111675
Analysis of astrocyte progenitors derived from human induced pluripotent stem cells in vitro and following transplantation into the intact spinal cord.
Niceforo A, Jin Y, Ramakrishnan S, Lindner-Jackson M, Qiang LO, Fischer I
bioRxiv : the preprint server for biology 2025 Jun 28;
bioRxiv : the preprint server for biology 2025 Jun 28;
Identification of the Oncogenic Role of MSH2 in the Stemness and Progression of Glioma Through Regulating Wnt Signaling Pathway.
Liu J, Chen J, Jiang L
Cancer medicine 2025 Jul;14(13):e70993
Cancer medicine 2025 Jul;14(13):e70993
Melatonin as an Alleviator in Decabromodiphenyl Ether-Induced Aberrant Hippocampal Neurogenesis and Synaptogenesis: The Role of Wnt7a.
Shen J, Gao L, Gao J, Wang L, Yan D, Wang Y, Meng J, Li H, Chen D, Wu J
Biomolecules 2025 Jul 27;15(8)
Biomolecules 2025 Jul 27;15(8)
NKD1 enhances colon cancer progression by inhibiting the autophagic degradation of MYC.
Lu W, Tang J, Wang Y, Gu X, Zhang H, Liu Y, Xiao Y, Zhu Q, Deng J, Shen Y, Jiang A, Xu Y, Jin J, Hou Y, Liu Q
Cell death & disease 2025 Jul 17;16(1):532
Cell death & disease 2025 Jul 17;16(1):532
Wnt5a promotes VM formation by modulating the stemness and EMT progression of prostate cancer cell.
Liu B, Li X, Wang S, Jia H, Zhang X, Dong Q, Li J
Translational oncology 2025 Jan;51:102155
Translational oncology 2025 Jan;51:102155
Tetramethylpyrazine attenuates the cancer stem cell like-properties and doxorubicin resistance by targeting HMGCR in breast cancer.
Jiang X, Wang M, Cui G, Wu Y, Wei Z, Yu S, Wang A, Zou W, Pan Y, Li X, Lu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156344
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156344
Supervillin-Mediated ZO-1 Downregulation Facilitates Migration of Cisplatin-Resistant HCT116 Colorectal Cancer Cells.
Hong Y, Li X, Mao R, Zhou F, Li S, Zhu C, Jin L
Journal of cellular biochemistry 2025 Jan;126(1):e30699
Journal of cellular biochemistry 2025 Jan;126(1):e30699
TC2N maintains stem cell-like characteristics to accelerate lung carcinogenesis by blockade of dual specificity protein phosphatase 3.
Gu J, Lv YF, Xia JY, Bai FH, Gong J, Pan GQ, Liu B, Huang L, Guo QN, Hao XL
Cell & bioscience 2025 Jan 23;15(1):8
Cell & bioscience 2025 Jan 23;15(1):8
Nitric Oxide-Releasing Mesoporous Hollow Cerium Oxide Nanozyme-Based Hydrogel Synergizes with Neural Stem Cell for Spinal Cord Injury Repair.
Liu D, Niu R, Wang S, Shao L, Yang X, Liu X, Ma X, Zhu Z, Zhang J, Shi B, Ni H, Du X
ACS nano 2025 Jan 21;19(2):2591-2614
ACS nano 2025 Jan 21;19(2):2591-2614
Dual-phase nanoscissors disrupt vasculature-breast cancer stem cell crosstalk for breast cancer treatment.
Qi Y, Lv S, Xie C, Du S, Yao J
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:781-793
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:781-793
Generation of an induced pluripotent stem cell (iPSC) line (INNDSUi007-A) from a patient with Kennedy disease.
Li B, Yang Y, Wang Y, Shan D, Li J, Wang H, Sun X, Tang Y, Jiao Y, Ji X, Zhan Z, Kong B, Gao B, Wang Y, Sun P, Liu F
Stem cell research 2025 Feb;82:103638
Stem cell research 2025 Feb;82:103638
Long non-coding RNA MIR4435-2HG modulates pancreatic cancer stem cells and chemosensitivity to gemcitabine by targeting the miR-1252-5p/STAT1.
Xie B, Wu P, Liu H, Yang X, Huang L
Journal of translational medicine 2025 Feb 7;23(1):165
Journal of translational medicine 2025 Feb 7;23(1):165
Mesenchymal stem cells overexpressing neuropeptide S promote the recovery of rats with spinal cord injury by activating the PI3K/AKT/GSK3β signaling pathway.
Yang W, Li Y, Tang Y, Tao Z, Yu M, Sun C, Ye Y, Xu B, Zhao X, Zhang Y, Lu X
Stem cell research & therapy 2025 Feb 28;16(1):100
Stem cell research & therapy 2025 Feb 28;16(1):100
Enhanced or reversible RNA N6-methyladenosine editing by red/far-red light induction.
Tang H, Han S, Jie Y, Jiang X, Zhang Y, Peng J, Wang F, Li X, Zhou X, Jiang W, Weng X
Nucleic acids research 2025 Feb 27;53(5)
Nucleic acids research 2025 Feb 27;53(5)
Effects of mesenchymal stem cells from different sources on the biological functions of multiple myeloma cells.
Li Y, Liu Y, Yang X, Yang B, Cheng J, Chen J, Yuan X, Xu X, Liu G, He Z, Wang F
Stem cell research & therapy 2025 Feb 25;16(1):89
Stem cell research & therapy 2025 Feb 25;16(1):89
Low-intensity pulsed ultrasound promotes proliferation and differentiation of neural stem cells to enhance spinal cord injury recovery.
Liao YH, Tian MH, Zhou WY, He BQ, Tang C, Tang Q, Ye RP, Zhong DJ
Molecular biology reports 2025 Feb 18;52(1):245
Molecular biology reports 2025 Feb 18;52(1):245
Rack1 promotes breast cancer stemness properties and tumorigenesis through the E2F1-SOX2 axis.
Jia Y, Zhang L, Zhou W, Chen S, Zhang H, Liu L, Guo H, Wang Z, Cui Y, Niu R, Zhang F
Cancer cell international 2025 Feb 12;25(1):40
Cancer cell international 2025 Feb 12;25(1):40
The PLEKHA1-TACC2 fusion gene drives tumorigenesis via vascular mimicry formation in esophageal squamous-cell carcinoma.
Yang T, Lin ZR, Xia TL, Liu SX, Yuan BY, Luo YL, Du WT, Lei CB, Nie YZ, Zeng MS, Zhong Q
Cell death and differentiation 2025 Dec;32(12):2323-2339
Cell death and differentiation 2025 Dec;32(12):2323-2339
Lactate mitochondrial oxidation drives stemness potential in metastatic breast cancer.
Zhang JJ, Tian RF, Song CG, Liu R, He D, Zhang GQ, Fan XY, Duan ZC, Zhang K, Zhang TJ, Chen YT, Zhang J, Wang K, Zhao JM, Yang XM, Chen ZN, Li L
Nature communications 2025 Dec 18;17(1):399
Nature communications 2025 Dec 18;17(1):399
Machine learning-based identification of kbhb-affected tumor cell subsets as prognostic and therapeutic targets in breast cancer.
Yuan Q, Sha Y, Ye R, Yu H, Ni L, Han J, Deng L
Journal of translational medicine 2025 Dec 11;24(1):71
Journal of translational medicine 2025 Dec 11;24(1):71
Valproic acid boosts hair follicle stem cell resilience to oxygen-glucose deprivation through autophagy induction and AKT/mTOR suppression.
Keshavarzi F, Salehi MS, Pandamooz S, Dastghaib S, Siri M, Dianatpour M, Borhani-Haghighi A, Mostafavi-Pour Z, Mokarram P
Scientific reports 2025 Dec 10;16(1):2253
Scientific reports 2025 Dec 10;16(1):2253
SETD5 facilitates stemness and represses ferroptosis via m6A-mediating PKM2 stabilization in non-small cell lung cancer.
Liu X, Cui Y, Gong J, Yu X, Cui Y, Xuan Y
Oncogene 2025 Aug;44(29):2474-2489
Oncogene 2025 Aug;44(29):2474-2489
The combination of FLI, ITS, pFF, and citrate improves the developmental potential of gilt oocytes during in vitro maturation.
Chen Z, Zhang C, Yan C, Peng C, Xie H, Pan Y, Qi L, Qu C, Zhao Y, Tang Z
Animal reproduction science 2025 Aug;279:107945
Animal reproduction science 2025 Aug;279:107945
Hydroxysafflor yellow A promotes the proliferation and differentiation of endogenous neural stem cells with neural regenerative effects in ischemic stroke.
Wang Z, Liu Z, Hao Y, Zhu Z, Hong J, Cui L, Cheng G, Tan R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Aug;144:156905
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Aug;144:156905
NR2F2 and its contribution to lymph node metastasis in oral squamous cell carcinoma.
Liu XH, Zhong NN, Yi JR, Wang GR, Xiao Y, Zhu ZR, Man QW, Li Z, Liu B, Bu LL
Cellular signalling 2025 Aug;132:111814
Cellular signalling 2025 Aug;132:111814
Mesenchymal stem cell-derived lncRNAs NKILA contributes to stemness and chemoresistance by fatty acid oxidation in gastric cancer via miR-485-5p/STAT3.
Lyu XJ, Zhou L, Jiang XM, Zheng D
World journal of gastrointestinal oncology 2025 Aug 15;17(8):105006
World journal of gastrointestinal oncology 2025 Aug 15;17(8):105006
Generation of an induced pluripotent stem cell (iPSC) line (INNDSUi008-A) from a patient with Spinocerebellar Ataxia Type 3.
Li B, Wang Y, Yang Y, Shan D, Li J, Wang H, Sun X, Zhan Z, Ji X, Tang Y, Jiao Y, Kong B, Gao B, Sun P, Liu F, Wang Y
Stem cell research 2025 Apr;84:103675
Stem cell research 2025 Apr;84:103675
N4-Acetylcytidine-Mediated CD2BP2-DT Drives YBX1 Phase Separation to Stabilize CDK1 and Promote Breast Cancer Progression.
Wang H, Zhao B, Zhang J, Hu Q, Zhou L, Zhang Y, Cai Y, Qu Y, Jiang T, Zhang D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2411834
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2411834
Lipopolysaccharide Induces Resistance to CAR-T Cell Therapy of Colorectal Cancer Cells through TGF-β-Mediated Stemness Enhancement.
Tao M, Xue M, Zhou D, Zhang L, Hou X, Zhu X, Feng S, Yan H, Qian X, Wei L, Zong C, Yang X, Zhang L
Molecular pharmaceutics 2025 Apr 7;22(4):1790-1803
Molecular pharmaceutics 2025 Apr 7;22(4):1790-1803
Ara-C suppresses H3 K27-altered spinal cord diffuse midline glioma growth and enhances immune checkpoint blockade sensitivity.
Pang B, Wu Y, An S, Chang Y, Yan H, Lin H, Zhao Z, Wu F, Chang Q, Jia W, Jiang T, Wang Y, Chai R
Science advances 2025 Apr 18;11(16):eadu3956
Science advances 2025 Apr 18;11(16):eadu3956
3D mesenchymal stem cell exosome-functionalized hydrogels for corneal wound healing.
Xu Y, Wei C, Ma L, Zhao L, Li D, Lin Y, Zhou Q, Xie L, Wang F
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:630-646
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:630-646
A Hybrid Manganese Nanoparticle Simultaneously Eliminates Cancer Stem Cells and Activates STING Pathway to Potentiate Cancer Immunotherapy.
Wu Y, Diao P, Peng Y, Yang Y, Wang Y, Lv P, Li J, Wang D, Cai T, Cheng J
ACS nano 2025 Apr 1;19(12):12237-12252
ACS nano 2025 Apr 1;19(12):12237-12252
ΔNp63α promotes cigarette smoke-induced renal cancer stem cell activity via the Sonic Hedgehog pathway.
Zhao Y, Ma N, Wu W, Wu Y, Zhang W, Qian W, Sun X, Zhang T
Genetics and molecular biology 2024;47(2):e20230347
Genetics and molecular biology 2024;47(2):e20230347
VEGFA/NRP-1/GAPVD1 axis promotes progression and cancer stemness of triple-negative breast cancer by enhancing tumor cell-macrophage crosstalk.
Wang L, Zhang L, Zhao L, Shao S, Ning Q, Jing X, Zhang Y, Zhao F, Liu X, Gu S, Zhao X, Luo M
International journal of biological sciences 2024;20(2):446-463
International journal of biological sciences 2024;20(2):446-463
KYNU Expression Promotes Cisplatin Resistance in Esophageal Cancer.
Lu Y, Zhao X, Yuan M, Zhao M, Liu K, Zhang M, Qiu X, Yu X, Liu X, Wei D, Xie J, Cheng Z
Journal of Cancer 2024;15(9):2475-2485
Journal of Cancer 2024;15(9):2475-2485
Identification of hub genes within the CCL18 signaling pathway in hepatocellular carcinoma through bioinformatics analysis.
Mao J, Tao Y, Wang K, Sun H, Zhang M, Jin L, Pan Y
Frontiers in oncology 2024;14:1371990
Frontiers in oncology 2024;14:1371990
Strategic targeting of miR-183 and β-catenin to enhance BMSC stemness in age-related osteoporosis therapy.
Jiang N, Jiang J, Wang Q, Hao J, Yang R, Tian X, Wang H
Scientific reports 2024 Sep 14;14(1):21489
Scientific reports 2024 Sep 14;14(1):21489
Integrated machine learning algorithms identify KIF15 as a potential prognostic biomarker and correlated with stemness in triple-negative breast cancer.
Guo Q, Qiu P, Pan K, Liang H, Liu Z, Lin J
Scientific reports 2024 Sep 13;14(1):21449
Scientific reports 2024 Sep 13;14(1):21449
USP14 promotes the cancer stem-like cell properties of OSCC via promoting SOX2 deubiquitination.
Liu C, Zhou S, Tang W
Oral diseases 2024 Oct;30(7):4255-4265
Oral diseases 2024 Oct;30(7):4255-4265
METTL3 inhibitor suppresses the progression of prostate cancer via IGFBP3/AKT pathway and synergizes with PARP inhibitor.
Chen X, Wang M, Wang H, Yang J, Li X, Zhang R, Ding X, Hou H, Zhou J, Wu M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117366
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117366
The effects of BMP2 and the mechanisms involved in the invasion and angiogenesis of IDH1 mutant glioma cells.
Xu H, Cao Y, Ruan J, Wang F, He Y, Yang L, Yu T, Du F, Zhang N, Cao X
Journal of neuro-oncology 2024 Oct;170(1):161-171
Journal of neuro-oncology 2024 Oct;170(1):161-171
Chronic lung inflammation and CK14+ basal cell proliferation induce persistent alveolar-bronchiolization in SARS-CoV-2-infected hamsters.
Li C, Xiao N, Song W, Lam AH, Liu F, Cui X, Ye Z, Chen Y, Ren P, Cai J, Lee AC, Chen H, Ou Z, Chan JF, Yuen KY, Chu H, Zhang AJ
EBioMedicine 2024 Oct;108:105363
EBioMedicine 2024 Oct;108:105363
Construction of a lung cancer 3D culture model based on alginate/gelatin micro-beads for drug evaluation.
Zhao Z, Feng X, Wu H, Chen S, Ma C, Guan Z, Lei L, Tang K, Chen X, Dong Y, Tang Y
Translational lung cancer research 2024 Oct 31;13(10):2698-2712
Translational lung cancer research 2024 Oct 31;13(10):2698-2712
TRIB3 inhibition by palbociclib sensitizes prostate cancer to ferroptosis via downregulating SOX2/SLC7A11 expression.
Zhang Y, Liu C, Yang Y, Ren H, Ren T, Huang Y, Zhang S, Sun Q, Huang H
Cell death discovery 2024 Oct 3;10(1):425
Cell death discovery 2024 Oct 3;10(1):425
The role and mechanism of NRG1/ErbB4 in inducing the differentiation of induced pluripotent stem cells into cardiomyocytes.
Li X, Zhang H, Li W, Tuo H, He B, Jiang H
BMC cardiovascular disorders 2024 Oct 16;24(1):559
BMC cardiovascular disorders 2024 Oct 16;24(1):559
Combining single-cell profiling and functional analysis explores the role of pseudogenes in human early embryonic development.
Sun M, Chang L, He L, Wang L, Jiang Z, Si Y, Yu J, Ma Y
Journal of genetics and genomics = Yi chuan xue bao 2024 Nov;51(11):1173-1186
Journal of genetics and genomics = Yi chuan xue bao 2024 Nov;51(11):1173-1186
Anti-Stress and Anti-ROS Effects of MnOx-Functionalized Thermosensitive Nanohydrogel Protect BMSCs for Intervertebral Disc Degeneration Repair.
Wang X, Yu L, Duan J, Chang M, Hao M, Xiang Z, Qiu C, Sun J, Di D, Xia H, Li D, Yuan S, Tian Y, Qiu J, Liu H, Liu X, Sang Y, Wang L
Advanced healthcare materials 2024 Nov;13(29):e2400343
Advanced healthcare materials 2024 Nov;13(29):e2400343
iPSC-derived NK cells with site-specific integration of CAR19 and IL24 at the multi-copy rDNA locus enhanced antitumor activity and proliferation.
Zhang Y, Shi Q, Wang P, Huang C, Tang S, Zhou M, Hu Q, Wu L, Liang D
MedComm 2024 May;5(5):e553
MedComm 2024 May;5(5):e553
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Wu Z, Zhou Y, Hou X, Liu W, Yin W, Wang L, Cao Y, Jiang Z, Guo Y, Chen Q, Xie W, Wang Z, Shi N, Liu Y, Gao X, Luo L, Dai J, Ren C, Jiang X
Bioactive materials 2024 May;35:242-258
Bioactive materials 2024 May;35:242-258
Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages.
Dong M, Zhang X, Peng P, Chen Z, Zhang Y, Wan L, Xiang W, Liu G, Guo Y, Xiao Q, Wang B, Guo D, Zhu M, Yu X, Wan F
Cancer letters 2024 May 28;590:216801
Cancer letters 2024 May 28;590:216801
α5-nAChR/ADAM10 signaling mediates nicotine-related cutaneous melanoma progression via STAT3 activation.
Li X, Meng X, Fan H, Wang Y, Jia Y, Jiao J, Ma X
Archives of dermatological research 2024 May 25;316(6):269
Archives of dermatological research 2024 May 25;316(6):269
GFP-labeled Schwann cell-like cells derived from hair follicle epidermal neural crest stem cells promote the acellular nerve allografts to repair facial nerve defects in rats.
Zhang J, Zhu G, Tang L, Li X
Experimental cell research 2024 May 1;438(1):114049
Experimental cell research 2024 May 1;438(1):114049
1-Benzylimidazole attenuates the stemness of breast cancer cells through partially targeting CYP4Z1.
Qin H, Zhou Y, Liu H, Yuan Y, Guo Q, Yuan M, Xi T, Zhang Y
Environmental toxicology 2024 Mar;39(3):1505-1520
Environmental toxicology 2024 Mar;39(3):1505-1520
LncRNA linc01194 promotes the progress of endometrial carcinoma by up-regulating SOX2 through binding to IGF2BP1.
Huang Z, Shen F, Chen J, Xie B, Chen X, Zhao Y, Chen S
Journal of gynecologic oncology 2024 Mar;35(2):e21
Journal of gynecologic oncology 2024 Mar;35(2):e21
OTUD7B knockdown inhibits the proliferation and stemness of breast cancer cells by destabilizing FOXM1.
Wang H, Han S, Xiao J, Fu X, Chen W, Zhuo D
Oncology letters 2024 Mar;27(3):102
Oncology letters 2024 Mar;27(3):102
Hapln1 promotes dedifferentiation and proliferation of iPSC-derived cardiomyocytes by promoting versican-based GDF11 trapping.
Hao DJ, Qin Y, Zhou SJ, Dong BH, Yang JS, Zou P, Wang LP, Zhao YT
Journal of pharmaceutical analysis 2024 Mar;14(3):335-347
Journal of pharmaceutical analysis 2024 Mar;14(3):335-347
Hinokitiol Inhibits Breast Cancer Cells In Vitro Stemness-Progression and Self-Renewal with Apoptosis and Autophagy Modulation via the CD44/Nanog/SOX2/Oct4 Pathway.
Chiang YF, Huang KC, Chen HY, Hamdy NM, Huang TC, Chang HY, Shieh TM, Huang YJ, Hsia SM
International journal of molecular sciences 2024 Mar 31;25(7)
International journal of molecular sciences 2024 Mar 31;25(7)
Establishment of an induced pluripotent stem cell (iPSC) line (INNDSUi004-A) from a patient with Congenital Nemaline Myopathy.
Wang Y, Liu W, Yang Y, Wang Y, Tang Y, Zhan Z, Sun X, Jiao Y, Shan D, Zhang R, Wang D, Sun P, Sun X, Yan C, Liu F
Stem cell research 2024 Jun;77:103435
Stem cell research 2024 Jun;77:103435
Generation of a control induced pluripotent stem cell line (SDUCHi001-A) from a healthy male donor.
Li C, Zhang F, Wang X, Chen M
Stem cell research 2024 Jun;77:103433
Stem cell research 2024 Jun;77:103433
Establishment of an induced pluripotent stem cell (iPSC) line (INNDSUi005-A) from a healthy female Chinese Han.
Liu W, Wang Y, Yang Y, Wang Y, Tang Y, Jiao Y, Shan D, Zhan Z, Zhang R, Wang D, Sun X, Sun P, Sun X, Yan C, Liu F
Stem cell research 2024 Jun;77:103386
Stem cell research 2024 Jun;77:103386
The small nucleolar RNA SNORA51 enhances breast cancer stem cell-like properties via the RPL3/NPM1/c-MYC pathway.
Li S, Jin Z, Song X, Ma J, Peng Z, Yu H, Song J, Zhang Y, Sun X, He M, Yu X, Jin F, Zheng A
Molecular carcinogenesis 2024 Jun;63(6):1117-1132
Molecular carcinogenesis 2024 Jun;63(6):1117-1132
Cysteine and glycine-rich protein 2 is crucial for maintaining the malignant phenotypes of gliomas through its action on Notch signalling cascade.
Liu L, Li F, Zhang L, Cheng Y, Wu L, Tie R, Jiang X, Gao W, Liu B, Wei Y, Chang P, Xu J, Zhao H, Zhang L
Toxicology and applied pharmacology 2024 Jun;487:116969
Toxicology and applied pharmacology 2024 Jun;487:116969
Clinicopathological significance of cancer stem cell marker CD44/SOX2 in esophageal squamous cell carcinoma (ESCC) patients and construction of a nomogram to predict overall survival.
Tian S, Ma R, Liu Y, Chen F, Huang X, Yang Q, Nian W, Fan Z
Translational cancer research 2024 Jun 30;13(6):2971-2984
Translational cancer research 2024 Jun 30;13(6):2971-2984
GD2 and its biosynthetic enzyme GD3 synthase promote tumorigenesis in prostate cancer by regulating cancer stem cell behavior.
Bhat AM, Mohapatra BC, Luan H, Mushtaq I, Chakraborty S, Kumar S, Wu W, Nolan B, Dutta S, Storck MD, Schott M, Meza JL, Lele SM, Lin MF, Cook LM, Corey E, Morrissey C, Coulter DW, Rowley MJ, Natarajan A, Datta K, Band V, Band H
Scientific reports 2024 Jun 12;14(1):13523
Scientific reports 2024 Jun 12;14(1):13523
Superb Silk Hydrogels with High Adaptability, Bioactivity, and Versatility Enabled by Photo-Cross-Linking.
Huang R, Hua J, Ru M, Yu M, Wang L, Huang Y, Yan S, Zhang Q, Xu W
ACS nano 2024 Jun 11;18(23):15312-15325
ACS nano 2024 Jun 11;18(23):15312-15325
Huaier enhances the tumor-killing effect and reverses gemcitabine-induced stemness by suppressing FoxM1.
Wang Q, Gong M, Liu R, Mo J, Bai R, An R, Wang X, Han L, Wang Z, Ma Q, Wu Z, Zhou C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155656
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155656
Identification of signaling pathways that specify a subset of migrating enteric neural crest cells at the wavefront in mouse embryos.
Zhou B, Feng C, Sun S, Chen X, Zhuansun D, Wang D, Yu X, Meng X, Xiao J, Wu L, Wang J, Wang J, Chen K, Li Z, You J, Mao H, Yang S, Zhang J, Jiao C, Li Z, Yu D, Wu X, Zhu T, Yang J, Xiang L, Liu J, Chai T, Shen J, Mao CX, Hu J, Hao X, Xiong B, Zheng S, Liu Z, Feng J
Developmental cell 2024 Jul 8;59(13):1689-1706.e8
Developmental cell 2024 Jul 8;59(13):1689-1706.e8
TAX1BP1 and FIP200 orchestrate non-canonical autophagy of p62 aggregates for mouse neural stem cell maintenance.
Zhu YF, Yu RH, Zhou S, Tang PP, Zhang R, Wu YX, Xu R, Wei JM, Wang YY, Zhang JL, Li MK, Shi XJ, Zhang YW, Liu GZ, Thorne RF, Zhang XD, Wu M, Chen S
Zoological research 2024 Jul 18;45(4):937-950
Zoological research 2024 Jul 18;45(4):937-950
The demethylase ALKBH5 mediates ZKSCAN3 expression through the m(6)A modification to activate VEGFA transcription and thus participates in MNNG-induced gastric cancer progression.
Wang Q, Huang Y, Jiang M, Tang Y, Wang Q, Bai L, Yu C, Yang X, Ding K, Wang W, Bai J, Chen Y
Journal of hazardous materials 2024 Jul 15;473:134690
Journal of hazardous materials 2024 Jul 15;473:134690
TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis.
Hao XL, Lv YF, Li DF, Bai FH, Gong J, Pan GQ, Su LX, Wang YL, Fu WL, Liu B, Huang L, Yan D, Tan QL, Liu JY, Guo QN
Journal of translational medicine 2024 Jan 2;22(1):6
Journal of translational medicine 2024 Jan 2;22(1):6
PKCiota Inhibits the Ferroptosis of Esophageal Cancer Cells via Suppressing USP14-Mediated Autophagic Degradation of GPX4.
Tao H, Song SJ, Fan ZW, Li WT, Jin X, Jiang W, Bai J, Shi ZZ
Antioxidants (Basel, Switzerland) 2024 Jan 17;13(1)
Antioxidants (Basel, Switzerland) 2024 Jan 17;13(1)
Prolonged exposure of environmental concentration benzo[a]pyrene promoted cancer stemness through AhR/PKA/SOX2 dependent pathway in small cell lung cancer.
Ni H, Tang S, Yuan X, Xu J, Zheng F, Chen K, Liu X, Zhang H, Hu J, Xia D, Wu Y
The Science of the total environment 2024 Jan 1;906:167824
The Science of the total environment 2024 Jan 1;906:167824
Epigenetic inhibition of CTCF by HN1 promotes dedifferentiation and stemness of anaplastic thyroid cancer.
Pan Z, Lu X, Xu T, Chen J, Bao L, Li Y, Gong Y, Che Y, Zou X, Tan Z, Huang P, Ge M
Cancer letters 2024 Jan 1;580:216496
Cancer letters 2024 Jan 1;580:216496
Exosomal circ_0037104 derived from Hu-MSCs inhibits cholangiocarcinoma progression by sponging miR-620 and targeting AFAP1.
Yuan Z, Xiong B, Liu L, Lu Y, Liu Y, Wang G, Qian Y, Diao B, Tu M
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23656
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23656
Tumor suppressor miR-361-3p inhibits prostate cancer progression through Gli1 and AKT/mTOR signaling pathway.
