Antibody data
- Antibody Data
- Antigen structure
- References [48]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- ABIN617889 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Glucagon (GCG) antibody
- Antibody type
- Polyclonal
- Description
- Whole Serum
- Reactivity
- Human, Mouse, Rat, Chicken/Avian, Porcine
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mL
- Storage
- After reconstitution, use immediately or refrigerate at 2 - 8°C up to 2 days. For long-term storage aliquot antibody and freeze at -15°C or lower. Avoid repeated freeze/thaw cycles.
Submitted references Fetal pancreas transplants are dependent on prolactin for their development and prevent type 1 diabetes in syngeneic but not allogeneic mice.
Dicer1 is required to repress neuronal fate during endocrine cell maturation.
Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors.
Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx.
Glucagon signaling modulates sweet taste responsiveness.
Inconsistent formation and nonfunction of insulin-positive cells from pancreatic endoderm derived from human embryonic stem cells in athymic nude rats.
CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling.
Beta cells within single human islets originate from multiple progenitors.
Tumour suppressor menin is essential for development of the pancreatic endocrine cells.
The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells.
p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors.
Anti-diabetic activity of SMK001, a poly herbal formula in streptozotocin induced diabetic rats: therapeutic study.
Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice.
Beta-cell deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes.
An immunohistochemical study of the pancreatic endocrine cells of the nude mouse, Balb/c-nu/nu.
Direct evidence of attempted beta cell regeneration in an 89-year-old patient with recent-onset type 1 diabetes.
Postprandial suppression of glucagon secretion depends on intact pulsatile insulin secretion: further evidence for the intraislet insulin hypothesis.
Ex vivo analysis of acinar and endocrine cell development in the human embryonic pancreas.
Changes of the gastric endocrine cells in the C57BL/6 mouse after implantation of murine lung carcinoma: an immunohistochemical quantitative study.
Comparison of genetic alterations in neuroendocrine tumors: frequent loss of chromosome 18 in ileal carcinoid tumors.
Distribution and frequency of endocrine cells in the pancreas of the ddY mouse: an immunohistochemical study.
Role for VPAC2 receptor-mediated signals in pancreas development.
Immunohistochemical study of the pancreatic endocrine cells in the BALB/c mice: an unique distributional pattern of glucagon.
Neogenesis of beta-cells in adult BETA2/NeuroD-deficient mice.
Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation.
A neuroendocrine/small cell prostate carcinoma xenograft-LuCaP 49.
Epidermal growth factor increases undifferentiated pancreatic embryonic cells in vitro: a balance between proliferation and differentiation.
Requirement of Math1 for secretory cell lineage commitment in the mouse intestine.
Up-regulation of clusterin (sulfated glycoprotein-2) in pancreatic islet cells upon streptozotocin injection to rats.
Colocalization of somatostatin receptor sst5 and insulin in rat pancreatic beta-cells.
Maternal adrenocortical hormones maintain the early development of pancreatic B cells in the fetal rat.
Specialized neuropeptide Y- and glucagon-like immunoreactive amacrine cells in the peripheral retina of the turtle.
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice.
Tissue-specific and developmental regulation of the rat insulin II gene enhancer, RIPE3, in transgenic mice.
Islet cell proliferation and apoptosis in insulin-like growth factor binding protein-1 in transgenic mice.
Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas.
Immunohistochemical study of enteric nervous system after small bowel transplantation in humans.
Somatostatin concentrations in the pancreatic-intestinal tissues of the sea lamprey, Petromyzon marinus L., at various periods of its life cycle.
An immunocytochemical study of the development of the olfactory system in the three-spined stickleback (Gasterosteus aculeatus L., Teleostei).
Phylogenetic study of serotonin-immunoreactive structures in the pancreas of various vertebrates.
Human pancreatic islet cell specific 38 kilodalton autoantigen identified by cytomegalovirus-induced monoclonal islet cell autoantibody.
Neuropeptide diversity in Ascaris: an immunocytochemical study.
Neuroendocrine dysdifferentiation and bombesin production in carcinogen-induced hepatocellular rat tumours.
Suppression of sleep-induced growth hormone secretion by anticholinergic agent abolishes dawn phenomenon.
Immunocytochemical characterization of glucagon-immunoreactive cells using monoclonal antibodies to pancreatic glucagon.
Catecholamine-containing pancreatic islet cells of the domestic fowl. Light, fluorescence and electron microscopy, and immunohistochemistry.
Selective localization of the parathyroid secretory protein-I/adrenal medulla chromogranin A protein family in a wide variety of endocrine cells of the rat.
An immunocytochemical survey of endocrine cells in the gastrointestinal tract of chicks at hatching.
