Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations [0]
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- Product number
- 630901 - Provider product page
- Provider
- BioLegend
- Product name
- Purified anti-SOX2 (COOH terminus)
- Antibody type
- Polyclonal
- Antigen
- Peptide-KLH (C-terminal)
- Description
- This rabbit polyclonal antibody recognizes human SOX2 also known as SRY (sex determining region Y)-box 2 and ANOP3. SOX2 is a nucleus protein, predicted molecular weight 34 kD. SOX2 belongs to the SOX (SRY-box containing gene) gene family which encodes a group of transcription factors defined by the conserved high motility group (HMG) DNA-binding domain. They are involved in the regulation of embryonic development and in the determination of cell fate. Defects in SOX2 are a cause of true or primary anophthalmos, also called anophthalmia or ANOP3. Anophthalmos is a developmental defect characterized by complete absence of the eyes (rare) or by the presence of vestigial eyes. The poly6309 antibody has been shown to be useful for Western blotting.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 50 µl
- Storage
- Upon receipt, store frozen at -20° C.
Submitted references Generation of genetically modified rats from embryonic stem cells.
Kawamata M, Ochiya T
Proceedings of the National Academy of Sciences of the United States of America 2010 Aug 10;107(32):14223-8
Proceedings of the National Academy of Sciences of the United States of America 2010 Aug 10;107(32):14223-8
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