Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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Comment
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- Product number
- 18220-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18220-1-AP, RRID:AB_2298441
- Product name
- IkB Alpha antibody
- Antibody type
- Polyclonal
- Description
- IkB Alpha antibody (Cat. #18220-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mechanistic studies on the alleviation of ANIT-induced cholestatic liver injury by Polygala fallax Hemsl. polysaccharides.
The Effect of Bergenin on Isonicotinic Acid Hydrazide and Rifampicin-Induced Liver Injury Revealed by RNA Sequencing.
MiR-376a-3p increases cell apoptosis in acute myeloid leukemia by targeting MT1X.
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
A20-Binding Inhibitor of NF-κB 1 Ameliorates Neuroinflammation and Mediates Antineuroinflammatory Effect of Electroacupuncture in Cerebral Ischemia/Reperfusion Rats.
Tubeimoside I improves survival of mice in sepsis by inhibiting inducible nitric oxide synthase expression.
Electroacupuncture Suppresses the NF-κB Signaling Pathway by Upregulating Cylindromatosis to Alleviate Inflammatory Injury in Cerebral Ischemia/Reperfusion Rats.
Upregulation of neuronal zinc finger protein A20 expression is required for electroacupuncture to attenuate the cerebral inflammatory injury mediated by the nuclear factor-kB signaling pathway in cerebral ischemia/reperfusion rats.
Peroxiredoxin 6 attenuates ischemia‑ and hypoxia‑induced liver damage of brain‑dead donors.
Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma.
Guan G, Cao H, Tang Z, Zhang K, Zhong M, Lv R, Wan W, Guo F, Wang Y, Gao Y
Journal of ethnopharmacology 2024 Jun 28;328:118108
Journal of ethnopharmacology 2024 Jun 28;328:118108
The Effect of Bergenin on Isonicotinic Acid Hydrazide and Rifampicin-Induced Liver Injury Revealed by RNA Sequencing.
Li T, Yang C, Cao H, Mo S, Li B, Huang Z, Zhang R, Wu J, Zhang K, Gao Y
Molecules (Basel, Switzerland) 2023 Jul 19;28(14)
Molecules (Basel, Switzerland) 2023 Jul 19;28(14)
MiR-376a-3p increases cell apoptosis in acute myeloid leukemia by targeting MT1X.
Xin X, Xu Z, Wei J, Zhang Y
Cancer biology & therapy 2022 Dec 31;23(1):234-242
Cancer biology & therapy 2022 Dec 31;23(1):234-242
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
Cheng Z, Lv D, Luo M, Wang R, Guo Y, Yang X, Huang L, Li X, Li C, Shang FF, Huang B, Shen J, Luo S, Yan J
European journal of pharmacology 2021 Aug 15;905:174186
European journal of pharmacology 2021 Aug 15;905:174186
A20-Binding Inhibitor of NF-κB 1 Ameliorates Neuroinflammation and Mediates Antineuroinflammatory Effect of Electroacupuncture in Cerebral Ischemia/Reperfusion Rats.
Zhou X, Lu W, Wang Y, Li J, Luo Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6980398
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6980398
Tubeimoside I improves survival of mice in sepsis by inhibiting inducible nitric oxide synthase expression.
Luo M, Luo S, Cheng Z, Yang X, Lv D, Li X, Guo Y, Li C, Yan J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110083
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110083
Electroacupuncture Suppresses the NF-κB Signaling Pathway by Upregulating Cylindromatosis to Alleviate Inflammatory Injury in Cerebral Ischemia/Reperfusion Rats.
Jiang J, Luo Y, Qin W, Ma H, Li Q, Zhan J, Zhang Y
Frontiers in molecular neuroscience 2017;10:363
Frontiers in molecular neuroscience 2017;10:363
Upregulation of neuronal zinc finger protein A20 expression is required for electroacupuncture to attenuate the cerebral inflammatory injury mediated by the nuclear factor-kB signaling pathway in cerebral ischemia/reperfusion rats.
Zhan J, Qin W, Zhang Y, Jiang J, Ma H, Li Q, Luo Y
Journal of neuroinflammation 2016 Oct 3;13(1):258
Journal of neuroinflammation 2016 Oct 3;13(1):258
Peroxiredoxin 6 attenuates ischemia‑ and hypoxia‑induced liver damage of brain‑dead donors.
Tu Q, Xiong Y, Fan L, Qiao B, Xia Z, Hu L, Wang Y, Peng G, Ye Q
Molecular medicine reports 2016 Jan;13(1):753-61
Molecular medicine reports 2016 Jan;13(1):753-61
Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma.
Wang F, Yang JL, Yu KK, Xu M, Xu YZ, Chen L, Lu YM, Fang HS, Wang XY, Hu ZQ, Li FF, Kan L, Luo J, Wang SY
Molecular cancer 2015 Jan 27;14(1):10
Molecular cancer 2015 Jan 27;14(1):10
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HL-60 cells were subjected to SDS PAGE followed by western blot with 18220-1-AP(NFKBIA antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IkB alpha antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human IkB alpha. This antibody recognizes human,mouse,rat antigen. The IkB alpha antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 18220-1-AP(NFKBIA antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue