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Immunohistochemistry
RadioimmunoassayAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Immunohistochemistry [1]
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- Product number
- NB600-1506 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB600-1506, RRID:AB_790003
- Product name
- Mouse Monoclonal Glucagon Antibody
- Antibody type
- Monoclonal
- Description
- Unpurified. The antibody reacts specifically against pancreatic glucagon and exhibits only very weak cross-reaction with gut glucagon (enteroglucagon).Glucagon (K79bB10)
- Reactivity
- Human, Mouse, Rat, Canine, Feline, Guinea Pig, Porcine, Rabbit
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes.
PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells.
Lu TT, Heyne S, Dror E, Casas E, Leonhardt L, Boenke T, Yang CH, Sagar, Arrigoni L, Dalgaard K, Teperino R, Enders L, Selvaraj M, Ruf M, Raja SJ, Xie H, Boenisch U, Orkin SH, Lynn FC, Hoffman BG, Grün D, Vavouri T, Lempradl AM, Pospisilik JA
Cell metabolism 2018 Jun 5;27(6):1294-1308.e7
Cell metabolism 2018 Jun 5;27(6):1294-1308.e7
PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells.
Zehetner J, Danzer C, Collins S, Eckhardt K, Gerber PA, Ballschmieter P, Galvanovskis J, Shimomura K, Ashcroft FM, Thorens B, Rorsman P, Krek W
Genes & development 2008 Nov 15;22(22):3135-46
Genes & development 2008 Nov 15;22(22):3135-46
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
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- Experimental details
- Immunohistochemistry: Glucagon Antibody (K79bB10) [NB600-1506] - Mouse pancreatic islet alpha cells were stained using Monoclonal Anti-Glucagon, clone no. K79bB10, Anti-Mouse IgG-peroxidase and AEC substrate (red). The tissue was counterstained with hematoxylin (blue).