Wang S, Huang X, Zhang G, Chen Z, Guan H, Zhou W
Cellular signalling 2024 Feb;114:110998
Cellular signalling 2024 Feb;114:110998
EBF1 Limits the Numbers of Cochlear Hair and Supporting Cells and Forms the Scala Tympani and Spiral Limbus during Inner Ear Development.
Kagoshima H, Ohnishi H, Yamamoto R, Yasumoto A, Tona Y, Nakagawa T, Omori K, Yamamoto N
The Journal of neuroscience : the official journal of the Society for Neuroscience 2024 Feb 14;44(7)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2024 Feb 14;44(7)
Generation of the TSHSUi002-A induced pluripotent stem cell line from a patient with Peutz-Jeghers syndrome carring STK11 gene mutation.
Chen W, Wang H, Zhu K, Wang T, Yu W, Wu Q
Stem cell research 2024 Dec;81:103618
Stem cell research 2024 Dec;81:103618
Six induced pluripotent stem cell lines from fibroblasts of individuals with CLN3-related conditions.
Dwojak E, O'Mard D, Zou J, Wassif CA, Burkett S, Eckhaus M, Rueda Faucz F, Padilla C, Villasmil R, Zheng W, Dang Do AN
Stem cell research 2024 Dec;81:103563
Stem cell research 2024 Dec;81:103563
Fibroblast growth factor 2 enhances BMSC stemness through ITGA2-dependent PI3K/AKT pathway activation.
Jiang N, Hu Z, Wang Q, Hao J, Yang R, Jiang J, Wang H
Journal of cellular physiology 2024 Dec;239(12):e31423
Journal of cellular physiology 2024 Dec;239(12):e31423
Comprehensive gene set enrichment and variation analyses identify SUV39H1 as a potential prognostic biomarker for glioblastoma immunorelevance.
Liu J, Luo Q, Zhao H, Yang M, Yang J, Wang Y, Zhao M, Mao J, Chen J, Guo B, Zhang L
Computational and structural biotechnology journal 2024 Dec;23:4161-4176
Computational and structural biotechnology journal 2024 Dec;23:4161-4176
Phytosesquiterpene lactones deregulate mitochondrial activity and phenotypes associated with triple-negative breast cancer metastasis.
Cheng YT, Chang DM, Tung YC, Hsiao PW, Nakagawa-Goto K, Shyur LF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156226
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156226
CENPA facilitates glioma stem cell stemness and suppress ferroptosis to accelerate glioblastoma multiforme progression by promoting GBP2 transcription.
Li C, Jing J, Wang Y, Jiang H
Pathology, research and practice 2024 Aug;260:155438
Pathology, research and practice 2024 Aug;260:155438
Digirseophene A promotes recovery in injured developing cerebellum via AMPK/AKT/GSK3β pathway-mediated neural stem cell proliferation.
Tang X, Huang Y, Fu W, Wang P, Feng L, Yang J, Zhu H, Huang X, Ming Q, Li P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117046
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117046
Microbial reconstitution reverses prenatal stress-induced cognitive impairment and synaptic deficits in rat offspring.
Chen J, Zeng R, Chen H, Cao M, Peng Y, Tong J, Huang J
Brain, behavior, and immunity 2024 Aug;120:231-247
Brain, behavior, and immunity 2024 Aug;120:231-247
Identifying polyamine related biomarkers in diagnosis and treatment of ulcerative colitis by integrating bulk and single-cell sequencing data.
Wei W, Lu Y, Zhang M, Guo J, Zhang H
Scientific reports 2024 Aug 5;14(1):18094
Scientific reports 2024 Aug 5;14(1):18094
OTU deubiquitinase, ubiquitin aldehyde binding 2 (OTUB2) modulates the stemness feature, chemoresistance, and epithelial-mesenchymal transition of colon cancer via regulating GINS complex subunit 1 (GINS1) expression.
Zhu W, Wu C, Liu Z, Zhao S, Huang J
Cell communication and signaling : CCS 2024 Aug 29;22(1):420
Cell communication and signaling : CCS 2024 Aug 29;22(1):420
Unveiling the role of TAGLN2 in glioblastoma: From proneural-mesenchymal transition to Temozolomide resistance.
Li Y, Wang X, Xu T, Xu F, Chen T, Li Z, Wang Y, Chen H, Ming J, Cai J, Jiang C, Meng X
Cancer letters 2024 Aug 28;598:217107
Cancer letters 2024 Aug 28;598:217107
Biomineralization-Tuned Nanounits Reprogram the Signal Transducer and Activator of Transcription 3 Signaling for Ferroptosis-Immunotherapy in Cancer Stem Cells.
Zhao Y, Fei Y, Zhao Y, Li M, Hu Y, Cai K, Yu SH, Luo Z
ACS nano 2024 Aug 13;18(32):21268-21287
ACS nano 2024 Aug 13;18(32):21268-21287
M6A-methylated circPOLR2B forms an R-loop and regulates the biological behavior of glioma stem cells through positive feedback loops.
Lin H, Cui Z, E T, Xu H, Wang D, Wang P, Ruan X, Liu L, Xue Y
Cell death & disease 2024 Aug 1;15(8):554
Cell death & disease 2024 Aug 1;15(8):554
N-linked α2,6-sialylation of integrin β1 by the sialyltransferase ST6Gal1 promotes cell proliferation and stemness in gestational trophoblastic disease.
Liu J, Dong X, Xie R, Tang Y, Thomas AM, Li S, Liu S, Yu M, Qin H
Placenta 2024 Apr;149:18-28
Placenta 2024 Apr;149:18-28
The Natural Product Secoemestrin C Inhibits Colorectal Cancer Stem Cells via p38-S100A8 Feed-Forward Regulatory Loop.
Zhou H, Chen M, Zhao C, Shao R, Xu Y, Zhao W
Cells 2024 Apr 3;13(7)
Cells 2024 Apr 3;13(7)
GD2 and its biosynthetic enzyme GD3 synthase promote tumorigenesis in prostate cancer by regulating cancer stem cell behavior.
Bhat AM, Mohapatra BC, Luan H, Mushtaq I, Chakraborty S, Kumar S, Wu W, Nolan B, Dutta S, Stock MD, Schott M, Meza JL, Lele SM, Lin MF, Cook LM, Corey E, Morrissey C, Coulter DW, Rowley J, Natarajan A, Datta K, Band V, Band H
bioRxiv : the preprint server for biology 2024 Apr 22;
bioRxiv : the preprint server for biology 2024 Apr 22;
The Role of Purine Metabolism-Related Genes PPAT and IMPDH1 in the Carcinogenesis of Intrahepatic Cholangiocarcinoma Based on Metabonomic and Bioinformatic Analyses.
Liu CJ, Ma ZZ, Gong WZ, Mao XH, Wen HQ, Wang XH
Journal of oncology 2023;2023:5141836
Journal of oncology 2023;2023:5141836
Extracellular vesicles carrying miR-6836 derived from resistant tumor cells transfer cisplatin resistance of epithelial ovarian cancer via DLG2-YAP1 signaling pathway.
Zou Y, Zhao Z, Wang J, Ma L, Liu Y, Sun L, Song Y
International journal of biological sciences 2023;19(10):3099-3114
International journal of biological sciences 2023;19(10):3099-3114
Characterization of immature ovarian teratomas through single-cell transcriptome.
Cao M, Deng Y, Deng Y, Wu J, Yang C, Wang Z, Hou Q, Fu H, Ren Z, Xia X, Li Y, Wang W, Xu H, Liao X, Shu Y
Frontiers in immunology 2023;14:1131814
Frontiers in immunology 2023;14:1131814
Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study.
Li Y, Yang X, Wang F, Zhao J, Zhang C, Wu D, Yang B, Gao R, Zhao P, Zan Y, Su M, He Z, Liu Y, Wang J, Tang D
Frontiers in pharmacology 2023;14:1076815
Frontiers in pharmacology 2023;14:1076815
NPM1 promotes nasopharyngeal carcinoma metastasis and stemness by recruiting Mdm2 to induce the ubiquitination-mediated degradation of p53.
Hu L, Gong P, Zhou N, Wang S, He C, Zhou Y, Li Q, Zhao X, Peng H
American journal of cancer research 2023;13(5):1766-1785
American journal of cancer research 2023;13(5):1766-1785
MOGS promotes stemness acquisition and invasion via enhancing NOTCH1-glycosylation dependent NOTCH pathway in colorectal cancer.
Zhou S, Huang H, Zheng Z, Zheng K, Xie L
American journal of cancer research 2023;13(12):5996-6010
American journal of cancer research 2023;13(12):5996-6010
YAP1 affects the prognosis through the regulation of stemness in endometrial cancer.
Kong W, Huang Y, Jiang P, Tu Y, Li N, Wang J, Zhou Q, Zheng Y, Gou S, Tian C, Yuan R
PeerJ 2023;11:e15891
PeerJ 2023;11:e15891
Generation of an iPSC line (TSHSUi001-A) from a patient with Peutz-Jeghers syndrome due to STK11 mutation.
Wang T, Zhu K, Yu W, Peng L, Wang H, Wu Q
Stem cell research 2023 Sep;71:103152
Stem cell research 2023 Sep;71:103152
LncRNA PVT1 promotes strong stemness and endothelial progenitor cell characteristics in renal carcinoma stem cells.
Wang L, Yang G, Guo P, Lv Y, Fu B, Bai Y, Xiong F, Zhao D, Li C, Zhang J, Bai S, Zeng F, Xu W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23118
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23118
A novel TOX3-WDR5-ABCG2 signaling axis regulates the progression of colorectal cancer by accelerating stem-like traits and chemoresistance.
Hao J, Huang J, Hua C, Zuo Y, Yu W, Wu X, Li L, Xue G, Wan X, Ru L, Guo Z, Han S, Deng W, Lin F, Guo W
PLoS biology 2023 Sep;21(9):e3002256
PLoS biology 2023 Sep;21(9):e3002256
METTL3-stabilized super enhancers-lncRNA SUCLG2-AS1 mediates the formation of a long-range chromatin loop between enhancers and promoters of SOX2 in metastasis and radiosensitivity of nasopharyngeal carcinoma.
Hu X, Wu J, Feng Y, Ma H, Zhang E, Zhang C, Sun Q, Wang T, Ge Y, Zong D, Chen W, He X
Clinical and translational medicine 2023 Sep;13(9):e1361
Clinical and translational medicine 2023 Sep;13(9):e1361
Glioma-derived small extracellular vesicles induce pericyte-phenotype transition of glioma stem cells under hypoxic conditions.
Cheng Y, Li S, Hou Y, Wan W, Wang K, Fu S, Yuan Y, Yang K, Ye X
Cellular signalling 2023 Sep;109:110754
Cellular signalling 2023 Sep;109:110754
DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress.
Lin X, Liu YH, Zhang HQ, Wu LW, Li Q, Deng J, Zhang Q, Yang Y, Zhang C, Li YL, Hu J
Cancer cell international 2023 Sep 23;23(1):208
Cancer cell international 2023 Sep 23;23(1):208
Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice.
Wei P, Jia M, Kong X, Lyu W, Feng H, Sun X, Li J, Yang JJ
Stem cell research & therapy 2023 Sep 21;14(1):263
Stem cell research & therapy 2023 Sep 21;14(1):263
Biomimetic Microenvironmental Stiffness Boosts Stemness of Pancreatic Ductal Adenocarcinoma via Augmented Autophagy.
Gong T, Wu D, Pan H, Sun Z, Yao X, Wang D, Huang Y, Li X, Guo Y, Lu Y
ACS biomaterials science & engineering 2023 Sep 11;9(9):5347-5360
ACS biomaterials science & engineering 2023 Sep 11;9(9):5347-5360
Generation of an induced pluripotent stem cell line (SDASi001-A) from a Schimke immune-osseous dysplasia patient with SMARCAL1 mutations.
Wang X, Zhang H, Wang X, Zhou W, Dong L, Li N, He Q
Stem cell research 2023 Oct;72:103217
Stem cell research 2023 Oct;72:103217
Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer.
Yuan Q, Fan Y, Liu Z, Wang X, Jia M, Dong Y, Geng Z, Zheng J, Lu X
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1315-1331
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1315-1331
IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification.
Wu T, Liao L, Wu T, Chen S, Yi Q, Xu M
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2245-2263
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2245-2263
Fabrication of a Three-Dimensional Spheroid Culture System for Oral Squamous Cell Carcinomas Using a Microfabricated Device.
Ikeda-Motonakano R, Hirabayashi-Nishimuta F, Yada N, Yamasaki R, Nagai-Yoshioka Y, Usui M, Nakazawa K, Yoshiga D, Yoshioka I, Ariyoshi W
Cancers 2023 Oct 26;15(21)
Cancers 2023 Oct 26;15(21)
ADP Ribosylation Factor 4 (Arf4) Regulates Radial Migration through N-Cadherin Trafficking during Cerebral Cortical Development.
Hara Y, Katsuyama T, Fukaya M, Sugawara T, Shiroshima T, Sadakata T, Osumi N, Sakagami H
eNeuro 2023 Nov;10(11)
eNeuro 2023 Nov;10(11)
Histone lactylation-derived LINC01127 promotes the self-renewal of glioblastoma stem cells via the cis-regulating the MAP4K4 to activate JNK pathway.
Li L, Li Z, Meng X, Wang X, Song D, Liu Y, Xu T, Qin J, Sun N, Tian K, Zhong J, Yu D, Song Y, Hou T, Jiang C, Chen Q, Cai J
Cancer letters 2023 Nov 28;579:216467
Cancer letters 2023 Nov 28;579:216467
m6A modified BACE1-AS contributes to liver metastasis and stemness-like properties in colorectal cancer through TUFT1 dependent activation of Wnt signaling.
Wang X, Liu Y, Zhou M, Yu L, Si Z
Journal of experimental & clinical cancer research : CR 2023 Nov 21;42(1):306
Journal of experimental & clinical cancer research : CR 2023 Nov 21;42(1):306
Inhibiting MEK1 R189 citrullination enhances the chemosensitivity of docetaxel to multiple tumour cells.
