67286-1-Ig

antibody from Proteintech Group

Targeting: GCG GLP-1, GLP1, GLP2, GRPP

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

67286-1-Ig

Provider

Proteintech Group

Product name

Glucagon antibody

Antibody type

Monoclonal

Description

Glucagon antibody (Cat. #67286-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse and has been validated for the following applications: IF, IHC,ELISA.

Reactivity

Human, Mouse

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2A8G1

Vial size

20ul, 150ul

References

Submitted references

Car@PLGA-NPs target gut microbiota-ER stress axis to combat diabetes.

Zhao W, Chen L, Qing J, Zhao Z, Xiong L, Tong P, Huang Z, Chen Y
Frontiers in cellular and infection microbiology 2025;15:1667023

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Bifidobacterium longum subsp. longum B-53 Alleviated Abnormalities of Glycolipid Metabolism and Oxidative Stress in T2DM Mice Through Regulating Gut Microbiota and GLP-1 Secretion.

Chen J, Zhang L, Cheng Z, Zhang Y, Li X, Zheng S, Zhang N, Li B, Liu F, Jiao Y
Journal of agricultural and food chemistry 2025 Sep 24;73(38):24169-24186

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Chromogranin A and catestatin regulate pancreatic islet homeostasis, endocrine function, and neurotransmitter signaling.

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Communications biology 2025 Nov 26;8(1):1684

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A critical role for Phocaeicola vulgatus in negatively impacting metformin response in diabetes.

Chen M, Peng Y, Hu Y, Kang Z, Chen T, Zhang Y, Chen X, Li Q, Yuan Z, Wu Y, Xu H, Zhou G, Liu T, Zhou H, Yuan C, Huang W, Zhang W
Acta pharmaceutica Sinica. B 2025 May;15(5):2511-2528

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Semaglutide alleviates the pancreatic β cell function via the METTL14 signaling and modulating gut microbiota in type 2 diabetes mellitus mice.

Luo Y, Li JE, Zeng H, Zhang Y, Yang S, Liu J
Life sciences 2025 Jan 15;361:123328

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ciBAR1 loss in mice causes laterality defects, pancreatic degeneration, and altered glucose tolerance.

Kim EN, Li FQ, Takemaru KI
Life science alliance 2025 Feb;8(2)

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Boosting the engraftment of subcutaneously transplanted pancreatic islets by nanofat.

Wrublewsky S, Bickelmann C, Meßmer LS, Wilden C, Berhorst C, Prates-Roma L, Morgan B, Rother S, Menger MD, Laschke MW, Weinzierl A, Ampofo E
Diabetes, obesity & metabolism 2025 Dec;27(12):7258-7274

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Liensinine alleviates type 2 diabetes mellitus through modulating the pancreatic β cell function and gut microbiota.

Luo Y, Liu X, Zhang Y, Wu J, Wang Y, Nie J, Ying Y, Huang S
Genes & nutrition 2025 Dec 24;20(1):29

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Both subcutaneous semaglutide and calorie restriction improves pancreatic cell hyperplasia and gut microbiota in high-fat diet-induced obese mice.

Luo Y, Yang S, Zeng H, Liu S, Zhang Y, Li JE, Liu J
Nutrition & metabolism 2025 Aug 7;22(1):95

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Sex-Specific Differences in the Revascularization of Grafted Pancreatic Islets.

Wrublewsky S, Widmann AV, Bickelmann C, Rafacho A, Roma LP, Laschke MW, Ampofo E
Cells 2025 Aug 29;14(17)

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Chromogranin A and catestatin regulate pancreatic islet homeostasis, endocrine function, and neurotransmitter signaling.

Muntjewerff EM, Epremidze D, Nezhyva M, Kal S, Rohm TV, Tang K, Singh K, Espes D, Jati S, Bootsma M, Mannaa AM, Ikebuchi H, Nilsson AM, Rajasekaran M, Andrén PE, Jansson ET, Mahata SK, Christoffersson G
bioRxiv : the preprint server for biology 2025 Aug 27;

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Cancer-Associated Endocrine Cells Participate in Pancreatic Carcinogenesis.

Chen Y, Yin X, Xu R, Ruze R, Song J, Yin C, Hu C, Wang C, Xu Q, Zhao Y
Gastroenterology 2024 Nov;167(6):1167-1182.e23

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Long non-coding RNA LncCplx2 regulates glucose homeostasis and pancreatic β cell function.

Wang L, Hu L, Wang X, Geng Z, Wan M, Hao J, Liu H, Fan Y, Xu T, Li Z
Molecular metabolism 2024 Feb;80:101878

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Spint1 disruption in mouse pancreas leads to glucose intolerance and impaired insulin production involving HEPSIN/MAFA.

Lin HH, Yu IS, Cheng MS, Chang TJ, Lin HY, Chang YC, Ko CJ, Chen PH, Lin SW, Huang TC, Huang SY, Chen TY, Kan KW, Huang HP, Lee MS
Nature communications 2024 Dec 3;15(1):10537

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Mesenchymal stromal cells ameliorate mitochondrial dysfunction in α cells and hyperglucagonemia in type 2 diabetes via SIRT1/FoxO3a signaling.

Song J, Wang L, Wang L, Guo X, He Q, Cui C, Hu H, Zang N, Yang M, Yan F, Liang K, Wang C, Liu F, Sun Y, Sun Z, Lai H, Hou X, Chen L
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Bacteroides ovatus accelerates metformin-induced vitamin B12 deficiency in type 2 diabetes patients by accumulating cobalamin.

Chen M, Shu Y, Li Q, Kang Z, Liu T, Zhou H, Huang W, Zhang W
NPJ biofilms and microbiomes 2023 Jul 24;9(1):51

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Dendrobium officinale leaf polysaccharides ameliorated hyperglycemia and promoted gut bacterial associated SCFAs to alleviate type 2 diabetes in adult mice.

Fang J, Lin Y, Xie H, Farag MA, Feng S, Li J, Shao P
Food chemistry: X 2022 Mar 30;13:100207

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Mof acetyltransferase inhibition ameliorates glucose intolerance and islet dysfunction of type 2 diabetes via targeting pancreatic α-cells.

Guo X, Cui C, Song J, He Q, Zang N, Hu H, Wang X, Li D, Wang C, Hou X, Li X, Liang K, Yan F, Chen L
Molecular and cellular endocrinology 2021 Nov 1;537:111425