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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB729P-100UG - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse CCR3 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse CCR3. Specifically stains mouse CCR3 transfectants but not the parental cell lines. Does not cross-react with Y3 cells transfected with human CCR3.
- Reactivity
- Mouse
- Host
- Rat
- Antigen sequence
P51678- Isotype
- IgG
- Antibody clone number
- 83101
- Vial size
- 100 ug
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Allergen Delivery Inhibitors: Characterisation of Potent and Selective Inhibitors of Der p 1 and Their Attenuation of Airway Responses to House Dust Mite Allergens.
A prominent air pollutant, Indeno[1,2,3-cd]pyrene, enhances allergic lung inflammation via aryl hydrocarbon receptor.
Self-renewal and phenotypic conversion are the main physiological responses of macrophages to the endogenous estrogen surge.
CCL2/CCR2 Regulates the Tumor Microenvironment in HER-2/neu-Driven Mammary Carcinomas in Mice.
The TLR7 ligand 9-benzyl-2-butoxy-8-hydroxy adenine inhibits IL-17 response by eliciting IL-10 and IL-10-inducing cytokines.
Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice.
Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling.
Sensitization by intratracheally injected dendritic cells is independent of antigen presentation by host antigen-presenting cells.
Ablation of type I hypersensitivity in experimental allergic conjunctivitis by eotaxin-1/CCR3 blockade.
Treatment with anti-CC chemokine receptor 3 monoclonal antibody or dexamethasone inhibits the migration and differentiation of bone marrow CD34 progenitor cells in an allergic mouse model.
Zhang J, Chen J, Zuo J, Newton GK, Stewart MR, Perrior TR, Garrod DR, Robinson C
International journal of molecular sciences 2018 Oct 15;19(10)
International journal of molecular sciences 2018 Oct 15;19(10)
A prominent air pollutant, Indeno[1,2,3-cd]pyrene, enhances allergic lung inflammation via aryl hydrocarbon receptor.
Wong TH, Lee CL, Su HH, Lee CL, Wu CC, Wang CC, Sheu CC, Lai RS, Leung SY, Lin CC, Wei YF, Wang CJ, Lin YC, Chen HL, Huang MS, Yen JH, Huang SK, Suen JL
Scientific reports 2018 Mar 26;8(1):5198
Scientific reports 2018 Mar 26;8(1):5198
Self-renewal and phenotypic conversion are the main physiological responses of macrophages to the endogenous estrogen surge.
Pepe G, Braga D, Renzi TA, Villa A, Bolego C, D'Avila F, Barlassina C, Maggi A, Locati M, Vegeto E
Scientific reports 2017 Mar 20;7:44270
Scientific reports 2017 Mar 20;7:44270
CCL2/CCR2 Regulates the Tumor Microenvironment in HER-2/neu-Driven Mammary Carcinomas in Mice.
Chen X, Wang Y, Nelson D, Tian S, Mulvey E, Patel B, Conti I, Jaen J, Rollins BJ
PloS one 2016;11(11):e0165595
PloS one 2016;11(11):e0165595
The TLR7 ligand 9-benzyl-2-butoxy-8-hydroxy adenine inhibits IL-17 response by eliciting IL-10 and IL-10-inducing cytokines.
Vultaggio A, Nencini F, Pratesi S, Maggi L, Guarna A, Annunziato F, Romagnani S, Parronchi P, Maggi E
Journal of immunology (Baltimore, Md. : 1950) 2011 Apr 15;186(8):4707-15
Journal of immunology (Baltimore, Md. : 1950) 2011 Apr 15;186(8):4707-15
Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice.
Nel HJ, Hams E, Saunders SP, Mangan NE, Smith P, Atzberger A, Flavell RA, Akira S, McKenzie AN, Fallon PG
Journal of immunology (Baltimore, Md. : 1950) 2011 Apr 15;186(8):4631-9
Journal of immunology (Baltimore, Md. : 1950) 2011 Apr 15;186(8):4631-9
Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling.
Song DJ, Cho JY, Lee SY, Miller M, Rosenthal P, Soroosh P, Croft M, Zhang M, Varki A, Broide DH
Journal of immunology (Baltimore, Md. : 1950) 2009 Oct 15;183(8):5333-41
Journal of immunology (Baltimore, Md. : 1950) 2009 Oct 15;183(8):5333-41
Sensitization by intratracheally injected dendritic cells is independent of antigen presentation by host antigen-presenting cells.
Kuipers H, Soullié T, Hammad H, Willart M, Kool M, Hijdra D, Hoogsteden HC, Lambrecht BN
Journal of leukocyte biology 2009 Jan;85(1):64-70
Journal of leukocyte biology 2009 Jan;85(1):64-70
Ablation of type I hypersensitivity in experimental allergic conjunctivitis by eotaxin-1/CCR3 blockade.
Miyazaki D, Nakamura T, Ohbayashi M, Kuo CH, Komatsu N, Yakura K, Tominaga T, Inoue Y, Higashi H, Murata M, Takeda S, Fukushima A, Liu FT, Rothenberg ME, Ono SJ
International immunology 2009 Feb;21(2):187-201
International immunology 2009 Feb;21(2):187-201
Treatment with anti-CC chemokine receptor 3 monoclonal antibody or dexamethasone inhibits the migration and differentiation of bone marrow CD34 progenitor cells in an allergic mouse model.
Ben S, Li X, Xu F, Xu W, Li W, Wu Z, Huang H, Shi H, Shen H
Allergy 2008 Sep;63(9):1164-76
Allergy 2008 Sep;63(9):1164-76
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CCR3 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CCR3 PE-conjugated Monoclonal Antibody (Catalog # FAB729P) and Rat Anti-Mouse Gr-1/Ly-6G Fluoresein-conjugated Monoclonal Antibody (Catalog # FAB1037F). Quadrant markers were set based on control antibody staining (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.