Xue T, Fei S, Gu J, Li N, Zhang P, Liu X, Thompson PR, Zhang X
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2023 Nov 20;378(1890):20220246
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2023 Nov 20;378(1890):20220246
From Hair to the Brain: The Short-Term Therapeutic Potential of Human Hair Follicle-Derived Stem Cells and Their Conditioned Medium in a Rat Model of Stroke.
Karimi-Haghighi S, Pandamooz S, Jurek B, Fattahi S, Safari A, Azarpira N, Dianatpour M, Hooshmandi E, Bayat M, Owjfard M, Zafarmand SS, Mostaghel M, Mousavi SM, Jashire Nezhad N, Eraghi V, Fadakar N, Rahimi Jaberi A, Garcia-Esperon C, Spratt N, Levi C, Salehi MS, Borhani-Haghighi A
Molecular neurobiology 2023 May;60(5):2587-2601
Molecular neurobiology 2023 May;60(5):2587-2601
Nobiletin Mitigates D-Galactose-Induced Memory Impairment via Improving Hippocampal Neurogenesis in Mice.
Xiong W, Li R, Li B, Wang X, Wang H, Sun Y, Wang X, Li Y, Ren F
Nutrients 2023 May 8;15(9)
Nutrients 2023 May 8;15(9)
CircNFIX stimulates the proliferation, invasion, and stemness properties of ovarian cancer cells by enhancing SH3RF3 mRNA stability via binding LIN28B.
Yu XZ, Yang BW, Ao MY, Wu YK, Ye H, Wang RY, Xi MR, Hou MM
The Kaohsiung journal of medical sciences 2023 Mar;39(3):234-243
The Kaohsiung journal of medical sciences 2023 Mar;39(3):234-243
Neuroprotective effects of neural stem cells pretreated with neuregulin1β on PC12 cells exposed to oxygen-glucose deprivation/reoxygenation.
Zhai QY, Ye YH, Ren YQ, Song ZH, Ge KL, Cheng BH, Guo YL
Neural regeneration research 2023 Mar;18(3):618-625
Neural regeneration research 2023 Mar;18(3):618-625
EGFRvIII Promotes the Proneural-Mesenchymal Transition of Glioblastoma Multiforme and Reduces Its Sensitivity to Temozolomide by Regulating the NF-κB/ALDH1A3 Axis.
Shi ZF, Li GZ, Zhai Y, Pan CQ, Wang D, Yu MC, Liu C, Zhang W, Yu XG
Genes 2023 Mar 4;14(3)
Genes 2023 Mar 4;14(3)
Transgelin promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release.
Sun C, Zhang K, Ni C, Wan J, Duan X, Lou X, Yao X, Li X, Wang M, Gu Z, Yang P, Li Z, Qin Z
Oncogenesis 2023 Mar 29;12(1):18
Oncogenesis 2023 Mar 29;12(1):18
Generation of an induced pluripotent stem cell (iPSC) line (INNDSUi002-A) from a patient with riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency.
Zhang C, Wang D, Wang Y, Sun P, Zhao D, Zhao X, Zhao Y, Liu F, Xu J, Yan C
Stem cell research 2023 Jun;69:103067
Stem cell research 2023 Jun;69:103067
MicroRNA26a Overexpression Hastens Osteoblast Differentiation Capacity in Dental Stem Cells.
Kaufman S, Chang P, Pendleton E, Chandar N
Cellular reprogramming 2023 Jun;25(3):109-120
Cellular reprogramming 2023 Jun;25(3):109-120
MED27 plays a tumor-promoting role in breast cancer progression by targeting KLF4.
Wang R, Yu W, Zhu T, Lin F, Hua C, Ru L, Guo P, Wan X, Xue G, Guo Z, Han S, Lv K, Zhang G, Ge H, Guo W, Xu L, Deng W
Cancer science 2023 Jun;114(6):2277-2292
Cancer science 2023 Jun;114(6):2277-2292
SLC1A5 regulates cell proliferation and self-renewal through β-catenin pathway mediated by redox signaling in arsenic-treated uroepithelial cells.
Li S, Pei L, Zhou Q, Fu Z, Zhang L, Liu P, Yan N, Xi S
Ecotoxicology and environmental safety 2023 Jun 30;262:115204
Ecotoxicology and environmental safety 2023 Jun 30;262:115204
HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.
Ma H, Qi G, Han F, Gai P, Peng J, Kong B
Cell communication and signaling : CCS 2023 Jun 16;21(1):144
Cell communication and signaling : CCS 2023 Jun 16;21(1):144
Plasmalogen Improves Memory Function by Regulating Neurogenesis in a Mouse Model of Alzheimer's Diseases.
Li R, Xiong W, Li B, Li Y, Fang B, Wang X, Ren F
International journal of molecular sciences 2023 Jul 31;24(15)
International journal of molecular sciences 2023 Jul 31;24(15)
Induced neural stem cells suppressed neuroinflammation by inhibiting the microglial pyroptotic pathway in intracerebral hemorrhage rats.
Liu J, Cao C, Jin Y, Wang Y, Ma X, Li J, Guo S, Yang J, Niu J, Liang X
iScience 2023 Jul 21;26(7):107022
iScience 2023 Jul 21;26(7):107022
Ginsenoside Rg1 promotes astrocyte-to-neuron transdifferentiation in rat and its possible mechanism.
Shen K, Wu D, Sun B, Zhu Y, Wang H, Zou W, Ma Y, Lu Z
CNS neuroscience & therapeutics 2023 Jan;29(1):256-269
CNS neuroscience & therapeutics 2023 Jan;29(1):256-269
Isolation of Swine Bone Marrow Lin-/CD45-/CD133 + Cells and Cardio-protective Effects of its Exosomes.
Li H, Gu J, Sun X, Zuo Q, Li B, Gu X
Stem cell reviews and reports 2023 Jan;19(1):213-229
Stem cell reviews and reports 2023 Jan;19(1):213-229
The Adipokine Visfatin Modulates Cancer Stem Cell Properties in Triple-Negative Breast Cancer.
Chiang YF, Huang KC, Chen HY, Huang TC, Ali M, Chang HY, Shieh TM, Shih YH, Wang KL, Huang YJ, Chung CP, Hsia SM
Biomedicines 2023 Jan 20;11(2)
Biomedicines 2023 Jan 20;11(2)
Core-shell SERS nanotags-based western blot.
Liu B, Tang H, Liu Q, Wang W, Li H, Zheng S, Sun F, Zhao X
Talanta 2023 Feb 1;253:123888
Talanta 2023 Feb 1;253:123888
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
Wang R, Xu H, Tan B, Yi Q, Sun Y, Xiang H, Chen T, Liu H, Xie Q, Wang L, Tian J, Zhu J
Free radical biology & medicine 2023 Feb 1;195:270-282
Free radical biology & medicine 2023 Feb 1;195:270-282
USP10 promotes intrahepatic cholangiocarcinoma cell survival and stemness via SNAI1 deubiquitination.
Zhu W, Ye B, Yang S, Li Y
Journal of molecular histology 2023 Dec;54(6):703-714
Journal of molecular histology 2023 Dec;54(6):703-714
Astragaloside IV enhances the sensitivity of breast cancer stem cells to paclitaxel by inhibiting stemness.
Huang P, Li H, Ren L, Xie H, Chen L, Liang Y, Hu Y, Selistre-de-Araujo HS, Boussios S, Jhawar SR, Cui R, Zuo Q, Chen Q
Translational cancer research 2023 Dec 31;12(12):3703-3717
Translational cancer research 2023 Dec 31;12(12):3703-3717
α5-nAChR/STAT3/CD47 axis contributed to nicotine-related lung adenocarcinoma progression and immune escape.
Kang G, Jiao Y, Pan P, Fan H, Li Q, Li X, Li J, Wang Y, Jia Y, Wang J, Sun H, Ma X
Carcinogenesis 2023 Dec 15;44(10-11):773-784
Carcinogenesis 2023 Dec 15;44(10-11):773-784
IL20RB signaling enhances stemness and chemotherapy resistance in pancreatic cancer.
Li XH, Huang GZ, Xu ZL, Zhao CY, Dong XY, Cui BK, Lin XJ
Journal of translational medicine 2023 Dec 14;21(1):911
Journal of translational medicine 2023 Dec 14;21(1):911
Metformin promotes cGAS/STING signaling pathway activation by blocking AKT phosphorylation in gastric cancer.
Shen Q, Yang L, Li C, Wang T, Lv J, Liu W, Lin Y, Yin Y, Tao K
Heliyon 2023 Aug;9(8):e18954
Heliyon 2023 Aug;9(8):e18954
USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.
Zhong B, Zhu Q, Wang L, Wang F, Zheng Y, Lin S, Cheng X
Cell biology international 2023 Aug;47(8):1368-1380
Cell biology international 2023 Aug;47(8):1368-1380
KIF15 knockdown inhibits the development of endometrial cancer by suppressing epithelial-mesenchymal transition and stemness through Wnt/β-catenin signaling.
Huang J, Sun X, Diao G, Li R, Guo J, Han J
Environmental toxicology 2023 Aug;38(8):1824-1834
Environmental toxicology 2023 Aug;38(8):1824-1834
B7-H3 confers stemness characteristics to gastric cancer cells by promoting glutathione metabolism through AKT/pAKT/Nrf2 pathway.
Xia L, Chen Y, Li J, Wang J, Shen K, Zhao A, Jin H, Zhang G, Xi Q, Xia S, Shi T, Li R
Chinese medical journal 2023 Aug 20;136(16):1977-1989
Chinese medical journal 2023 Aug 20;136(16):1977-1989
NeuroD4 converts glioblastoma cells into neuron-like cells through the SLC7A11-GSH-GPX4 antioxidant axis.
Wang H, Zhao P, Zhang Y, Chen Z, Bao H, Qian W, Wu J, Xing Z, Hu X, Jin K, Zhuge Q, Yang J
Cell death discovery 2023 Aug 15;9(1):297
Cell death discovery 2023 Aug 15;9(1):297
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Lu J, Yang X, He C, Chen Y, Li C, Li S, Chen Y, Wu Y, Xiang Z, Kang J, Jiang G, Wang C, Diarra MD, He R, Feng G, Yan R
Acta biomaterialia 2023 Apr 15;161:80-99
Acta biomaterialia 2023 Apr 15;161:80-99
Palmitoyl transferases act as novel drug targets for pancreatic cancer.
Lin Z, Lv Z, Liu X, Huang K
Journal of translational medicine 2023 Apr 10;21(1):249
Journal of translational medicine 2023 Apr 10;21(1):249
Metformin Promotes the Hair-Inductive Activity of Three-Dimensional Aggregates of Epidermal and Dermal Cells Self-Assembled in vitro.
Sun C, Hu SH, Dong BQ, Jiang S, Miao F, Lei TC
Skin pharmacology and physiology 2022;35(3):137-147
Skin pharmacology and physiology 2022;35(3):137-147
Antitumor Effect of Si-Jun-Zi Decoction on SGC7901 Gastric Cancer Cells by CMTM2 Activation.
Li X, Chen W, Miao L, Sun H, Gao X, Guo S, Zhang Y, Yang Y, Guo J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4675815
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4675815
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.
Wang X, Li Y, Li Y, Liu P, Liu S, Pan Y
Stem cells international 2022;2022:3242482
Stem cells international 2022;2022:3242482
Selected Histone Deacetylase Inhibitors Reverse the Frataxin Transcriptional Defect in a Novel Friedreich's Ataxia Induced Pluripotent Stem Cell-Derived Neuronal Reporter System.
Schreiber AM, Li Y, Chen YH, Napierala JS, Napierala M
Frontiers in neuroscience 2022;16:836476
Frontiers in neuroscience 2022;16:836476
Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model.
Sun W, Wen M, Liu M, Wang Q, Liu Q, Li L, Siebert HC, Loers G, Zhang R, Zhang N
Frontiers in aging neuroscience 2022;14:1075161
Frontiers in aging neuroscience 2022;14:1075161
LASS2 impairs proliferation of glioma stem cells and migration and invasion of glioma cells mainly via inhibition of EMT and apoptosis promotion.
Zhao WJ, Fan YP, Ou GY, Qiao XY
Journal of Cancer 2022;13(7):2281-2292
Journal of Cancer 2022;13(7):2281-2292
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling.
Peng P, Zhu H, Liu D, Chen Z, Zhang X, Guo Z, Dong M, Wan L, Zhang P, Liu G, Zhang S, Dong F, Hu F, Cheng F, Huang S, Guo D, Zhang B, Yu X, Wan F
Theranostics 2022;12(9):4221-4236
Theranostics 2022;12(9):4221-4236
Prrx1 promotes resistance to temozolomide by upregulating ABCC1 and inducing vasculogenic mimicry in glioma.
Chen Z, Zhang Y, Chen Y, Lin W, Zhang Y, Cai G, Sun X, Zheng K, He J, Ai T, Wang J, Zhao L, Ke Y
American journal of cancer research 2022;12(8):3892-3912
American journal of cancer research 2022;12(8):3892-3912
hsa_circ_0001741 promotes esophageal squamous cell carcinoma stemness, invasion and migration by sponging miR-491-5p to upregulate NOTCH3 expression.
Li L, Lei K, Lyu Y, Tan B, Liang R, Wu D, Wang K, Wang W, Lin H, Wang M
American journal of cancer research 2022;12(5):2012-2031
American journal of cancer research 2022;12(5):2012-2031
Lgr5(+) cells are required and dynamically participate in olfactory epithelium regeneration: a revisiting shows Lgr5 expression in multiple cell lineages.
Ren W, Ma Z, Wang L, Feng X, Yu H, Yu Y
Theranostics 2022;12(13):5631-5644
Theranostics 2022;12(13):5631-5644
ISG15 enhances glioma cell stemness by promoting Oct4 protein stability.
Dai Y, Yu T, Yu C, Lu T, Zhou L, Cheng C, Ni H
Environmental toxicology 2022 Sep;37(9):2133-2142
Environmental toxicology 2022 Sep;37(9):2133-2142
ΔNp63α mediates sulforaphane suppressed colorectal cancer stem cell properties through transcriptional regulation of Nanog/Oct4/Sox2.
Chen Y, Wang MH, Wu JY, Zhu JY, Xie CF, Li XT, Wu JS, Geng SS, Li YD, Han HY, Zhong CY
The Journal of nutritional biochemistry 2022 Sep;107:109067
The Journal of nutritional biochemistry 2022 Sep;107:109067
High-efficiency brain-targeted intranasal delivery of BDNF mediated by engineered exosomes to promote remyelination.
Zhai Y, Wang Q, Zhu Z, Hao Y, Han F, Hong J, Zheng W, Ma S, Yang L, Cheng G
Biomaterials science 2022 Sep 27;10(19):5707-5718
Biomaterials science 2022 Sep 27;10(19):5707-5718
miR-124- and let-7-Mediated Reprogram of Human Fibroblasts into SST Interneurons.
Gu X, Wang J, Jiang X
ACS chemical neuroscience 2022 Sep 21;13(18):2755-2765
ACS chemical neuroscience 2022 Sep 21;13(18):2755-2765
GDF15 Contributes to Radioresistance by Mediating the EMT and Stemness of Breast Cancer Cells.
Zhao X, Liu X, Hu S, Pan Y, Zhang J, Tai G, Shao C
International journal of molecular sciences 2022 Sep 18;23(18)
International journal of molecular sciences 2022 Sep 18;23(18)
CAFs-secreted exosomal cricN4BP2L2 promoted colorectal cancer stemness and chemoresistance by interacting with EIF4A3.
Qu Z, Yang KD, Luo BH, Zhang F
Experimental cell research 2022 Sep 15;418(2):113266
Experimental cell research 2022 Sep 15;418(2):113266
Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer.
Katayama KI, Zheng Y, Inoue N
Scientific reports 2022 Sep 1;12(1):14848
Scientific reports 2022 Sep 1;12(1):14848
PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop.
Zhao X, Shu D, Sun W, Si S, Ran W, Guo B, Cui L
Cancer communications (London, England) 2022 Oct;42(10):987-1007
Cancer communications (London, England) 2022 Oct;42(10):987-1007
Long non-coding RNA NRSN2-AS1, transcribed by SOX2, promotes progression of esophageal squamous cell carcinoma by regulating the ubiquitin-degradation of PGK1.
Xu T, Yan Z, Lu J, Chen L, Li X, Li Y, Dong Z, Guo W
Clinical & experimental metastasis 2022 Oct;39(5):757-769
Clinical & experimental metastasis 2022 Oct;39(5):757-769
Rspondin-1 contributes to the progression and stemness of gastric cancer by LGR5.
Wang C, Gao Y, Liang W, Lu Y, Zhang K, Wu D, Zhuang Z, Li K, Qiao Z, Xi H, Chen L
Biochemical and biophysical research communications 2022 Oct 30;627:91-96
Biochemical and biophysical research communications 2022 Oct 30;627:91-96
Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer.
Myint K, Chuang LSH, Teh YX, Mawan NA, Shi EJ, Mok MMH, Nuttonmanit N, Matsuo J, Li Y, Yang H, Okabe A, Kaneda A, Osato M, So JB, Yong WP, Tan P, Yeoh KG, Ito Y
iScience 2022 Oct 21;25(10):105194
iScience 2022 Oct 21;25(10):105194
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
Tian H, Chen Z, Zhu X, Ou Q, Wang Z, Wu B, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Lu L, Xu GT
iScience 2022 Oct 21;25(10):105050
iScience 2022 Oct 21;25(10):105050
A three-dimensional matrix system containing melatonin and neural stem cells repairs damage from traumatic brain injury in rats.
Fang XY, Zhao DW, Zhang C, Ge HF, Zhang XY, Zhao FC, Jiang YB, Feng H, Hu R
Neural regeneration research 2022 Nov;17(11):2512-2517
Neural regeneration research 2022 Nov;17(11):2512-2517
FAM64A promotes HNSCC tumorigenesis by mediating transcriptional autoregulation of FOXM1.
Zhao X, Chen H, Qiu Y, Cui L
International journal of oral science 2022 May 10;14(1):25
International journal of oral science 2022 May 10;14(1):25
Claudin1 decrease induced by 1,25-dihydroxy-vitamin D3 potentiates gefitinib resistance therapy through inhibiting AKT activation-mediated cancer stem-like properties in NSCLC cells.
Jia Z, Wang K, Duan Y, Hu K, Zhang Y, Wang M, Xiao K, Liu S, Pan Z, Ding X
Cell death discovery 2022 Mar 18;8(1):122
Cell death discovery 2022 Mar 18;8(1):122
Transplantation of Human Umbilical Cord Mesenchymal Stem Cells-Derived Neural Stem Cells Pretreated with Neuregulin1β Ameliorate Cerebral Ischemic Reperfusion Injury in Rats.
Zhai QY, Ren YQ, Ni QS, Song ZH, Ge KL, Guo YL
Biomolecules 2022 Mar 10;12(3)
Biomolecules 2022 Mar 10;12(3)
Poly(I:C) exposure during in vitro fertilization disrupts first cleavage of mouse embryos and subsequent blastocyst development.
Wang Z, Chen S, Zhang Y, Su C, Liao Y, Zhang S, Ren Y, Ye F, Zeng C, Zhou G, Xian H, Zhang M
Journal of reproductive immunology 2022 Jun;151:103635
Journal of reproductive immunology 2022 Jun;151:103635
A novel ALG10/TGF-β positive regulatory loop contributes to the stemness of colorectal cancer.
Xu X, Wang H, Li X, Duan X, Wang Y
Aging 2022 Jun 9;14(11):4858-4873
Aging 2022 Jun 9;14(11):4858-4873
SNAT2/SLC38A2 Confers the Stemness of Gastric Cancer Cells via Regulating Glutamine Level.
Nie K, Cai M
Digestive diseases and sciences 2022 Jul;67(7):2948-2956
Digestive diseases and sciences 2022 Jul;67(7):2948-2956
Generation of human induced pluripotent stem cell line from peripheral blood mononuclear cells from an activated phosphoinositide 3-kinase δ syndrome patient.
Fang S, Zeng A, Xu Q, Zhou L, Zhang Z, An Y, Zhao X
Stem cell research 2022 Jul;62:102822
Stem cell research 2022 Jul;62:102822
Establishment of an induced pluripotent stem cell (iPSC) line (INNDSUi001-A) from a healthy female Chinese Han.
Wang D, Zhang R, Wang Y, Sun P, Ji X, Sun X, Xu J, Zhao D, Yan C, Liu F
Stem cell research 2022 Jul;62:102819
Stem cell research 2022 Jul;62:102819
Generation of a human induced pluripotent stem cell line (INNDSUi003-A) derived from patient with Becker muscular dystrophy (BMD).
Ji X, Wang Y, Sun P, Wang D, Sun X, Zhang R, Xu J, Li W, Liu F, Yan C
Stem cell research 2022 Jul;62:102794
Stem cell research 2022 Jul;62:102794
miR-3682-3p directly targets FOXO3 and stimulates tumor stemness in hepatocellular carcinoma via a positive feedback loop involving FOXO3/PI3K/AKT/c-Myc.
Chen Q, Yang SB, Zhang YW, Han SY, Jia L, Li B, Zhang Y, Zuo S
World journal of stem cells 2022 Jul 26;14(7):539-555
World journal of stem cells 2022 Jul 26;14(7):539-555
Expansion of mouse castration-resistant intermediate prostate stem cells in vitro.
Xu Y, Mu J, Zhou Z, Leng Y, Yu Y, Song X, Liu A, Zhu H, Li J, Wang D
Stem cell research & therapy 2022 Jul 15;13(1):299
Stem cell research & therapy 2022 Jul 15;13(1):299
tRF-19-W4PU732S promotes breast cancer cell malignant activity by targeting inhibition of RPL27A (ribosomal protein-L27A).
Zhang Z, Liu Z, Zhao W, Zhao X, Tao Y
Bioengineered 2022 Feb;13(2):2087-2098
Bioengineered 2022 Feb;13(2):2087-2098
Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer.
Wei J, Zheng X, Li W, Li X, Fu Z
Cancer cell international 2022 Feb 11;22(1):75
Cancer cell international 2022 Feb 11;22(1):75
Endothelial cell-derived S1P promotes migration and stemness by binding with GPR63 in colorectal cancer.
Zeng S, Liang Y, Hu H, Wang F, Liang L
Pathology, research and practice 2022 Dec;240:154197
Pathology, research and practice 2022 Dec;240:154197
ALG2 inhibits the epithelial-to-mesenchymal transition and stemness of ovarian granulosa cells through the Wnt/β-catenin signaling pathway in polycystic ovary syndrome.
Zheng Q, Liu M, Fu J
Reproductive biology 2022 Dec;22(4):100706
Reproductive biology 2022 Dec;22(4):100706
Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization.
Yuan Y, Yao H, Zhou M, Ma X, Zhou Y, Xu J, Niu M, Yin J, Zheng L, Xu S
Journal of medicinal chemistry 2022 Dec 8;65(23):15749-15769
Journal of medicinal chemistry 2022 Dec 8;65(23):15749-15769
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Li M, Song D, Chen X, Wang X, Xu L, Yang M, Yang J, Kalvakolanu DV, Wei X, Liu X, Li Y, Guo B, Zhang L
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
CRISPR/Cas9-mediated genetic correction reverses spinocerebellar ataxia 3 disease-associated phenotypes in differentiated cerebellar neurons.
Song G, Ma Y, Gao X, Zhang X, Zhang F, Tian C, Hou J, Liu Z, Zhao Z, Tian Y
Life medicine 2022 Aug;1(1):27-44
Life medicine 2022 Aug;1(1):27-44
Inhibitory effect of the novel tyrosine kinase inhibitor DCC-2036 on triple-negative breast cancer stem cells through AXL-KLF5 positive feedback loop.
Shen Y, Zhu Q, Xiao M, Yin L, Feng W, Feng J, He J, Li P, Chen X, Ding W, Zhong J, Zeng Z, Xie Z, Liu J, Zu X
Cell death & disease 2022 Aug 30;13(8):749
Cell death & disease 2022 Aug 30;13(8):749
Neural, adipocyte and hepatic differentiation potential of primary and secondary hair follicle stem cells isolated from Arbas Cashmere goats.
Yan W, Hao F, Zhe X, Wang Y, Liu D
BMC veterinary research 2022 Aug 15;18(1):313
BMC veterinary research 2022 Aug 15;18(1):313
CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma.
Wang J, Zhou Y, Zhang D, Zhao W, Lu Y, Liu C, Lin W, Zhang Y, Chen K, Wang H, Zhao L
The EMBO journal 2022 Aug 1;41(15):e110218
The EMBO journal 2022 Aug 1;41(15):e110218
Establishment of iPS cell line (KLRMMEi002-A) by reprogramming peripheral blood mononuclear cells from a patient with USH2A-associated Usher syndrome.
Liang L, Xue Y, Su C, Wang J, Chen L, Su T, Ke J, Xie L, Cui Z, Yu Q, Chan HF, Zhong J, Guo Y, Chen J
Stem cell research 2022 Apr;60:102699
Stem cell research 2022 Apr;60:102699
MicroRNA-18 facilitates the stemness of gastric cancer by downregulating HMGB3 though targeting Meis2.
Zhang Y, Lin W, Jiang W, Wang Z
Bioengineered 2022 Apr;13(4):9959-9972
Bioengineered 2022 Apr;13(4):9959-9972
SNORD1C maintains stemness and 5-FU resistance by activation of Wnt signaling pathway in colorectal cancer.
Liu Y, Zhao C, Wang G, Chen J, Ju S, Huang J, Wang X
Cell death discovery 2022 Apr 14;8(1):200
Cell death discovery 2022 Apr 14;8(1):200
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis.
Liu Z, Lu J, Fang H, Sheng J, Cui M, Yang Y, Tang B, Zhang X
Frontiers in cell and developmental biology 2021;9:783385
Frontiers in cell and developmental biology 2021;9:783385
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Cao W, Li Y, Sun H, Yang C, Zhu J, Xie C, Li X, Wu J, Geng S, Wang L, Sun L, Geng G, Han H, Zhong C
Frontiers in cell and developmental biology 2021;9:679806
Frontiers in cell and developmental biology 2021;9:679806
Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.
Cui X, Qin T, Zhao Z, Yang G, Sanches JGP, Zhang Q, Fan S, Cao L, Hu X
Journal of Cancer 2021;12(15):4686-4697
Journal of Cancer 2021;12(15):4686-4697
Blockade of deubiquitinating enzyme PSMD14 overcomes chemoresistance in head and neck squamous cell carcinoma by antagonizing E2F1/Akt/SOX2-mediated stemness.
Jing C, Duan Y, Zhou M, Yue K, Zhuo S, Li X, Liu D, Ye B, Lai Q, Li L, Yao X, Wei H, Zhang W, Wu Y, Wang X
Theranostics 2021;11(6):2655-2669
Theranostics 2021;11(6):2655-2669
IL20RA signaling enhances stemness and promotes the formation of an immunosuppressive microenvironment in breast cancer.
Gao W, Wen H, Liang L, Dong X, Du R, Zhou W, Zhang X, Zhang C, Xiang R, Li N
Theranostics 2021;11(6):2564-2580
Theranostics 2021;11(6):2564-2580
Regulatory T cells promote glioma cell stemness through TGF-β-NF-κB-IL6-STAT3 signaling.
Liu S, Zhang C, Wang B, Zhang H, Qin G, Li C, Cao L, Gao Q, Ping Y, Zhang K, Lian J, Zhao Q, Wang D, Zhang Z, Zhao X, Yang L, Huang L, Yang B, Zhang Y
Cancer immunology, immunotherapy : CII 2021 Sep;70(9):2601-2616
Cancer immunology, immunotherapy : CII 2021 Sep;70(9):2601-2616
TAZ inhibits acinar cell differentiation but promotes immature ductal cell proliferation in adult mouse salivary glands.
Miyachi Y, Nishio M, Otani J, Matsumoto S, Kikuchi A, Mak TW, Maehama T, Suzuki A
Genes to cells : devoted to molecular & cellular mechanisms 2021 Sep;26(9):714-726
Genes to cells : devoted to molecular & cellular mechanisms 2021 Sep;26(9):714-726
Activation of bivalent factor DLX5 cooperates with master regulator TP63 to promote squamous cell carcinoma.
Huang Y, Yang Q, Zheng Y, Lin L, Xu X, Xu XE, Silva TC, Hazawa M, Peng L, Cao H, Ding Y, Lu D, Berman BP, Xu LY, Li EM, Yin D
Nucleic acids research 2021 Sep 20;49(16):9246-9263
Nucleic acids research 2021 Sep 20;49(16):9246-9263
An SETD1A/Wnt/β-catenin feedback loop promotes NSCLC development.
Wang R, Liu J, Li K, Yang G, Chen S, Wu J, Xie X, Ren H, Pang Y
Journal of experimental & clinical cancer research : CR 2021 Oct 13;40(1):318
Journal of experimental & clinical cancer research : CR 2021 Oct 13;40(1):318
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Feng X, Cao A, Qin T, Zhang Q, Fan S, Wang B, Song B, Yu X, Li L
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
Immunohistochemical evidence for adult human neurogenesis in health and disease.
Gault N, Szele FG
WIREs mechanisms of disease 2021 Nov;13(6):e1526
WIREs mechanisms of disease 2021 Nov;13(6):e1526
MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal.
Zhang Y, Ding H, Wang X, Wang X, Wan S, Xu A, Gan R, Ye SD
Cell reports 2021 Nov 2;37(5):109949
Cell reports 2021 Nov 2;37(5):109949
An iPS cell line SDUBMSi0011-A from a multiple epiphyseal dysplasia patient carrying c. 1076T > G mutation in the SMOC2 gene.
Long F, Liu X, Liu Y, Liu Q, Sun W
Stem cell research 2021 May;53:102353
Stem cell research 2021 May;53:102353
Generation of an induced pluripotent stem cell line SDUBMSi005-A from a patient with double primary gastric and colon carcinoma.
Li Y, Liu X, Chen D, Liu Y, Ma Y, Liu Q, Sun W, Li J
Stem cell research 2021 May;53:102253
Stem cell research 2021 May;53:102253
Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability.
Wu B, Yang C, Fang Y, Ding W, Zhang Y
Environmental toxicology 2021 May;36(5):840-849
Environmental toxicology 2021 May;36(5):840-849
CDR1as regulated by hnRNPM maintains stemness of periodontal ligament stem cells via miR-7/KLF4.
Gu X, Li X, Jin Y, Zhang Z, Li M, Liu D, Wei F
Journal of cellular and molecular medicine 2021 May;25(9):4501-4515
Journal of cellular and molecular medicine 2021 May;25(9):4501-4515
Apatinib suppresses lung cancer stem-like cells by complex interplay between β-catenin signaling and mitochondrial ROS accumulation.
Zhu J, Li X, Liang C, Zhou X, Ge M, Chen Y, Jin J, Yin J, Xu H, Xie C, Zhong C
Cell death discovery 2021 May 12;7(1):102
Cell death discovery 2021 May 12;7(1):102
Establishment of patient-specific induced pluripotent stem cell line SDUBMSi009-A from a patient with X-linked Lowe syndrome.
Liu X, Liu Y, Ma Y, Gong Y, Liu Q, Sun W, Guo H
Stem cell research 2021 Mar;51:102171
Stem cell research 2021 Mar;51:102171
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation.
Bian X, Shi D, Xing K, Zhou H, Lu L, Yu D, Wu W
Clinical and translational medicine 2021 Mar;11(3):e352
Clinical and translational medicine 2021 Mar;11(3):e352
NRF2 is required for structural and metabolic maturation of human induced pluripotent stem cell-derived ardiomyocytes.
Zhang X, Ye L, Xu H, Zhou Q, Tan B, Yi Q, Yan L, Xie M, Zhang Y, Tian J, Zhu J
Stem cell research & therapy 2021 Mar 24;12(1):208
Stem cell research & therapy 2021 Mar 24;12(1):208
p97/VCP is highly expressed in the stem-like cells of breast cancer and controls cancer stemness partly through the unfolded protein response.
Li C, Huang Y, Fan Q, Quan H, Dong Y, Nie M, Wang J, Xie F, Ji J, Zhou L, Zheng Z, Wang L
Cell death & disease 2021 Mar 17;12(4):286
Cell death & disease 2021 Mar 17;12(4):286
Iguratimod-encapsulating PLGA-NPs induce human multiple myeloma cell death via reactive oxygen species and Caspase-dependent signalling.
Wang F, Younis M, Luo Y, Zhang L, Yuan L
International immunopharmacology 2021 Jun;95:107532
International immunopharmacology 2021 Jun;95:107532
SMAR1 attenuates the stemness of osteosarcoma cells via through suppressing ABCG2 transcriptional activity.
Xu H, Liu T, Li W, Yao Q
Environmental toxicology 2021 Jun;36(6):1090-1098
Environmental toxicology 2021 Jun;36(6):1090-1098
Chitinase-Like Protein Ym2 (Chil4) Regulates Regeneration of the Olfactory Epithelium via Interaction with Inflammation.
Wang L, Ren W, Li X, Zhang X, Tian H, Bhattarai JP, Challis RC, Lee AC, Zhao S, Yu H, Ma M, Yu Y
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jun 30;41(26):5620-5637
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jun 30;41(26):5620-5637
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Zhang K, Wang A, Zhong K, Qi S, Wei C, Shu X, Tu WY, Xu W, Xia C, Xiao Y, Chen A, Bai L, Zhang J, Luo B, Wang W, Shen C
Neuron 2021 Jun 16;109(12):1949-1962.e6
Neuron 2021 Jun 16;109(12):1949-1962.e6
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
Chen Z, Chen Y, Li Y, Lian W, Zheng K, Zhang Y, Zhang Y, Lin C, Liu C, Sun F, Sun X, Wang J, Zhao L, Ke Y
Cell death & disease 2021 Jun 15;12(6):615
Cell death & disease 2021 Jun 15;12(6):615
The stemness of hepatocytes is maintained by high levels of lipopolysaccharide via YAP1 activation.
Shao C, Yang X, Jing Y, Hou X, Huang Y, Zong C, Gao L, Liu W, Jiang J, Ye F, Shi J, Zhao Q, Li R, Zhang X, Wei L
Stem cell research & therapy 2021 Jun 10;12(1):342
Stem cell research & therapy 2021 Jun 10;12(1):342
The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis.
Wang F, Zhang L, Luo Y, Zhang Q, Zhang Y, Shao Y, Yuan L
Molecular neurobiology 2021 Jul;58(7):3362-3373
Molecular neurobiology 2021 Jul;58(7):3362-3373
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Shi Y, Jiang J, Cui Y, Chen Y, Dong T, An H, Liu P
DNA and cell biology 2021 Jan;40(1):93-100
DNA and cell biology 2021 Jan;40(1):93-100
Polychlorinated biphenyl quinone induced the acquisition of cancer stem cells properties and epithelial-mesenchymal transition through Wnt/β-catenin.
Qin Q, Yang B, Liu Z, Xu L, Song E, Song Y
Chemosphere 2021 Jan;263:128125
Chemosphere 2021 Jan;263:128125
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
Zuo X, Zhou J, Li Y, Wu K, Chen Z, Luo Z, Zhang X, Liang Y, Esteban MA, Zhou Y, Fu XD
Nature structural & molecular biology 2021 Feb;28(2):132-142
Nature structural & molecular biology 2021 Feb;28(2):132-142
A novel regulatory loop miR-101/ANXA2/EGR1 mediates malignant characteristics of liver cancer stem cells.
Ma S, Cheng J, Wang H, Ding N, Zhou F, Ji R, Zhu L, Zhu C, Pan Y
Carcinogenesis 2021 Feb 11;42(1):93-104
Carcinogenesis 2021 Feb 11;42(1):93-104
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
Yang J, Hu Y, Wang L, Sun X, Yu L, Guo W
Bioengineered 2021 Dec;12(2):11007-11017
Bioengineered 2021 Dec;12(2):11007-11017
SETD8 induces stemness and epithelial-mesenchymal transition of pancreatic cancer cells by regulating ROR1 expression.
Liu M, Shi Y, Hu Q, Qin Y, Ji S, Liu W, Zhuo Q, Fan G, Ye Z, Song C, Yu X, Xu X, Xu W
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1614-1624
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1614-1624
Alterations of DNA methylation were associated with the rapid growth of cortisol-producing adrenocortical adenoma during pregnancy.
Wang C, Sun Y, Yin X, Feng R, Feng R, Xu M, Liang K, Zhao R, Gu G, Jiang X, Su P, Zhang X, Liu J
Clinical epigenetics 2021 Dec 4;13(1):213
Clinical epigenetics 2021 Dec 4;13(1):213
Lysosome Fe(2+) release is responsible for etoposide- and cisplatin-induced stemness of small cell lung cancer cells.
Wang K, Chen X, Zuyi W, Chen L, Fu W
Environmental toxicology 2021 Aug;36(8):1654-1663
Environmental toxicology 2021 Aug;36(8):1654-1663
DEAD-box helicase 27 enhances stem cell-like properties with poor prognosis in breast cancer.
Li S, Ma J, Zheng A, Song X, Chen S, Jin F
Journal of translational medicine 2021 Aug 6;19(1):334
Journal of translational medicine 2021 Aug 6;19(1):334
Generation and characterization of an integration-free iPSC line SDUBMSi006-A from a patient with Alport syndrome caused by COL4A3 gene mutations.
Ma Y, Wang Z, Liu X, Sun W, Gong Y, Liu G, Sun G
Stem cell research 2021 Apr;52:102237
Stem cell research 2021 Apr;52:102237
5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells.
Sun X, Li H, Zhu Y, Xu P, Zuo Q, Li B, Gu X
Stem cells international 2020;2020:5162350
Stem cells international 2020;2020:5162350
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.
Yang B, Bai H, Sa Y, Zhu P, Liu P
Journal of Cancer 2020;11(8):2303-2317
Journal of Cancer 2020;11(8):2303-2317
Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features.
Mei Y, Cai D, Dai X
Journal of Cancer 2020;11(5):1162-1169
Journal of Cancer 2020;11(5):1162-1169
Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development.
Ge W, Tan SJ, Wang SH, Li L, Sun XF, Shen W, Wang X
Theranostics 2020;10(17):7581-7598
Theranostics 2020;10(17):7581-7598
The F-box protein FBXO11 restrains hepatocellular carcinoma stemness via promotion of ubiquitin-mediated degradation of Snail.
Shao L, Zhang X, Yao Q
FEBS open bio 2020 Sep;10(9):1810-1820
FEBS open bio 2020 Sep;10(9):1810-1820
SULT4A1 Modulates Synaptic Development and Function by Promoting the Formation of PSD-95/NMDAR Complex.
Culotta L, Scalmani P, Vinci E, Terragni B, Sessa A, Broccoli V, Mantegazza M, Boeckers T, Verpelli C
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Sep 9;40(37):7013-7026
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Sep 9;40(37):7013-7026
Neural progenitor cell pyroptosis contributes to Zika virus-induced brain atrophy and represents a therapeutic target.
He Z, An S, Chen J, Zhang S, Tan C, Yu J, Ye H, Wu Y, Yuan J, Wu J, Zhu X, Li M
Proceedings of the National Academy of Sciences of the United States of America 2020 Sep 22;117(38):23869-23878
Proceedings of the National Academy of Sciences of the United States of America 2020 Sep 22;117(38):23869-23878
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Chen Y, Niu J, Li L, Li Z, Jiang J, Zhu M, Dong T, Zhang J, Shi C, Xu P, Lu Y, Jiang Y, Liu P, Chen W
Life sciences 2020 Oct 1;258:118158
Life sciences 2020 Oct 1;258:118158
Bufalin attenuates triple-negative breast cancer cell stemness by inhibiting the expression of SOX2/OCT4.
Chen F, Zhu L, Hu J, Jiang S, Liu H, Zheng J, Wang J, Wang F, Li Z
Oncology letters 2020 Nov;20(5):171
Oncology letters 2020 Nov;20(5):171
Nucleotide de novo synthesis increases breast cancer stemness and metastasis via cGMP-PKG-MAPK signaling pathway.
Lv Y, Wang X, Li X, Xu G, Bai Y, Wu J, Piao Y, Shi Y, Xiang R, Wang L
PLoS biology 2020 Nov;18(11):e3000872
PLoS biology 2020 Nov;18(11):e3000872
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
Xiang L, Huang X, Wang S, Ou H, Chen Z, Hu Z, Huang Y, Li X, Yuan Y, Yang D
Cancer science 2020 Nov;111(11):4102-4117
Cancer science 2020 Nov;111(11):4102-4117
The miRNA-149-5p/MyD88 axis is responsible for ursolic acid-mediated attenuation of the stemness and chemoresistance of non-small cell lung cancer cells.
Chen Q, Luo J, Wu C, Lu H, Cai S, Bao C, Liu D, Kong J
Environmental toxicology 2020 May;35(5):561-569
Environmental toxicology 2020 May;35(5):561-569
Bisphenol A and polychlorinated biphenyls enhance the cancer stem cell properties of human ovarian cancer cells by activating the WNT signaling pathway.
Guo Y, Li B, Yan X, Shen X, Ma J, Liu S, Zhang D
Chemosphere 2020 May;246:125775
Chemosphere 2020 May;246:125775
Generation of a human induced pluripotent stem cell line (SDUBMSi001-A) from a hereditary spastic paraplegia patient carrying kif1a c.773C>T missense mutation.
