AIFM1

gene product
AIF, CMTX4, NAMSD, PDCD8
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Aug 2015]
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805 antibodies from 43 providers.

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Novus Biologicals
40 antibodies
antibodies-online
265 antibodies
GeneTex
8 antibodies
Abnova Corporation
13 antibodies
Acris Antibodies GmbH
20 antibodies
OriGene
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Biorbyt
59 antibodies
Cell Signaling Technology, Inc
3 antibodies
Proteintech Group
1 antibody
Abgent
8 antibodies
NovoPro Bioscience Inc.
7 antibodies
Boster Biological Technology
3 antibodies
LifeSpan BioSciences, Inc.
168 antibodies
Invitrogen Antibodies
14 antibodies
R&D Systems
5 antibodies
St John's Laboratory
7 antibodies
Affinity Biosciences
2 antibodies
NSJ Bioreagents
6 antibodies
ProSci
2 antibodies
Atlas Antibodies
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
Enzo Life Sciences
3 antibodies
Bioworld Technology, Inc
1 antibody
Bethyl Laboratories
2 antibodies
Aviva Systems Biology
11 antibodies
Arigo
3 antibodies
RabMAbs
4 antibodies
Antibodies.com
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Creative Biolabs
13 antibodies
Creative Diagnostics
9 antibodies
MyBioSource
15 antibodies
EMD Millipore
5 antibodies
Abbiotec
2 antibodies
GenWay
9 antibodies
United States Biological
31 antibodies
RayBiotech, Inc.
5 antibodies
Abiocode, Inc.
1 antibody
eBioscience, An Affymetrix Company
1 antibody
Abbexa
3 antibodies
Exalpha Biologicals, Inc.
3 antibodies
Sigma-Aldrich
4 antibodies