NB100-64343

antibody from Novus Biologicals

Targeting: CFB BF, BFD, H2-Bf

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

NB100-64343

Provider

Novus Biologicals

Proper citation

Novus Cat#NB100-64343, RRID:AB_963435

Product name

Mouse Monoclonal Complement Factor B Antibody

Antibody type

Monoclonal

Description

Protein A purified. NB100-64343 recognizes the 30kDa Ba fragment of 90kDa human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kDa Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes. NB100-64343 inhibits the function of factor B and binds both nascent factor B and the Ba cleavage product. Removal of Sodium Azide is recommended prior to use in functional assays.

Reactivity

Human

Host

Mouse

Isotype

IgG

Vial size

0.05 mg

Concentration

1 mg/ml

Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.