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- Product number
- ABIN564777 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3) (AA 1-439) antibody
- Antibody type
- Monoclonal
- Antigen
- LILRA3 (AAH28208.1, 1 a.a. ~ 439 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: MTSILTVLICLGLSLDPRTH VQAGPLPKPTLWAEPGSVIT QGSPVTLRCQGSLETQEYHL YREKKTALWITRIPQELVKK GQFPILSITWEHAGRYCCIY GSHTVGLSESSDPLELVVTG AYSKPTLSALPSPVVTSGGN VTIQCDSQVAFDGFILCKEG EDEHPQCLNSHSHARGSSRA IFSVGPVSPSRRWSYRCYGY DSRAPYVWSLPSDLLGLLVP GVSKKPSLSVQPGPVVAPGE KLTFQCGSDAGYDRFVLYKE WGRDFLQRPGRQPQAGLSQA NFTLGPVSRSYGGQYTCSGA YNLSSEWSAPSDPLDILITG QIRARPFLSVRPGPTVASGE NVTLLCQSQGGMHTFLLTKE GAADSPLRLKSKRQSHKYQA EFPMSPVTSAHAGTYRCYGS LSSNPYLLTHPSDPLELVVS GAAETLSPPQNKSDSKAGE
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-439
- Isotype
- IgG
- Antibody clone number
- 2E9
- Vial size
- 100 μg
- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Submitted references Serum Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3) Is Increased in Patients with Multiple Sclerosis and Is a Strong Independent Indicator of Disease Severity; 6.7kbp LILRA3 Gene Deletion Is Not Associated with Diseases Susceptibility.
Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66.
TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads.
Glycosylation in a mammalian expression system is critical for the production of functionally active leukocyte immunoglobulin-like receptor A3 protein.
Soluble LILRA3, a potential natural antiinflammatory protein, is increased in patients with rheumatoid arthritis and is tightly regulated by interleukin 10, tumor necrosis factor-alpha, and interferon-gamma.
An H, Lim C, Guillemin GJ, Vollmer-Conna U, Rawlinson W, Bryant K, Tedla N
PloS one 2016;11(2):e0149200
PloS one 2016;11(2):e0149200
Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66.
An H, Brettle M, Lee T, Heng B, Lim CK, Guillemin GJ, Lord MS, Klotzsch E, Geczy CL, Bryant K, Fath T, Tedla N
Journal of cell science 2016 Mar 15;129(6):1198-209
Journal of cell science 2016 Mar 15;129(6):1198-209
TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads.
Low HZ, Ahrenstorf G, Pommerenke C, Habermann N, Schughart K, Ordóñez D, Stripecke R, Wilk E, Witte T
Retrovirology 2016 Mar 12;13:15
Retrovirology 2016 Mar 12;13:15
Glycosylation in a mammalian expression system is critical for the production of functionally active leukocyte immunoglobulin-like receptor A3 protein.
Lee TH, Mitchell A, Liu Lau S, An H, Rajeaskariah P, Wasinger V, Raftery M, Bryant K, Tedla N
The Journal of biological chemistry 2013 Nov 15;288(46):32873-85
The Journal of biological chemistry 2013 Nov 15;288(46):32873-85
Soluble LILRA3, a potential natural antiinflammatory protein, is increased in patients with rheumatoid arthritis and is tightly regulated by interleukin 10, tumor necrosis factor-alpha, and interferon-gamma.
An H, Chandra V, Piraino B, Borges L, Geczy C, McNeil HP, Bryant K, Tedla N
The Journal of rheumatology 2010 Aug 1;37(8):1596-606
The Journal of rheumatology 2010 Aug 1;37(8):1596-606
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