RA0101

antibody from Oursmab

Targeting: CD3E

Western blot (Data presented on provider website)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0101

Provider

Oursmab

Product name

Dafsolimab (Biosimilar Reference Antibody) (CD3E)

Antibody type

Monoclonal

Description

Dafsolimab is a murine-derived IgG2b monoclonal antibody targeting the CD3 molecule. As an anti-CD3 antibody, its primary application has historically been in basic immunology research and as a crucial tool reagent in biomedical science. It is used to study T-cell activation, signal transduction, and in vitro functional assays. In clinical contexts, early murine anti-CD3 antibodies (like OKT3) were used as potent immunosuppressants to prevent organ transplant rejection, but their use was limited by the development of human anti-mouse antibodies (HAMA) and significant cytokine release syndrome. Dafsolimab likely represents this class of foundational research or early therapeutic tools.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.