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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- MAB1551-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse CCR3 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse CCR3. Specifically stains mouse CCR3 transfectants but not the parental cell lines. Does not cross-react with Y3 cells transfected with human CCR3.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Antigen sequence
P51678- Isotype
- IgG
- Antibody clone number
- 83103
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Breast milk immune complexes are potent inducers of oral tolerance in neonates and prevent asthma development.
CCR3 is a target for age-related macular degeneration diagnosis and therapy.
CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation.
Ablation of type I hypersensitivity in experimental allergic conjunctivitis by eotaxin-1/CCR3 blockade.
Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils.
Toll-like receptor-2-mediated C-C chemokine receptor 3 and eotaxin-driven eosinophil influx induced by Mycobacterium bovis BCG pleurisy.
Mosconi E, Rekima A, Seitz-Polski B, Kanda A, Fleury S, Tissandie E, Monteiro R, Dombrowicz DD, Julia V, Glaichenhaus N, Verhasselt V
Mucosal immunology 2010 Sep;3(5):461-74
Mucosal immunology 2010 Sep;3(5):461-74
CCR3 is a target for age-related macular degeneration diagnosis and therapy.
Takeda A, Baffi JZ, Kleinman ME, Cho WG, Nozaki M, Yamada K, Kaneko H, Albuquerque RJ, Dridi S, Saito K, Raisler BJ, Budd SJ, Geisen P, Munitz A, Ambati BK, Green MG, Ishibashi T, Wright JD, Humbles AA, Gerard CJ, Ogura Y, Pan Y, Smith JR, Grisanti S, Hartnett ME, Rothenberg ME, Ambati J
Nature 2009 Jul 9;460(7252):225-30
Nature 2009 Jul 9;460(7252):225-30
CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation.
Medoff BD, Seung E, Hong S, Thomas SY, Sandall BP, Duffield JS, Kuperman DA, Erle DJ, Luster AD
Journal of immunology (Baltimore, Md. : 1950) 2009 Jan 1;182(1):623-35
Journal of immunology (Baltimore, Md. : 1950) 2009 Jan 1;182(1):623-35
Ablation of type I hypersensitivity in experimental allergic conjunctivitis by eotaxin-1/CCR3 blockade.
Miyazaki D, Nakamura T, Ohbayashi M, Kuo CH, Komatsu N, Yakura K, Tominaga T, Inoue Y, Higashi H, Murata M, Takeda S, Fukushima A, Liu FT, Rothenberg ME, Ono SJ
International immunology 2009 Feb;21(2):187-201
International immunology 2009 Feb;21(2):187-201
Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils.
Zimmermann N, McBride ML, Yamada Y, Hudson SA, Jones C, Cromie KD, Crocker PR, Rothenberg ME, Bochner BS
Allergy 2008 Sep;63(9):1156-63
Allergy 2008 Sep;63(9):1156-63
Toll-like receptor-2-mediated C-C chemokine receptor 3 and eotaxin-driven eosinophil influx induced by Mycobacterium bovis BCG pleurisy.
D'Avila H, Almeida PE, Roque NR, Castro-Faria-Neto HC, Bozza PT
Infection and immunity 2007 Mar;75(3):1507-11
Infection and immunity 2007 Mar;75(3):1507-11
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