Xiaojing W, Yanyan M, Ruonan D, Xiaolin L, Haiyan Z, Jian M, Yi L, Wenjie S, Qiji L
Stem cell research 2020 Mar;43:101727
Stem cell research 2020 Mar;43:101727
Generation of patient-specific pluripotent induced stem cell line SDUBMSI002-A from a patient with X-linked mental retardation syndrome.
Liu X, Yang X, Li Y, Wang X, Ma J, Jiang W, Liu Y, Sun W, Gong Y
Stem cell research 2020 Mar;43:101724
Stem cell research 2020 Mar;43:101724
LncRNA-cCSC1 modulates cancer stem cell properties in colorectal cancer via activation of the Hedgehog signaling pathway.
Zhou H, Xiong Y, Peng L, Wang R, Zhang H, Fu Z
Journal of cellular biochemistry 2020 Mar;121(3):2510-2524
Journal of cellular biochemistry 2020 Mar;121(3):2510-2524
Inhibition of PIM1 attenuates the stem cell-like traits of breast cancer cells by promoting RUNX3 nuclear retention.
Liu H, Chen C, Ma D, Li Y, Yin Q, Li Q, Xiang C
Journal of cellular and molecular medicine 2020 Jun;24(11):6308-6323
Journal of cellular and molecular medicine 2020 Jun;24(11):6308-6323
MCF7 Spheroid Development: New Insight about Spatio/Temporal Arrangements of TNTs, Amyloid Fibrils, Cell Connections, and Cellular Bridges.
Pulze L, Congiu T, Brevini TAL, Grimaldi A, Tettamanti G, D'Antona P, Baranzini N, Acquati F, Ferraro F, de Eguileor M
International journal of molecular sciences 2020 Jul 29;21(15)
International journal of molecular sciences 2020 Jul 29;21(15)
Zinc Promotes Patient-Derived Induced Pluripotent Stem Cell Neural Differentiation via ERK-STAT Signaling.
Yang M, Bao D, Shi A, Yuan H, Wang J, He W, Tong X, Qin H
Stem cells and development 2020 Jul 1;29(13):863-875
Stem cells and development 2020 Jul 1;29(13):863-875
Generation of an iPSC line (HUSTi002-A) from fibroblasts of a patient with Sertoli cell-only syndrome carrying c.731_732delAT in PIWIL2 gene.
Wang X, Xie S, Li Z, Ye Z, Gu X, Zhou L, Li H
Stem cell research 2020 Jan;42:101703
Stem cell research 2020 Jan;42:101703
Chlorogenic acid inhibits esophageal squamous cell carcinoma growth in vitro and in vivo by downregulating the expression of BMI1 and SOX2.
Zhan Y, Li R, Feng C, Li X, Huang S, Wang L, Liu Z, Jiang J, Han Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109602
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109602
Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer.
Apaya MK, Hsiao PW, Yang YC, Shyur LF
Cancers 2020 Jan 13;12(1)
Cancers 2020 Jan 13;12(1)
Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells.
Sun D, Yang L, Cao H, Shen ZY, Song HL
Cell biology international 2020 Feb;44(2):549-559
Cell biology international 2020 Feb;44(2):549-559
CMIP promotes Herceptin resistance of HER2 positive gastric cancer cells.
Xiang R, Han X, Ding K, Wu Z
Pathology, research and practice 2020 Feb;216(2):152776
Pathology, research and practice 2020 Feb;216(2):152776
MicroRNA‑487b‑3p inhibits osteosarcoma chemoresistance and metastasis by targeting ALDH1A3.
Cheng M, Duan PG, Gao ZZ, Dai M
Oncology reports 2020 Dec;44(6):2691-2700
Oncology reports 2020 Dec;44(6):2691-2700
Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.
Zhao Q, Sun P, Qin S, Liu J
Environmental toxicology 2020 Dec;35(12):1299-1307
Environmental toxicology 2020 Dec;35(12):1299-1307
miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis.
Shi DM, Shi XL, Xing KL, Zhou HX, Lu LL, Wu WZ
Cellular signalling 2020 Aug;72:109650
Cellular signalling 2020 Aug;72:109650
LIPH promotes metastasis by enriching stem-like cells in triple-negative breast cancer.
Zhang Y, Zhu X, Qiao X, Gu X, Xue J, Han Y, Sun L, Cui M, Liu C
Journal of cellular and molecular medicine 2020 Aug;24(16):9125-9134
Journal of cellular and molecular medicine 2020 Aug;24(16):9125-9134
The Effects of Daxx Knockout on Pluripotency and Differentiation of Mouse Induced Pluripotent Stem Cells.
Liu H, Liu Z, Gao M, Hu X, Sun R, Shen X, Liu F, Shen J, Shan Z, Lei L
Cellular reprogramming 2020 Apr;22(2):90-98
Cellular reprogramming 2020 Apr;22(2):90-98
WIP1 promotes cancer stem cell properties by inhibiting p38 MAPK in NSCLC.
Deng K, Liu L, Tan X, Zhang Z, Li J, Ou Y, Wang X, Yang S, Xiang R, Sun P
Signal transduction and targeted therapy 2020 Apr 15;5(1):36
Signal transduction and targeted therapy 2020 Apr 15;5(1):36
Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat.
Wang S, Li F, Liu J, Zhang Y, Zheng Y, Ge W, Qu L, Wang X
Cells 2020 Apr 14;9(4)
Cells 2020 Apr 14;9(4)
Microenvironment Can Induce Development of Auditory Progenitor Cells from Human Gingival Mesenchymal Stem Cells.
Pouraghaei S, Moztarzadeh F, Chen C, Ansari S, Moshaverinia A
ACS biomaterials science & engineering 2020 Apr 13;6(4):2263-2273
ACS biomaterials science & engineering 2020 Apr 13;6(4):2263-2273
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, Cui Y, Tian Y, An T, Zhang J, Li Z, Yang X
Theranostics 2019;9(5):1453-1473
Theranostics 2019;9(5):1453-1473
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, Wu J, Zhong C, Li X, Meng Z
Theranostics 2019;9(16):4827-4840
Theranostics 2019;9(16):4827-4840
COL4A2 in the tissue-specific extracellular matrix plays important role on osteogenic differentiation of periodontal ligament stem cells.
Wen Y, Yang H, Wu J, Wang A, Chen X, Hu S, Zhang Y, Bai D, Jin Z
Theranostics 2019;9(15):4265-4286
Theranostics 2019;9(15):4265-4286
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Kampo S, Ahmmed B, Zhou T, Owusu L, Anabah TW, Doudou NR, Kuugbee ED, Cui Y, Lu Z, Yan Q, Wen QP
Frontiers in oncology 2019;9:21
Frontiers in oncology 2019;9:21
Limbal niche cells can reduce the angiogenic potential of cultivated oral mucosal epithelial cells.
Duan CY, Xie HT, Zhao XY, Xu WH, Zhang MC
Cellular & molecular biology letters 2019;24:3
Cellular & molecular biology letters 2019;24:3
Modeling Retinitis Pigmentosa: Retinal Organoids Generated From the iPSCs of a Patient With the USH2A Mutation Show Early Developmental Abnormalities.
Guo Y, Wang P, Ma JH, Cui Z, Yu Q, Liu S, Xue Y, Zhu D, Cao J, Li Z, Tang S, Chen J
Frontiers in cellular neuroscience 2019;13:361
Frontiers in cellular neuroscience 2019;13:361
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer.
Zhao H, Wu S, Li H, Duan Q, Zhang Z, Shen Q, Wang C, Yin T
Molecular therapy oncolytics 2019 Sep 27;14:299-312
Molecular therapy oncolytics 2019 Sep 27;14:299-312
Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma.
Li C, Zheng H, Hou W, Bao H, Xiong J, Che W, Gu Y, Sun H, Liang P
Cell death & disease 2019 Sep 26;10(10):717
Cell death & disease 2019 Sep 26;10(10):717
Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway.
Liu Y, Jiang Q, Liu X, Lin X, Tang Z, Liu C, Zhou J, Zhao M, Li X, Cheng Z, Li L, Xie Y, Liu Z, Fang W
EBioMedicine 2019 Oct;48:386-404
EBioMedicine 2019 Oct;48:386-404
Six1 is negatively correlated with poor prognosis and reduces 5-fluorouracil sensitivity via attenuating the stemness of hepatocellular carcinoma cells.
Chen K, Wei H, Pan J, Chen Z, Pan D, Gao T, Huang J, Huang M, Ou M, Zhong W
European journal of pharmacology 2019 Oct 15;861:172599
European journal of pharmacology 2019 Oct 15;861:172599
N-acetylcysteine alleviated paraquat-induced mitochondrial fragmentation and autophagy in primary murine neural progenitor cells.
Xiong G, Zhao L, Yan M, Wang X, Zhou Z, Chang X
Journal of applied toxicology : JAT 2019 Nov;39(11):1557-1567
Journal of applied toxicology : JAT 2019 Nov;39(11):1557-1567
Pre-metastatic niche triggers SDF-1/CXCR4 axis and promotes organ colonisation by hepatocellular circulating tumour cells via downregulation of Prrx1.
Tang Y, Lu Y, Chen Y, Luo L, Cai L, Peng B, Huang W, Liao H, Zhao L, Pan M
Journal of experimental & clinical cancer research : CR 2019 Nov 21;38(1):473
Journal of experimental & clinical cancer research : CR 2019 Nov 21;38(1):473
A small molecule Hedgehog agonist HhAg1.5 mediated reprogramming breaks the quiescence of noninjured liver stem cells for rescuing liver failure.
Mitra A, Yan J, Zhang L, Li S
Translational research : the journal of laboratory and clinical medicine 2019 Mar;205:44-50
Translational research : the journal of laboratory and clinical medicine 2019 Mar;205:44-50
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Li Z, Chen Y, An T, Liu P, Zhu J, Yang H, Zhang W, Dong T, Jiang J, Zhang Y, Jiang M, Yang X
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.
Zhu R, Gires O, Zhu L, Liu J, Li J, Yang H, Ju G, Huang J, Ge W, Chen Y, Lu Z, Wang H
Nature communications 2019 Jun 28;10(1):2863
Nature communications 2019 Jun 28;10(1):2863
Chondroitin sulfate proteoglycan represses neural stem/progenitor cells migration via PTPσ/α-actinin4 signaling pathway.
Zhong J, Lan C, Zhang C, Yang Y, Chen WX, Zhang KY, Zhao HL, Fang XY, Li HH, Tan L, Wang P, Ge HF, Hu R, Feng H
Journal of cellular biochemistry 2019 Jul;120(7):11008-11021
Journal of cellular biochemistry 2019 Jul;120(7):11008-11021
In vivo tracking on longer retention of transplanted myocardin gene-modified adipose-derived stem cells to improve erectile dysfunction in diabetic rats.
Zhang HB, Chen FZ, He SH, Liang YB, Wang ZQ, Wang L, Chen ZR, Ding W, Zhao SC, Wei AY
Stem cell research & therapy 2019 Jul 16;10(1):208
Stem cell research & therapy 2019 Jul 16;10(1):208
G protein-coupled estrogen receptor 1 negatively regulates the proliferation of mouse-derived neural stem/progenitor cells via extracellular signal-regulated kinase pathway.
Zhong J, Ge HF, Zhang C, Chen JY, Li HH, Fang XY, Tan L, Liu X, Jia ZC, Feng H, Hu R
Brain research 2019 Jul 1;1714:158-165
Brain research 2019 Jul 1;1714:158-165
Downregulation of DAPK1 promotes the stemness of cancer stem cells and EMT process by activating ZEB1 in colorectal cancer.
Yuan W, Ji J, Shu Y, Chen J, Liu S, Wu L, Zhou Z, Liu Z, Tang Q, Zhang X, Shu X
Journal of molecular medicine (Berlin, Germany) 2019 Jan;97(1):89-102
Journal of molecular medicine (Berlin, Germany) 2019 Jan;97(1):89-102
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
Li B, Cao Y, Meng G, Qian L, Xu T, Yan C, Luo O, Wang S, Wei J, Ding Y, Yu D
EBioMedicine 2019 Jan;39:239-254
EBioMedicine 2019 Jan;39:239-254
Bruceine D inhibits tumor growth and stem cell-like traits of osteosarcoma through inhibition of STAT3 signaling pathway.
Wang S, Hu H, Zhong B, Shi D, Qing X, Cheng C, Deng X, Zhang Z, Shao Z
Cancer medicine 2019 Dec;8(17):7345-7358
Cancer medicine 2019 Dec;8(17):7345-7358
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Liu Q, Guan Y, Li Z, Wang Y, Liu Y, Cui R, Wang Y
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Targeting Hyaluronan Interactions for Glioblastoma Stem Cell Therapy.
Hartheimer JS, Park S, Rao SS, Kim Y
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2019 Apr;12(1):47-56
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2019 Apr;12(1):47-56
Stabilized Peptide HDAC Inhibitors Derived from HDAC1 Substrate H3K56 for the Treatment of Cancer Stem-Like Cells In Vivo.
Wang D, Li W, Zhao R, Chen L, Liu N, Tian Y, Zhao H, Xie M, Lu F, Fang Q, Liang W, Yin F, Li Z
Cancer research 2019 Apr 15;79(8):1769-1783
Cancer research 2019 Apr 15;79(8):1769-1783
Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation.
Ai L, Mu S, Sun C, Fan F, Yan H, Qin Y, Cui G, Wang Y, Guo T, Mei H, Wang H, Hu Y
Molecular cancer 2019 Apr 13;18(1):88
Molecular cancer 2019 Apr 13;18(1):88
Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma.
Zeng X, Wang Q, Tan X, Jia L, Li Y, Hu M, Zhang Z, Bai X, Zhu Y, Yang X
Journal of nanobiotechnology 2019 Apr 1;17(1):47
Journal of nanobiotechnology 2019 Apr 1;17(1):47
Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19.
