RA0106

antibody from Oursmab

Targeting: CD3E

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0106

Provider

Oursmab

Product name

Teplizumab (Biosimilar Reference Antibody) (CD3E)

Antibody type

Monoclonal

Description

Teplizumab is a humanized monoclonal antibody targeting CD3, a component of the T-cell receptor complex. It binds to CD3 on T cells to modulate immune responses, primarily by inducing partial T-cell depletion and promoting regulatory T-cell function. It is approved for delaying the onset of stage 3 type 1 diabetes (T1D) in high-risk individuals, representing the first disease-modifying therapy for T1D prevention.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Teplizumab (Biosimilar Reference Antibody) (CD3E)-RA0106-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Teplizumab (Biosimilar Reference Antibody) (CD3E)-RA0106 in a linear range of 15.63¨C125 ng/mL.