Fourcade G, Colombo BM, Grégoire S, Baeyens A, Rachdi L, Guez F, Goffin V, Scharfmann R, Salomon BL
Diabetes 2013 May;62(5):1646-55
Diabetes 2013 May;62(5):1646-55
Dicer1 is required to repress neuronal fate during endocrine cell maturation.
Kanji MS, Martin MG, Bhushan A
Diabetes 2013 May;62(5):1602-11
Diabetes 2013 May;62(5):1602-11
Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors.
Butler AE, Campbell-Thompson M, Gurlo T, Dawson DW, Atkinson M, Butler PC
Diabetes 2013 Jul;62(7):2595-604
Diabetes 2013 Jul;62(7):2595-604
Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx.
Dhawan S, Georgia S, Tschen SI, Fan G, Bhushan A
Developmental cell 2011 Apr 19;20(4):419-29
Developmental cell 2011 Apr 19;20(4):419-29
Glucagon signaling modulates sweet taste responsiveness.
Elson AE, Dotson CD, Egan JM, Munger SD
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Oct;24(10):3960-9
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Oct;24(10):3960-9
Inconsistent formation and nonfunction of insulin-positive cells from pancreatic endoderm derived from human embryonic stem cells in athymic nude rats.
Matveyenko AV, Georgia S, Bhushan A, Butler PC
American journal of physiology. Endocrinology and metabolism 2010 Nov;299(5):E713-20
American journal of physiology. Endocrinology and metabolism 2010 Nov;299(5):E713-20
CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling.
Schulthess FT, Paroni F, Sauter NS, Shu L, Ribaux P, Haataja L, Strieter RM, Oberholzer J, King CC, Maedler K
Cell metabolism 2009 Feb;9(2):125-39
Cell metabolism 2009 Feb;9(2):125-39
Beta cells within single human islets originate from multiple progenitors.
Scharfmann R, Xiao X, Heimberg H, Mallet J, Ravassard P
PloS one 2008;3(10):e3559
PloS one 2008;3(10):e3559
Tumour suppressor menin is essential for development of the pancreatic endocrine cells.
Fontanière S, Duvillié B, Scharfmann R, Carreira C, Wang ZQ, Zhang CX
The Journal of endocrinology 2008 Nov;199(2):287-98
The Journal of endocrinology 2008 Nov;199(2):287-98
The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells.
Gierl MS, Karoulias N, Wende H, Strehle M, Birchmeier C
Genes & development 2006 Sep 1;20(17):2465-78
Genes & development 2006 Sep 1;20(17):2465-78
p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors.
Georgia S, Soliz R, Li M, Zhang P, Bhushan A
Developmental biology 2006 Oct 1;298(1):22-31
Developmental biology 2006 Oct 1;298(1):22-31
Anti-diabetic activity of SMK001, a poly herbal formula in streptozotocin induced diabetic rats: therapeutic study.
Kim JD, Kang SM, Seo BI, Choi HY, Choi HS, Ku SK
Biological & pharmaceutical bulletin 2006 Mar;29(3):477-82
Biological & pharmaceutical bulletin 2006 Mar;29(3):477-82
Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice.
Le May C, Chu K, Hu M, Ortega CS, Simpson ER, Korach KS, Tsai MJ, Mauvais-Jarvis F
Proceedings of the National Academy of Sciences of the United States of America 2006 Jun 13;103(24):9232-7
Proceedings of the National Academy of Sciences of the United States of America 2006 Jun 13;103(24):9232-7
Beta-cell deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes.
Matveyenko AV, Butler PC
Diabetes 2006 Jul;55(7):2106-14
Diabetes 2006 Jul;55(7):2106-14
An immunohistochemical study of the pancreatic endocrine cells of the nude mouse, Balb/c-nu/nu.
Ku SK, Lee HS
European journal of histochemistry : EJH 2006 Jan-Mar;50(1):61-8
European journal of histochemistry : EJH 2006 Jan-Mar;50(1):61-8
Direct evidence of attempted beta cell regeneration in an 89-year-old patient with recent-onset type 1 diabetes.
Meier JJ, Lin JC, Butler AE, Galasso R, Martinez DS, Butler PC
Diabetologia 2006 Aug;49(8):1838-44
Diabetologia 2006 Aug;49(8):1838-44
Postprandial suppression of glucagon secretion depends on intact pulsatile insulin secretion: further evidence for the intraislet insulin hypothesis.
Meier JJ, Kjems LL, Veldhuis JD, Lefèbvre P, Butler PC
Diabetes 2006 Apr;55(4):1051-6
Diabetes 2006 Apr;55(4):1051-6
Ex vivo analysis of acinar and endocrine cell development in the human embryonic pancreas.
Castaing M, Duvillié B, Quemeneur E, Basmaciogullari A, Scharfmann R
Developmental dynamics : an official publication of the American Association of Anatomists 2005 Oct;234(2):339-45
Developmental dynamics : an official publication of the American Association of Anatomists 2005 Oct;234(2):339-45
Changes of the gastric endocrine cells in the C57BL/6 mouse after implantation of murine lung carcinoma: an immunohistochemical quantitative study.
Ku SK, Lee HS, Byun JS, Seo BI, Lee JH
World journal of gastroenterology 2005 Mar 7;11(9):1317-23
World journal of gastroenterology 2005 Mar 7;11(9):1317-23
Comparison of genetic alterations in neuroendocrine tumors: frequent loss of chromosome 18 in ileal carcinoid tumors.
Wang GG, Yao JC, Worah S, White JA, Luna R, Wu TT, Hamilton SR, Rashid A
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005 Aug;18(8):1079-87
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005 Aug;18(8):1079-87
Distribution and frequency of endocrine cells in the pancreas of the ddY mouse: an immunohistochemical study.
Ku SK, Lee HS
European journal of histochemistry : EJH 2005 Apr-Jun;49(2):125-30
European journal of histochemistry : EJH 2005 Apr-Jun;49(2):125-30
Role for VPAC2 receptor-mediated signals in pancreas development.
Rachdi L, Marie JC, Scharfmann R
Diabetes 2003 Jan;52(1):85-92
Diabetes 2003 Jan;52(1):85-92
Immunohistochemical study of the pancreatic endocrine cells in the BALB/c mice: an unique distributional pattern of glucagon.
Ku SK, Lee HS, Lee JH
Journal of veterinary science 2002 Sep;3(3):167-73
Journal of veterinary science 2002 Sep;3(3):167-73
Neogenesis of beta-cells in adult BETA2/NeuroD-deficient mice.
Huang HP, Chu K, Nemoz-Gaillard E, Elberg D, Tsai MJ
Molecular endocrinology (Baltimore, Md.) 2002 Mar;16(3):541-51
Molecular endocrinology (Baltimore, Md.) 2002 Mar;16(3):541-51
Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation.
Elghazi L, Cras-Méneur C, Czernichow P, Scharfmann R
Proceedings of the National Academy of Sciences of the United States of America 2002 Mar 19;99(6):3884-9
Proceedings of the National Academy of Sciences of the United States of America 2002 Mar 19;99(6):3884-9
A neuroendocrine/small cell prostate carcinoma xenograft-LuCaP 49.
True LD, Buhler K, Quinn J, Williams E, Nelson PS, Clegg N, Macoska JA, Norwood T, Liu A, Ellis W, Lange P, Vessella R
The American journal of pathology 2002 Aug;161(2):705-15
The American journal of pathology 2002 Aug;161(2):705-15
Epidermal growth factor increases undifferentiated pancreatic embryonic cells in vitro: a balance between proliferation and differentiation.
Cras-Méneur C, Elghazi L, Czernichow P, Scharfmann R
Diabetes 2001 Jul;50(7):1571-9
Diabetes 2001 Jul;50(7):1571-9
Requirement of Math1 for secretory cell lineage commitment in the mouse intestine.
Yang Q, Bermingham NA, Finegold MJ, Zoghbi HY
Science (New York, N.Y.) 2001 Dec 7;294(5549):2155-8
Science (New York, N.Y.) 2001 Dec 7;294(5549):2155-8
Up-regulation of clusterin (sulfated glycoprotein-2) in pancreatic islet cells upon streptozotocin injection to rats.
Park IS, Che YZ, Bendayan M, Kang SW, Min BH
The Journal of endocrinology 1999 Jul;162(1):57-65
The Journal of endocrinology 1999 Jul;162(1):57-65
Colocalization of somatostatin receptor sst5 and insulin in rat pancreatic beta-cells.
Mitra SW, Mezey E, Hunyady B, Chamberlain L, Hayes E, Foor F, Wang Y, Schonbrunn A, Schaeffer JM
Endocrinology 1999 Aug;140(8):3790-6
Endocrinology 1999 Aug;140(8):3790-6
Maternal adrenocortical hormones maintain the early development of pancreatic B cells in the fetal rat.
Komatsu S, Yamamoto M, Arishima K, Eguchi Y
Journal of anatomy 1998 Nov;193 ( Pt 4):551-7
Journal of anatomy 1998 Nov;193 ( Pt 4):551-7
Specialized neuropeptide Y- and glucagon-like immunoreactive amacrine cells in the peripheral retina of the turtle.
Wetzel RK, Eldred WD
Visual neuroscience 1997 Sep-Oct;14(5):867-77
Visual neuroscience 1997 Sep-Oct;14(5):867-77
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice.
Naya FJ, Huang HP, Qiu Y, Mutoh H, DeMayo FJ, Leiter AB, Tsai MJ
Genes & development 1997 Sep 15;11(18):2323-34
Genes & development 1997 Sep 15;11(18):2323-34
Tissue-specific and developmental regulation of the rat insulin II gene enhancer, RIPE3, in transgenic mice.
Stellrecht CM, DeMayo FJ, Finegold MJ, Tsai MJ
The Journal of biological chemistry 1997 Feb 7;272(6):3567-72
The Journal of biological chemistry 1997 Feb 7;272(6):3567-72
Islet cell proliferation and apoptosis in insulin-like growth factor binding protein-1 in transgenic mice.
Dheen ST, Rajkumar K, Murphy LJ
The Journal of endocrinology 1997 Dec;155(3):551-8
The Journal of endocrinology 1997 Dec;155(3):551-8
Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas.
Pang K, Mukonoweshuro C, Wong GG
Proceedings of the National Academy of Sciences of the United States of America 1994 Sep 27;91(20):9559-63
Proceedings of the National Academy of Sciences of the United States of America 1994 Sep 27;91(20):9559-63
Immunohistochemical study of enteric nervous system after small bowel transplantation in humans.
Sugitani A, Reynolds JC, Todo S
Digestive diseases and sciences 1994 Nov;39(11):2448-56
Digestive diseases and sciences 1994 Nov;39(11):2448-56
Somatostatin concentrations in the pancreatic-intestinal tissues of the sea lamprey, Petromyzon marinus L., at various periods of its life cycle.
Elliott WM, Youson JH
Comparative biochemistry and physiology. A, Comparative physiology 1991;99(3):357-60
Comparative biochemistry and physiology. A, Comparative physiology 1991;99(3):357-60
An immunocytochemical study of the development of the olfactory system in the three-spined stickleback (Gasterosteus aculeatus L., Teleostei).
Honkanen T, Ekström P
Anatomy and embryology 1991;184(5):469-77
Anatomy and embryology 1991;184(5):469-77
Phylogenetic study of serotonin-immunoreactive structures in the pancreas of various vertebrates.
Ding WG, Fujimura M, Tooyama I, Kimura H
Cell and tissue research 1991 Feb;263(2):237-43
Cell and tissue research 1991 Feb;263(2):237-43
Human pancreatic islet cell specific 38 kilodalton autoantigen identified by cytomegalovirus-induced monoclonal islet cell autoantibody.
Pak CY, Cha CY, Rajotte RV, McArthur RG, Yoon JW
Diabetologia 1990 Sep;33(9):569-72
Diabetologia 1990 Sep;33(9):569-72
Neuropeptide diversity in Ascaris: an immunocytochemical study.
Sithigorngul P, Stretton AO, Cowden C
The Journal of comparative neurology 1990 Apr 15;294(3):362-76
The Journal of comparative neurology 1990 Apr 15;294(3):362-76
Neuroendocrine dysdifferentiation and bombesin production in carcinogen-induced hepatocellular rat tumours.
Seglen PO, Skomedal H, Saeter G, Schwarze PE, Nesland JM
Carcinogenesis 1989 Jan;10(1):21-5
Carcinogenesis 1989 Jan;10(1):21-5
Suppression of sleep-induced growth hormone secretion by anticholinergic agent abolishes dawn phenomenon.
Davidson MB, Harris MD, Ziel FH, Rosenberg CS
Diabetes 1988 Feb;37(2):166-71
Diabetes 1988 Feb;37(2):166-71
Immunocytochemical characterization of glucagon-immunoreactive cells using monoclonal antibodies to pancreatic glucagon.
Buchan AM, Gregor M, Riecken EO
Histochemistry 1987;87(1):79-83
Histochemistry 1987;87(1):79-83
Catecholamine-containing pancreatic islet cells of the domestic fowl. Light, fluorescence and electron microscopy, and immunohistochemistry.
Watanabe T, Chikazawa H, Yamada J
Cell and tissue research 1984;237(2):239-44
Cell and tissue research 1984;237(2):239-44
Selective localization of the parathyroid secretory protein-I/adrenal medulla chromogranin A protein family in a wide variety of endocrine cells of the rat.
Cohn DV, Elting JJ, Frick M, Elde R
Endocrinology 1984 Jun;114(6):1963-74
Endocrinology 1984 Jun;114(6):1963-74
An immunocytochemical survey of endocrine cells in the gastrointestinal tract of chicks at hatching.
Rawdon BB, Andrew A
Cell and tissue research 1981;220(2):279-92
Cell and tissue research 1981;220(2):279-92
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