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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN501094 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant Human TWEAK.
- Description
- Peptide Affinity Chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies.
The apoptotic ligands TRAIL, TWEAK, and Fas ligand mediate monocyte death induced by autologous lupus T cells.
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor.
TWEAK induces angiogenesis and proliferation of endothelial cells.
TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis.
Chicheportiche Y, Chicheportiche R, Sizing I, Thompson J, Benjamin CB, Ambrose C, Dayer JM
Arthritis research 2002;4(2):126-33
Arthritis research 2002;4(2):126-33
The apoptotic ligands TRAIL, TWEAK, and Fas ligand mediate monocyte death induced by autologous lupus T cells.
Kaplan MJ, Lewis EE, Shelden EA, Somers E, Pavlic R, McCune WJ, Richardson BC
Journal of immunology (Baltimore, Md. : 1950) 2002 Nov 15;169(10):6020-9
Journal of immunology (Baltimore, Md. : 1950) 2002 Nov 15;169(10):6020-9
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor.
Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K
Cell 2001 Dec 28;107(7):881-91
Cell 2001 Dec 28;107(7):881-91
TWEAK induces angiogenesis and proliferation of endothelial cells.
Lynch CN, Wang YC, Lund JK, Chen YW, Leal JA, Wiley SR
The Journal of biological chemistry 1999 Mar 26;274(13):8455-9
The Journal of biological chemistry 1999 Mar 26;274(13):8455-9
TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis.
Chicheportiche Y, Bourdon PR, Xu H, Hsu YM, Scott H, Hession C, Garcia I, Browning JL
The Journal of biological chemistry 1997 Dec 19;272(51):32401-10
The Journal of biological chemistry 1997 Dec 19;272(51):32401-10
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of (A) 5 ng, (B) 25 ng and (C) 50 ng of recombinant TWEAK with AP30972PU-N at 1 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of TWEAK in human brain tissue with AP30972PU-N at 10 ?g/ml.