Ren J, Ding L, Zhang D, Shi G, Xu Q, Shen S, Wang Y, Wang T, Hou Y
Theranostics 2018;8(14):3932-3948
Theranostics 2018;8(14):3932-3948
The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway.
Sun Z, Zhu M, Lv P, Cheng L, Wang Q, Tian P, Yan Z, Wen B
Stem cell reports 2018 Sep 11;11(3):741-755
Stem cell reports 2018 Sep 11;11(3):741-755
FBXW7 suppresses epithelial-mesenchymal transition and chemo-resistance of non-small-cell lung cancer cells by targeting snai1 for ubiquitin-dependent degradation.
Xiao G, Li Y, Wang M, Li X, Qin S, Sun X, Liang R, Zhang B, Du N, Xu C, Ren H, Liu D
Cell proliferation 2018 Oct;51(5):e12473
Cell proliferation 2018 Oct;51(5):e12473
Expression patterns of Rbm24 in lens, nasal epithelium, and inner ear during mouse embryonic development.
Grifone R, Saquet A, Xu Z, Shi DL
Developmental dynamics : an official publication of the American Association of Anatomists 2018 Oct;247(10):1160-1169
Developmental dynamics : an official publication of the American Association of Anatomists 2018 Oct;247(10):1160-1169
Knockdown of Sox2 Inhibits OS Cells Invasion and Migration via Modulating Wnt/β-Catenin Signaling Pathway.
Tang L, Wang D, Gu D
Pathology oncology research : POR 2018 Oct;24(4):907-913
Pathology oncology research : POR 2018 Oct;24(4):907-913
Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury.
Liu Y, Cao W, Kong X, Li J, Chen X, Ge Y, Zhong W, Fang S
Molecular medicine reports 2018 Nov;18(5):4219-4228
Molecular medicine reports 2018 Nov;18(5):4219-4228
TRPV4 Activation Contributes Functional Recovery from Ischemic Stroke via Angiogenesis and Neurogenesis.
Chen CK, Hsu PY, Wang TM, Miao ZF, Lin RT, Juo SH
Molecular neurobiology 2018 May;55(5):4127-4135
Molecular neurobiology 2018 May;55(5):4127-4135
Generation of an iPS cell line via a non-integrative method using urine-derived cells from a patient with USH2A-associated retinitis pigmentosa.
Guo Y, Zeng Q, Liu S, Yu Q, Wang P, Ma H, Shi S, Yan X, Cui Z, Xie M, Xue Y, Zha Q, Li Z, Zhang J, Tang S, Chen J
Stem cell research 2018 May;29:139-142
Stem cell research 2018 May;29:139-142
Directing Induced Pluripotent Stem Cell Derived Neural Stem Cell Fate with a Three-Dimensional Biomimetic Hydrogel for Spinal Cord Injury Repair.
Fan L, Liu C, Chen X, Zou Y, Zhou Z, Lin C, Tan G, Zhou L, Ning C, Wang Q
ACS applied materials & interfaces 2018 May 30;10(21):17742-17755
ACS applied materials & interfaces 2018 May 30;10(21):17742-17755
The ubiquitin ligase SCF(FBXW7α) promotes GATA3 degradation.
Song N, Cao C, Tang Y, Bi L, Jiang Y, Zhou Y, Song X, Liu L, Ge W
Journal of cellular physiology 2018 Mar;233(3):2366-2377
Journal of cellular physiology 2018 Mar;233(3):2366-2377
Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
Jia W, Jiang X, Liu W, Wang L, Zhu B, Zhu H, Liu X, Zhong M, Xie D, Huang W, Jia W, Li S, Liu X, Zuo X, Cheng D, Dai J, Ren C
International journal of oncology 2018 Jun;52(6):1787-1800
International journal of oncology 2018 Jun;52(6):1787-1800
The three branches of the unfolded protein response exhibit differential significance in breast cancer growth and stemness.
Li C, Fan Q, Quan H, Nie M, Luo Y, Wang L
Experimental cell research 2018 Jun 15;367(2):170-185
Experimental cell research 2018 Jun 15;367(2):170-185
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Song L, Chen X, Wang P, Gao S, Qu C, Liu L
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Wang J, Tian L, Khan MN, Zhang L, Chen Q, Zhao Y, Yan Q, Fu L, Liu J
Cancer letters 2018 Feb 28;415:73-85
Cancer letters 2018 Feb 28;415:73-85
[Impact of Cystic Fibrosis Transmembrane Conductance Regulator on Malignant Properties of KRAS Mutant Lung Adenocarcinoma A549 Cells].
Li H, Wang Y, Yang J, Liu X, Shi J
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2018 Feb 20;21(2):89-98
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2018 Feb 20;21(2):89-98
Neuralized1a regulates asymmetric division in mouse Lewis lung carcinoma cells.
Kong L, Li J, Liu Y, Sun Z, Zhou S, Tang J, Ye T, Wang J, Rosie Xing H
Life sciences 2018 Aug 1;206:70-76
Life sciences 2018 Aug 1;206:70-76
Characterization of 3D embryonic C57BL/6 and A/J mouse midbrain micromass in vitro culture systems for developmental neurotoxicity testing.
Park JJ, Weldon BA, Hong S, Workman T, Griffith WC, Park JH, Faustman EM
Toxicology in vitro : an international journal published in association with BIBRA 2018 Apr;48:33-44
Toxicology in vitro : an international journal published in association with BIBRA 2018 Apr;48:33-44
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Yang HF, Yu M, Jin HD, Yao JQ, Lu ZL, Yabasin IB, Yan Q, Wen QP
Frontiers in physiology 2017;8:510
Frontiers in physiology 2017;8:510
miR34a/GOLPH3 Axis abrogates Urothelial Bladder Cancer Chemoresistance via Reduced Cancer Stemness.
Zhang Q, Zhuang J, Deng Y, Yang L, Cao W, Chen W, Lin T, Lv X, Yu H, Xue Y, Guo H
Theranostics 2017;7(19):4777-4790
Theranostics 2017;7(19):4777-4790
Soluble expression of recomb inant cMyc, Klf4, Oct4, and Sox2 proteins in bacteria and transduction into living cells.
Liu GD, Zhou SF, Ding XC, Fang CL, Mi SY, Gao XC, Han Q
International journal of ophthalmology 2017;10(4):560-566
International journal of ophthalmology 2017;10(4):560-566
Bufalin reverses acquired drug resistance by inhibiting stemness in colorectal cancer cells.
Sun J, Xu K, Qiu Y, Gao H, Xu J, Tang Q, Yin P
Oncology reports 2017 Sep;38(3):1420-1430
Oncology reports 2017 Sep;38(3):1420-1430
Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice.
Vicidomini C, Ponzoni L, Lim D, Schmeisser MJ, Reim D, Morello N, Orellana D, Tozzi A, Durante V, Scalmani P, Mantegazza M, Genazzani AA, Giustetto M, Sala M, Calabresi P, Boeckers TM, Sala C, Verpelli C
Molecular psychiatry 2017 May;22(5):689-702
Molecular psychiatry 2017 May;22(5):689-702
Silencing of Btbd7 Inhibited Epithelial-Mesenchymal Transition and Chemoresistance in CD133(+) Lung Carcinoma A549 Cells.
Fang LZ, Zhang JQ, Liu L, Fu WP, Shu JK, Feng JG, Liang X
Oncology research 2017 May 24;25(5):819-829
Oncology research 2017 May 24;25(5):819-829
Overexpression of PER3 Inhibits Self-Renewal Capability and Chemoresistance of Colorectal Cancer Stem-Like Cells via Inhibition of Notch and β-Catenin Signaling.
Zhang F, Sun H, Zhang S, Yang X, Zhang G, Su T
Oncology research 2017 May 24;25(5):709-719
Oncology research 2017 May 24;25(5):709-719
Generation and characterization of induced pluripotent stem cells from guinea pig fetal fibroblasts.
Wu Y, Li O, He C, Li Y, Li M, Liu XL, Wang Y, He Y
Molecular medicine reports 2017 Jun;15(6):3690-3698
Molecular medicine reports 2017 Jun;15(6):3690-3698
The X-Linked Intellectual Disability Protein IL1RAPL1 Regulates Dendrite Complexity.
Montani C, Ramos-Brossier M, Ponzoni L, Gritti L, Cwetsch AW, Braida D, Saillour Y, Terragni B, Mantegazza M, Sala M, Verpelli C, Billuart P, Sala C
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Jul 12;37(28):6606-6627
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Jul 12;37(28):6606-6627
Transcriptional suppression of microRNA-27a contributes to laryngeal cancer differentiation via GSK-3β-involved Wnt/β-catenin pathway.
Chen S, Sun YY, Zhang ZX, Li YH, Xu ZM, Fu WN
Oncotarget 2017 Feb 28;8(9):14708-14718
Oncotarget 2017 Feb 28;8(9):14708-14718
Injury Induces Endogenous Reprogramming and Dedifferentiation of Neuronal Progenitors to Multipotency.
Lin B, Coleman JH, Peterson JN, Zunitch MJ, Jang W, Herrick DB, Schwob JE
Cell stem cell 2017 Dec 7;21(6):761-774.e5
Cell stem cell 2017 Dec 7;21(6):761-774.e5
Expression of Stem Cell Markers and Dopamine D2 Receptors in Human and Rat Prolactinomas.
Gao Z, Cai L, Lu J, Wang C, Li Q, Chen J, Song X, Chen X, Zhang L, Zheng W, Su Z
Medical science monitor : international medical journal of experimental and clinical research 2017 Apr 15;23:1827-1833
Medical science monitor : international medical journal of experimental and clinical research 2017 Apr 15;23:1827-1833
Sox2 and Pax6 Play Counteracting Roles in Regulating Neurogenesis within the Murine Olfactory Epithelium.
Packard AI, Lin B, Schwob JE
PloS one 2016;11(5):e0155167
PloS one 2016;11(5):e0155167
miR-612 suppresses stem cell-like property of hepatocellular carcinoma cells by modulating Sp1/Nanog signaling.
Liu Y, Liu DL, Dong LL, Wen D, Shi DM, Zhou J, Fan J, Wu WZ
Cell death & disease 2016 Sep 29;7(9):e2377
Cell death & disease 2016 Sep 29;7(9):e2377
Differential epigenetic effects of chlorpyrifos and arsenic in proliferating and differentiating human neural progenitor cells.
Kim HY, Wegner SH, Van Ness KP, Park JJ, Pacheco SE, Workman T, Hong S, Griffith W, Faustman EM
Reproductive toxicology (Elmsford, N.Y.) 2016 Oct;65:212-223
Reproductive toxicology (Elmsford, N.Y.) 2016 Oct;65:212-223
Persistent Cytomegalovirus Infection in Amniotic Membranes of the Human Placenta.
Tabata T, Petitt M, Fang-Hoover J, Zydek M, Pereira L
The American journal of pathology 2016 Nov;186(11):2970-2986
The American journal of pathology 2016 Nov;186(11):2970-2986
Combinatorial enzymatic digestion with thermolysin and collagenase type I improved the isolation and culture effects of hair cell progenitors from rat cochleae.
Song YL, Tian KY, Mi WJ, Han P, Ding ZJ, Qiu Y, Chen FQ, Qiu JJ
In vitro cellular & developmental biology. Animal 2016 May;52(5):537-44
In vitro cellular & developmental biology. Animal 2016 May;52(5):537-44
ROCK inhibitor Y27632 promotes proliferation and diminishes apoptosis of marmoset induced pluripotent stem cells by suppressing expression and activity of caspase 3.
Wu Y, Shu J, He C, Li M, Wang Y, Ou W, He Y
Theriogenology 2016 Jan 15;85(2):302-14
Theriogenology 2016 Jan 15;85(2):302-14
Hyperglycemic Stress Impairs the Stemness Capacity of Kidney Stem Cells in Rats.
Yang G, Jia Y, Li C, Cheng Q, Yue W, Pei X
PloS one 2015;10(10):e0139607
PloS one 2015;10(10):e0139607
The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signaling.
Wang Y, He L, Du Y, Zhu P, Huang G, Luo J, Yan X, Ye B, Li C, Xia P, Zhang G, Tian Y, Chen R, Fan Z
Cell stem cell 2015 Apr 2;16(4):413-25
Cell stem cell 2015 Apr 2;16(4):413-25
Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells.
Tao H, Li H, Su Y, Feng D, Wang X, Zhang C, Ma H, Hu Q
Molecular and cellular biochemistry 2014 Sep;394(1-2):23-30
Molecular and cellular biochemistry 2014 Sep;394(1-2):23-30
Low concentration of serum helps to maintain the characteristics of NSCs/NPCs on alkali-treated PHBHHx film in vitro.
Lu HX, Yang ZQ, Jiao Q, Wang YY, Wang L, Yang PB, Chen XL, Zhang PB, Wang P, Chen MX, Lu XY, Liu Y
Neurological research 2014 Mar;36(3):207-14
Neurological research 2014 Mar;36(3):207-14
Correlation of ALDH1, CD44, OCT4 and SOX2 in tongue squamous cell carcinoma and their association with disease progression and prognosis.
Huang CF, Xu XR, Wu TF, Sun ZJ, Zhang WF
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2014 Aug;43(7):492-8
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Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle.
Piazzon N, Schlotter F, Lefebvre S, Dodré M, Méreau A, Soret J, Besse A, Barkats M, Bordonné R, Branlant C, Massenet S
Nucleic acids research 2013 Jan;41(2):1255-72
Nucleic acids research 2013 Jan;41(2):1255-72
In vitro neurogenesis from neural progenitor cells isolated from the hippocampus region of the brain of adult rats exposed to ethanol during early development through their alcohol-drinking mothers.
Singh AK, Gupta S, Jiang Y, Younus M, Ramzan M
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Alcohol and alcoholism (Oxford, Oxfordshire) 2009 Mar-Apr;44(2):185-98
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Confocal immunofluorescent analysis of human embronic stem cells with 11064-1-AP at dilution of 1:50. The PE shows staining with 11064-1-AP/PE. The DAPI shows nuclear staining by DAPI.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 11064-1-AP(SOX2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue