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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN357437 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- This SOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97~126 amino selected from the N-terminal region of human SOX2.
- Description
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Reactivity
- Human, Mouse, Zebrafish
- Host
- Rabbit
- Epitope
- N-Term
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Identification of novel domains within Sox-2 and Sox-11 involved in autoinhibition of DNA binding and partnership specificity.
Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers.
Mutations in SOX2 cause anophthalmia.
Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families.
Pairing SOX off: with partners in the regulation of embryonic development.
Wiebe MS, Nowling TK, Rizzino A
The Journal of biological chemistry 2003 May 16;278(20):17901-11
The Journal of biological chemistry 2003 May 16;278(20):17901-11
Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers.
Reményi A, Lins K, Nissen LJ, Reinbold R, Schöler HR, Wilmanns M
Genes & development 2003 Aug 15;17(16):2048-59
Genes & development 2003 Aug 15;17(16):2048-59
Mutations in SOX2 cause anophthalmia.
Fantes J, Ragge NK, Lynch SA, McGill NI, Collin JR, Howard-Peebles PN, Hayward C, Vivian AJ, Williamson K, van Heyningen V, FitzPatrick DR
Nature genetics 2003 Apr;33(4):461-3
Nature genetics 2003 Apr;33(4):461-3
Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families.
Schepers GE, Teasdale RD, Koopman P
Developmental cell 2002 Aug;3(2):167-70
Developmental cell 2002 Aug;3(2):167-70
Pairing SOX off: with partners in the regulation of embryonic development.
Kamachi Y, Uchikawa M, Kondoh H
Trends in genetics : TIG 2000 Apr;16(4):182-7
Trends in genetics : TIG 2000 Apr;16(4):182-7
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