Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 18507-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18507-1-AP, RRID:AB_10644334
- Product name
- PLAP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PLAP antibody (Cat. #18507-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Fracture-Induced Immunological Cascades Trigger Rapid Systemic Bone Loss via Osteocyte-Regulated Osteoclastogenesis.
Cranial repair-promoting effect of oxidised sodium alginate/amino gelatine injectable hydrogel loaded with deer antler blood peptides.
METTL3-mediated m6A modification of circSTAT6 modulates miR-188-3p/Beclin1 axis to promote osteogenic differentiation of mesenchymal stem cells.
Role and mechanism of Actein on condylar bone metabolism in APOE deletion-induced osteoporotic mice.
Long non-coding RNA NRIR inhibits osteogenesis in peri-implantitis by promoting NLRP3 inflammasome-mediated macrophage pyroptosis.
The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ.
Ultrasound-triggered piezoelectric polyetheretherketone with boosted osteogenesis via regulating Akt/GSK3β/β-catenin pathway.
Influence of METTL3 knockdown on PDLSC osteogenesis in E. coli LPS-induced inflammation.
Biomimetic cryogel promotes the repair of osteoporotic bone defects through altering the ROS niche via down-regulating the ROMO1.
Mechanically induced M2 macrophages are involved in bone remodeling of the midpalatal suture during palatal expansion.
Four novel mutations identification in 17 beta-hydroxysteroid dehydrogenase-3 deficiency and our clinical experience: possible benefits of early treatment.
NRF2 is a critical regulator and therapeutic target of metal implant particle-incurred bone damage.
Long noncoding RNA ZFAS1 suppresses osteogenic differentiation of bone marrow-derived mesenchymal stem cells by upregulating miR-499-EPHA5 axis.
Primary cilia regulate gastric cancer-induced bone loss via cilia/Wnt/β-catenin signaling pathway.
6-Bromoindirubin-3'-oxime Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells and Facilitates Bone Regeneration in a Mouse Periodontitis Model.
Liraglutide regulates bone destruction and exhibits anti-inflammatory effects in periodontitis in vitro and in vivo.
New aspects of antiproliferative activity of 4-hydroxybenzyl isothiocyanate, a natural H(2)S-donor.
Sun L, Kuang S, Li Y, Wang G, Sun J, Zhou F, Zhang C
ImmunoTargets and therapy 2025;14:849-875
ImmunoTargets and therapy 2025;14:849-875
Cranial repair-promoting effect of oxidised sodium alginate/amino gelatine injectable hydrogel loaded with deer antler blood peptides.
Yu T, Ding Q, Wang N, Zhang S, Cheng Z, Zhao C, Li Q, Ding C, Liu W
International journal of biological macromolecules 2025 May;305(Pt 1):141116
International journal of biological macromolecules 2025 May;305(Pt 1):141116
METTL3-mediated m6A modification of circSTAT6 modulates miR-188-3p/Beclin1 axis to promote osteogenic differentiation of mesenchymal stem cells.
Luo Y, Shi Y, Wu Y, Cao H
Journal of orthopaedic surgery and research 2025 Mar 26;20(1):313
Journal of orthopaedic surgery and research 2025 Mar 26;20(1):313
Role and mechanism of Actein on condylar bone metabolism in APOE deletion-induced osteoporotic mice.
Zhou L, Li Y, Ma J, Zhang Q, Tang S, Zou K, Zeng Q, Huang H, Jin H, Zhang Q, Feng J
Bone 2025 Jan;190:117304
Bone 2025 Jan;190:117304
Long non-coding RNA NRIR inhibits osteogenesis in peri-implantitis by promoting NLRP3 inflammasome-mediated macrophage pyroptosis.
Wang L, Zhao R, Xiao K, Zhou Y, Liu Q, Yu K
International immunopharmacology 2025 Feb 20;148:114180
International immunopharmacology 2025 Feb 20;148:114180
The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ.
Luo X, Huang B, Xu P, Wang H, Zhang B, Lin L, Liao J, Hu M, Liu X, Huang J, Fu Y, Kilby MD, Kellems RE, Fan X, Xia Y, Baker PN, Qi H, Tong C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2404983
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2404983
Ultrasound-triggered piezoelectric polyetheretherketone with boosted osteogenesis via regulating Akt/GSK3β/β-catenin pathway.
Li Y, Fan Y, Zhao S, Cheng B
Journal of nanobiotechnology 2024 Sep 5;22(1):539
Journal of nanobiotechnology 2024 Sep 5;22(1):539
Influence of METTL3 knockdown on PDLSC osteogenesis in E. coli LPS-induced inflammation.
Chen H, Peng L, Wang Z, He Y, Zhang X
Oral diseases 2024 Jul;30(5):3225-3238
Oral diseases 2024 Jul;30(5):3225-3238
Biomimetic cryogel promotes the repair of osteoporotic bone defects through altering the ROS niche via down-regulating the ROMO1.
Liu H, Pan W, Liu H, Xie D, Liao L
International journal of biological macromolecules 2024 Feb;257(Pt 1):128481
International journal of biological macromolecules 2024 Feb;257(Pt 1):128481
Mechanically induced M2 macrophages are involved in bone remodeling of the midpalatal suture during palatal expansion.
Li L, Zhai M, Cheng C, Cui S, Wang J, Zhang Z, Liu J, Wei F
Progress in orthodontics 2024 Aug 5;25(1):30
Progress in orthodontics 2024 Aug 5;25(1):30
Four novel mutations identification in 17 beta-hydroxysteroid dehydrogenase-3 deficiency and our clinical experience: possible benefits of early treatment.
Wang Y, Xu Y, Zhang H, Yin D, Pan Y, He X, Li S, Cheng Z, Zhu G, Zhao T, Huang H, Zhu M
Frontiers in endocrinology 2023;14:1267967
Frontiers in endocrinology 2023;14:1267967
NRF2 is a critical regulator and therapeutic target of metal implant particle-incurred bone damage.
Dong J, Zhang L, Ruan B, Lv Z, Wang H, Wang Y, Jiang Q, Cao W
Biomaterials 2022 Sep;288:121742
Biomaterials 2022 Sep;288:121742
Long noncoding RNA ZFAS1 suppresses osteogenic differentiation of bone marrow-derived mesenchymal stem cells by upregulating miR-499-EPHA5 axis.
Wu J, Lin T, Gao Y, Li X, Yang C, Zhang K, Wang C, Zhou X
Molecular and cellular endocrinology 2022 Jan 1;539:111490
Molecular and cellular endocrinology 2022 Jan 1;539:111490
Primary cilia regulate gastric cancer-induced bone loss via cilia/Wnt/β-catenin signaling pathway.
Xu J, Deng X, Wu X, Zhu H, Zhu Y, Liu J, Chen Q, Yuan C, Liu G, Wang C
Aging 2021 Mar 9;13(6):8989-9010
Aging 2021 Mar 9;13(6):8989-9010
6-Bromoindirubin-3'-oxime Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells and Facilitates Bone Regeneration in a Mouse Periodontitis Model.
Shen S, Zhang Y, Zhang S, Wang B, Shang L, Shao J, Lin M, Cui Y, Sun S, Ge S
ACS biomaterials science & engineering 2021 Jan 11;7(1):232-241
ACS biomaterials science & engineering 2021 Jan 11;7(1):232-241
Liraglutide regulates bone destruction and exhibits anti-inflammatory effects in periodontitis in vitro and in vivo.
Zhang Y, Yuan X, Wu Y, Pei M, Yang M, Wu X, Pang Y, Wang J
Journal of dentistry 2020 Mar;94:103310
Journal of dentistry 2020 Mar;94:103310
New aspects of antiproliferative activity of 4-hydroxybenzyl isothiocyanate, a natural H(2)S-donor.
Jurkowska H, Wróbel M, Szlęzak D, Jasek-Gajda E
Amino acids 2018 Jun;50(6):699-709
Amino acids 2018 Jun;50(6):699-709
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human placenta tissue were subjected to SDS PAGE followed by western blot with 18507-1-AP( ALPP Antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human placenta using 18507-1-AP(ALPP antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The PLAP antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PLAP. This antibody recognizes human, mouse antigen. The PLAP antibody has been validated for the following applications: ELISA, IHC, WB analysis.