SOX2

gene product
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
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Antibodies

 

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Antibodypedia Validation Initiative

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1545 antibodies from 46 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
21 antibodies
GeneTex
13 antibodies
antibodies-online
585 antibodies
Novus Biologicals
117 antibodies
R&D Systems
22 antibodies
Abnova Corporation
18 antibodies