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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN357736 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (N-Term), (Sumoylation Site) antibody
- Antibody type
- Polyclonal
- Description
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term, Sumoylation Site
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Okadaic acid induces sustained activation of NFkappaB and degradation of the nuclear IkappaBalpha in human neutrophils.
Induced stabilization of IkappaBalpha can facilitate its re-synthesis and prevent sequential degradation.
Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase.
HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation.
Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1.
Miskolci V, Castro-Alcaraz S, Nguyen P, Vancura A, Davidson D, Vancurova I
Archives of biochemistry and biophysics 2003 Sep 1;417(1):44-52
Archives of biochemistry and biophysics 2003 Sep 1;417(1):44-52
Induced stabilization of IkappaBalpha can facilitate its re-synthesis and prevent sequential degradation.
Place RF, Haspeslagh D, Giardina C
Journal of cellular physiology 2003 Jun;195(3):470-8
Journal of cellular physiology 2003 Jun;195(3):470-8
Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase.
Takada Y, Mukhopadhyay A, Kundu GC, Mahabeleshwar GH, Singh S, Aggarwal BB
The Journal of biological chemistry 2003 Jun 27;278(26):24233-41
The Journal of biological chemistry 2003 Jun 27;278(26):24233-41
HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation.
Parcellier A, Schmitt E, Gurbuxani S, Seigneurin-Berny D, Pance A, Chantôme A, Plenchette S, Khochbin S, Solary E, Garrido C
Molecular and cellular biology 2003 Aug;23(16):5790-802
Molecular and cellular biology 2003 Aug;23(16):5790-802
Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1.
Kim YS, Lee JY, Son MY, Park W, Bae YS
The Journal of biological chemistry 2003 Aug 1;278(31):28462-9
The Journal of biological chemistry 2003 Aug 1;278(31):28462-9
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