CCR3

gene product
CC-CKR-3, CD193, CKR3, CMKBR3
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
776 antibodies from 41 providers.

Antibody properties

General

Applications

or Cancel
Antibody
R&D Systems
36 antibodies
antibodies-online
267 antibodies
GeneTex
9 antibodies
Novus Biologicals
39 antibodies
Abnova Corporation
7 antibodies
LifeSpan BioSciences, Inc.
105 antibodies
OriGene
15 antibodies
Boster Biological Technology
5 antibodies
Invitrogen Antibodies
21 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
Acris Antibodies GmbH
16 antibodies
Biorbyt
26 antibodies
NovoPro Bioscience Inc.
6 antibodies
NSJ Bioreagents
3 antibodies
Abgent
8 antibodies
Aviva Systems Biology
6 antibodies
ProSci
5 antibodies
Affinity Biosciences
1 antibody
Enzo Life Sciences
3 antibodies
BioLegend
25 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
St John's Laboratory
2 antibodies
FabGennix
3 antibodies
Sigma-Aldrich
3 antibodies
Proteintech Group
1 antibody
RabMAbs
2 antibodies
Abbiotec
3 antibodies
GenWay
5 antibodies
Miltenyi Biotec
28 antibodies
Creative Biolabs
29 antibodies
Abbexa
13 antibodies
Antibodies.com
3 antibodies
Leading Biology
8 antibodies
MyBioSource
13 antibodies
RayBiotech, Inc.
5 antibodies
Abiocode, Inc.
1 antibody
United States Biological
22 antibodies
Creative Diagnostics
6 antibodies
eBioscience, An Affymetrix Company
6 antibodies
Absolute Antibody
2 antibodies