624902

antibody from BioLegend
Targeting: NFKBIA IkappaBalpha, IKBA, MAD-3, NFKBI
Provider product page for 624902
Western blot
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
624902 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#624902, RRID:AB_315994
Product name
Purified anti-IkB-‡
Antibody type
Polyclonal
Antigen
Peptide mapping to the carboxy terminus of human IκB-α
Description
IκB-α is an inhibitory protein that binds the NFκB complex and retains this complex in the cytoplasm where it cannot activate transcription. Upon cellular stimulation, the IκB proteins are phosphorylated and degraded via the ubiquitin pathway allowing nuclear translocation of NFκB. The NFκB complex binds DNA to activate gene expression of a number of a variety of proteins involved in inflammation, cellular proliferation, differentiation, and apoptosis. Poly6249 recognizes the C-terminal region of human, mouse, rat IKB-α and has been shown to be useful for Western blotting, immunoprecipitation, and immunohistochemistry.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Vial size
200 µl
Storage
The antibody solution should be stored undiluted at 4°C. DO NOT FREEZE.
NFKBIA protein structure - 624902 shown in red.