CFB

gene product
BF, BFD, H2-Bf
This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008]
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833 antibodies from 36 providers.

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Antibody
Novus Biologicals
50 antibodies
Atlas Antibodies
3 antibodies
OriGene
16 antibodies
GeneTex
8 antibodies
Proteintech Group
2 antibodies
antibodies-online
253 antibodies
Biorbyt
21 antibodies
LifeSpan BioSciences, Inc.
193 antibodies
Acris Antibodies GmbH
15 antibodies
Affinity Biosciences
1 antibody
Invitrogen Antibodies
18 antibodies
R&D Systems
3 antibodies
Aviva Systems Biology
8 antibodies
NovoPro Bioscience Inc.
2 antibodies
Abnova Corporation
7 antibodies
HUABIO Research
1 antibody
Abgent
2 antibodies
NSJ Bioreagents
1 antibody
Santa Cruz Biotechnology
1 antibody
ProSci
2 antibodies
Bioworld Technology, Inc
1 antibody
Boster Biological Technology
2 antibodies
Sigma-Aldrich
2 antibodies
Creative Biolabs
79 antibodies
Creative Diagnostics
10 antibodies
MyBioSource
23 antibodies
Abbexa
15 antibodies
GenWay
4 antibodies
United States Biological
63 antibodies
Leading Biology
3 antibodies
Abbiotec
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
St John's Laboratory
1 antibody
RabMAbs
2 antibodies
RayBiotech, Inc.
1 antibody