LILRA3

This gene encodes a member of a family of immunoreceptors that are expressed predominantly in monocytes and B cells, and at lower levels in dendritic cells and natural killer cells. The encoded protein lacks the transmembrane region found in other members of this family. It acts as a soluble receptor for class I major histocompatibility complex (MHC) antigens. Alternatively spliced transcript variants encoding different isoforms have been found. This gene is located in a cluster of related genes on chromosome 19 and is polymorphic in human populations, with many individuals containing a deletion of this genomic region. [provided by RefSeq, Mar 2014]

Description

Leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3

Predicted location

Protein family

-

Chromosome

19 (54799854 - 54809952)

Ensembl ID

ENSG00000170866  (ver. 74.37)

Orthologs

-

UniProt

 

neXtProt

 

Human splice variants

Protein structure