Tissue expression
Cell line expression
Protein structure
EIF6
Eukaryotic translation initiation factor 6b(2)gcn, EIF3A, ITGB4BP, p27BBP
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Top validated antibodies |
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Proteintech Group | 10291-1-AP | 6 references | Polyclonal |
WB
EL
ICC
IHC
FC
|
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Invitrogen Antibodies | PA5-31066 | 1 references | Polyclonal |
WB
ICC
IHC
OA |
|
Atlas Antibodies | HPA040873 | Polyclonal |
WB
ICC
IHC
|
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Novus Biologicals | NBP2-13954 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Cell Signaling Technology, Inc | 3263 | Polyclonal |
WB
ICC
IP
IHC |
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider