AIFM1

gene product
AIF, CMTX4, NAMSD, PDCD8
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, May 2010]
More gene data

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
770 antibodies from 42 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
265 antibodies
GeneTex
8 antibodies
Novus Biologicals
38 antibodies
Abnova Corporation
13 antibodies
Acris Antibodies GmbH
20 antibodies
OriGene
20 antibodies
Invitrogen Antibodies
14 antibodies
Biorbyt
58 antibodies
Proteintech Group
1 antibody
Cell Signaling Technology, Inc
3 antibodies
Abgent
8 antibodies
R&D Systems
6 antibodies
NovoPro Bioscience Inc.
7 antibodies
Boster Biological Technology
3 antibodies
Affinity Biosciences
2 antibodies
LifeSpan BioSciences, Inc.
150 antibodies
St John's Laboratory
7 antibodies
NSJ Bioreagents
5 antibodies
ProSci
2 antibodies
Atlas Antibodies
1 antibody
Enzo Life Sciences
3 antibodies
Bioworld Technology, Inc
1 antibody
Bethyl Laboratories
2 antibodies
Aviva Systems Biology
11 antibodies
Arigo
3 antibodies
Rockland Immunochemicals, Inc.
1 antibody
RabMAbs
4 antibodies
Antibodies.com
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Creative Diagnostics
8 antibodies
MyBioSource
15 antibodies
EMD Millipore
5 antibodies
Abbiotec
2 antibodies
GenWay
9 antibodies
United States Biological
31 antibodies
RayBiotech, Inc.
5 antibodies
Abiocode, Inc.
1 antibody
eBioscience, An Affymetrix Company
1 antibody
Abbexa
3 antibodies
Exalpha Biologicals, Inc.
3 antibodies
Sigma-Aldrich
4 antibodies