310709

antibody from BioLegend
Targeting: CCR3 CC-CKR-3, CD193, CKR3, CMKBR3
Provider product page for 310709
Flow cytometry

Antibody data

Product number
310709 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#310709, RRID:AB_2275699
Product name
Alexa Fluor® 647 anti-human CD193 (CCR3) [5E8]
Antibody type
Monoclonal
Antigen
CD193 (CCR3)
Description
CC-chemokine receptor 3 (CCR3), also known as CC CKR3, MIP1-alpha receptor like-2, eotaxin receptor, and CD193, is a member of G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.
Reactivity
Human
Host
Mouse
Conjugate
Red dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
CCR3 protein structure - 310709 shown in red.