BS6641

antibody from Bioworld Technology, Inc
Targeting: EIF6 b(2)gcn, EIF3A, ITGB4BP, p27BBP
Provider product page for BS6641
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6641 - Provider product page
Provider
Bioworld Technology, Inc
Product name
eIF6 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human eIF6.
Description
Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May behave as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (GNB2L1)-dependent protein kinase C activity.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
EIF6 protein structure - BS6641 shown in red.