Tissue expression
Cell line expression
Protein structure

AIFM1

Apoptosis inducing factor mitochondria associated 1
AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8 
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Aug 2015]
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900 antibodies from 47 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
4 antibodies
antibodies-online
265 antibodies
GeneTex
8 antibodies
Novus Biologicals
40 antibodies
Invitrogen Antibodies
46 antibodies
OriGene
24 antibodies
Abnova Corporation
13 antibodies
Acris Antibodies GmbH
20 antibodies
Cell Signaling Technology, Inc
3 antibodies
Biorbyt
69 antibodies
NSJ Bioreagents
8 antibodies
Abgent
8 antibodies
NovoPro Bioscience Inc.
7 antibodies
HUABIO Research
1 antibody
R&D Systems
5 antibodies
Boster Biological Technology
5 antibodies
Cusabio Biotech Co., Ltd
9 antibodies
Affinity Biosciences
2 antibodies
Everest Biotech
2 antibodies
ProSci
2 antibodies
Atlas Antibodies
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
St John's Laboratory
8 antibodies
Enzo Life Sciences
3 antibodies
Bioworld Technology, Inc
1 antibody
Bethyl Laboratories
2 antibodies
Aviva Systems Biology
11 antibodies
Rockland Immunochemicals, Inc.
1 antibody
Arigo
3 antibodies
RabMAbs
4 antibodies
Antibodies.com
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Creative Biolabs
17 antibodies
MyBioSource
15 antibodies
Abbexa
14 antibodies
Creative Diagnostics
9 antibodies
EMD Millipore
5 antibodies
Leading Biology
8 antibodies
Abbiotec
2 antibodies
GenWay
9 antibodies
United States Biological
31 antibodies
RayBiotech, Inc.
5 antibodies
Abiocode, Inc.
1 antibody
eBioscience, An Affymetrix Company
1 antibody
MilliporeSigma / Merck KGaA
5 antibodies