ABIN1706196

antibody from antibodies-online

Targeting: AIFM1 AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1706196

Provider

antibodies-online

Product name

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence at the C-terminus of human AIFM1, identical to the related rat and mouse sequences.Immunogen affinity purified.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

100 μg

Storage

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Cowchock syndrome is associated with a mutation in apoptosis-inducing factor.

Rinaldi C, Grunseich C, Sevrioukova IF, Schindler A, Horkayne-Szakaly I, Lamperti C, Landouré G, Kennerson ML, Burnett BG, Bönnemann C, Biesecker LG, Ghezzi D, Zeviani M, Fischbeck KH
American journal of human genetics 2012 Dec 7;91(6):1095-102

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Severe X-linked mitochondrial encephalomyopathy associated with a mutation in apoptosis-inducing factor.

Ghezzi D, Sevrioukova I, Invernizzi F, Lamperti C, Mora M, D'Adamo P, Novara F, Zuffardi O, Uziel G, Zeviani M
American journal of human genetics 2010 Apr 9;86(4):639-49

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Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death.

Yu SW, Andrabi SA, Wang H, Kim NS, Poirier GG, Dawson TM, Dawson VL
Proceedings of the National Academy of Sciences of the United States of America 2006 Nov 28;103(48):18314-9