Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN2839124 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 89-119, N-Term
- Antibody clone number
- RB14026
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references MicroRNA-124 and -137 cooperativity controls caspase-3 activity through BCL2L13 in hippocampal neural stem cells.
Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation.
Identification of novel domains within Sox-2 and Sox-11 involved in autoinhibition of DNA binding and partnership specificity.
Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers.
Mutations in SOX2 cause anophthalmia.
Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families.
Pairing SOX off: with partners in the regulation of embryonic development.
Schouten M, Fratantoni SA, Hubens CJ, Piersma SR, Pham TV, Bielefeld P, Voskuyl RA, Lucassen PJ, Jimenez CR, Fitzsimons CP
Scientific reports 2015 Jul 24;5:12448
Scientific reports 2015 Jul 24;5:12448
Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation.
Su YC, Qi X
Human molecular genetics 2013 Nov 15;22(22):4545-61
Human molecular genetics 2013 Nov 15;22(22):4545-61
Identification of novel domains within Sox-2 and Sox-11 involved in autoinhibition of DNA binding and partnership specificity.
Wiebe MS, Nowling TK, Rizzino A
The Journal of biological chemistry 2003 May 16;278(20):17901-11
The Journal of biological chemistry 2003 May 16;278(20):17901-11
Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers.
Reményi A, Lins K, Nissen LJ, Reinbold R, Schöler HR, Wilmanns M
Genes & development 2003 Aug 15;17(16):2048-59
Genes & development 2003 Aug 15;17(16):2048-59
Mutations in SOX2 cause anophthalmia.
Fantes J, Ragge NK, Lynch SA, McGill NI, Collin JR, Howard-Peebles PN, Hayward C, Vivian AJ, Williamson K, van Heyningen V, FitzPatrick DR
Nature genetics 2003 Apr;33(4):461-3
Nature genetics 2003 Apr;33(4):461-3
Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families.
Schepers GE, Teasdale RD, Koopman P
Developmental cell 2002 Aug;3(2):167-70
Developmental cell 2002 Aug;3(2):167-70
Pairing SOX off: with partners in the regulation of embryonic development.
Kamachi Y, Uchikawa M, Kondoh H
Trends in genetics : TIG 2000 Apr;16(4):182-7
Trends in genetics : TIG 2000 Apr;16(4):182-7
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC