M01571

antibody from Boster Biological Technology
Targeting: AIFM1 AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8
Provider product page for M01571
Western blot
Immunocytochemistry
Immunoprecipitation

Antibody data

Product number
M01571 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-AIF AIFM1 Rabbit Monoclonal Antibody
Antibody type
Monoclonal
Description
Monoclonal antibody for AIF/AIFM1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IP, IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat AIF/AIFM1 information: Molecular Weight: 66901 MW; Subcellular Localization: Mitochondrion intermembrane space. Mitochondrion inner membrane. Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Proteolytic cleavage during or just after translocation into the mitochondrial intermembrane space (IMS) results in the formation of an inner-membrane-anchored mature form (AIFmit). During apoptosis, further proteolytic processing leads to a mature form, which is confined to the mitochondrial IMS in a soluble form (AIFsol). AIFsol is released to the cytoplasm in response to specific death signals, and translocated to the nucleus, where it induces nuclear apoptosis. Colocalizes with EIF3G in the nucleus and perinuclear region; Tissue Specificity: Detected in muscle and skin fibroblasts (at protein level). Isoform 5 is frequently down-regulated in human cancers.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Antibody clone number
GH-1
Vial size
100ug/vial
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage
At -20°C for one year. Avoid repeated freezing and thawing.
AIFM1 protein structure - M01571 shown in red.