Tissue expression
Cell line expression

AIFM1

gene product
AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8 
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Aug 2015]
More gene data

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880 antibodies from 47 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
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antibodies-online
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8 antibodies
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40 antibodies
OriGene
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13 antibodies
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20 antibodies
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3 antibodies
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HUABIO Research
1 antibody
R&D Systems
5 antibodies
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5 antibodies
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St John's Laboratory
7 antibodies
Affinity Biosciences
2 antibodies
ProSci
2 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
Enzo Life Sciences
3 antibodies
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1 antibody
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2 antibodies
Aviva Systems Biology
11 antibodies
Arigo
3 antibodies
Atlas Antibodies
1 antibody
RabMAbs
4 antibodies
Antibodies.com
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Creative Biolabs
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MyBioSource
15 antibodies
Abbexa
14 antibodies
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8 antibodies
Abbiotec
2 antibodies
GenWay
9 antibodies
Rockland Immunochemicals, Inc.
1 antibody
United States Biological
31 antibodies
RayBiotech, Inc.
5 antibodies
Abiocode, Inc.
1 antibody
eBioscience, An Affymetrix Company
1 antibody
MilliporeSigma / Merck KGaA
5 antibodies
Exalpha Biologicals, Inc.
3 antibodies