Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [2]
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- Product number
- ABIN258037 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-100), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Sheep
- Host
- Rabbit
- Epitope
- N-Term, AA 1-100
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Sox2 expression in Schwann cells inhibits myelination in vivo and induces influx of macrophages to the nerve.
Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment.
SIRT1-mediated transcriptional regulation of SOX2 is important for self-renewal of liver cancer stem cells.
Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells.
Neural stem cells from mouse strain Thy1 YFP-16 are a valuable tool to monitor and evaluate neuronal differentiation and morphology.
High-efficiency cellular reprogramming with microfluidics.
Predicting the molecular role of MEIS1 in esophageal squamous cell carcinoma.
Plasminogen activator inhibitor-1 as regulator of tumor-initiating cell properties in head and neck cancers.
Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype.
Pluripotent state induction in mouse embryonic fibroblast using mRNAs of reprogramming factors.
Efficient germ-line transmission obtained with transgene-free induced pluripotent stem cells.
Beneficial actions of the anti-inflammatory dimethyl fumarate in glioblastomas.
Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Connexin 43 reverses malignant phenotypes of glioma stem cells by modulating E-cadherin.
Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2.
Roberts SL, Dun XP, Doddrell RDS, Mindos T, Drake LK, Onaitis MW, Florio F, Quattrini A, Lloyd AC, D'Antonio M, Parkinson DB
Development (Cambridge, England) 2017 Sep 1;144(17):3114-3125
Development (Cambridge, England) 2017 Sep 1;144(17):3114-3125
Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment.
Lu H, Chen I, Shimoda LA, Park Y, Zhang C, Tran L, Zhang H, Semenza GL
Cell reports 2017 Feb 21;18(8):1946-1957
Cell reports 2017 Feb 21;18(8):1946-1957
SIRT1-mediated transcriptional regulation of SOX2 is important for self-renewal of liver cancer stem cells.
Liu L, Liu C, Zhang Q, Shen J, Zhang H, Shan J, Duan G, Guo D, Chen X, Cheng J, Xu Y, Yang Z, Yao C, Lai M, Qian C
Hepatology (Baltimore, Md.) 2016 Sep;64(3):814-27
Hepatology (Baltimore, Md.) 2016 Sep;64(3):814-27
Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells.
Zhang C, Zhi WI, Lu H, Samanta D, Chen I, Gabrielson E, Semenza GL
Oncotarget 2016 Oct 4;7(40):64527-64542
Oncotarget 2016 Oct 4;7(40):64527-64542
Neural stem cells from mouse strain Thy1 YFP-16 are a valuable tool to monitor and evaluate neuronal differentiation and morphology.
Alić I, Kosi N, Kapuralin K, Gorup D, Gajović S, Pochet R, Mitrečić D
Neuroscience letters 2016 Nov 10;634:32-41
Neuroscience letters 2016 Nov 10;634:32-41
High-efficiency cellular reprogramming with microfluidics.
Luni C, Giulitti S, Serena E, Ferrari L, Zambon A, Gagliano O, Giobbe GG, Michielin F, Knöbel S, Bosio A, Elvassore N
Nature methods 2016 May;13(5):446-52
Nature methods 2016 May;13(5):446-52
Predicting the molecular role of MEIS1 in esophageal squamous cell carcinoma.
Rad A, Farshchian M, Forghanifard MM, Matin MM, Bahrami AR, Geerts D, A'rabi A, Memar B, Abbaszadegan MR
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Feb;37(2):1715-25
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Feb;37(2):1715-25
Plasminogen activator inhibitor-1 as regulator of tumor-initiating cell properties in head and neck cancers.
Lee YC, Yu CC, Lan C, Lee CH, Lee HT, Kuo YL, Wang PH, Chang WW
Head & neck 2016 Apr;38 Suppl 1:E895-904
Head & neck 2016 Apr;38 Suppl 1:E895-904
Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype.
Lu H, Samanta D, Xiang L, Zhang H, Hu H, Chen I, Bullen JW, Semenza GL
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 18;112(33):E4600-9
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 18;112(33):E4600-9
Pluripotent state induction in mouse embryonic fibroblast using mRNAs of reprogramming factors.
El-Sayed AK, Zhang Z, Zhang L, Liu Z, Abbott LC, Zhang Y, Li B
International journal of molecular sciences 2014 Nov 27;15(12):21840-64
International journal of molecular sciences 2014 Nov 27;15(12):21840-64
Efficient germ-line transmission obtained with transgene-free induced pluripotent stem cells.
Wu S, Wu Y, Zhang X, Capecchi MR
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 22;111(29):10678-83
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 22;111(29):10678-83
Beneficial actions of the anti-inflammatory dimethyl fumarate in glioblastomas.
Ghods AJ, Glick R, Braun D, Feinstein D
Surgical neurology international 2013;4:160
Surgical neurology international 2013;4:160
Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan T, Stein S, Qi J, Wende H, Garratt AN, Nave KA, Birchmeier C, Birchmeier W
Proceedings of the National Academy of Sciences of the United States of America 2013 Nov 5;110(45):18174-9
Proceedings of the National Academy of Sciences of the United States of America 2013 Nov 5;110(45):18174-9
Connexin 43 reverses malignant phenotypes of glioma stem cells by modulating E-cadherin.
Yu SC, Xiao HL, Jiang XF, Wang QL, Li Y, Yang XJ, Ping YF, Duan JJ, Jiang JY, Ye XZ, Xu SL, Xin YH, Yao XH, Chen JH, Chu WH, Sun W, Wang B, Wang JM, Zhang X, Bian XW
Stem cells (Dayton, Ohio) 2012 Feb;30(2):108-20
Stem cells (Dayton, Ohio) 2012 Feb;30(2):108-20
Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2.
Domyan ET, Ferretti E, Throckmorton K, Mishina Y, Nicolis SK, Sun X
Development (Cambridge, England) 2011 Mar;138(5):971-81
Development (Cambridge, England) 2011 Mar;138(5):971-81
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Supportive validation
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- IHC
Supportive validation
- Submitted by
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- FACS
- Submitted by
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- Main image
- Experimental details
- FACS